Neighbouring Technologies | DGMed ECT Portal

How Do These Differ from Electroporation?

In electroporation the cell membrane is made transiently or permanently permeable by an electric pulse above a threshold. None of the technologies below does this; one of them (food and environmental PEF) is electroporation but not a medical use.

Technology	What it does	Publications
Electrochemical Ablation (EChT)	Produces cell death by driving a direct current that changes tissue pH and generates electrolysis products; applied on its own it involves no pulse that raises membrane permeability. The set also holds studies that combine electrolysis with electroporation pulses (E²); these sit on both sides of the boundary and do not enter the corpus.	37
Thermal and Other Ablation Methods	Radiofrequency, microwave, cryoablation and focused ultrasound. Tissue death is by heat or freezing, not electroporation.	21
Bioelectromagnetic Fields	Effects of low-voltage electric and magnetic fields on cells. No pulse exceeding the membrane permeability threshold is applied.	11
Intralesional Chemotherapy without Electroporation	Studies in which the drug is injected directly into the lesion with no electric pulse applied. The comparison ground for electrochemotherapy.	10
Food, Microbial and Environmental PEF	Pulsed electric field in food processing, microbial control and environmental applications. Electroporation, but not a medical use.	6

The records on this page are not included in the portal's publication counts. The oncology corpus and the extended electroporation corpus count electroporation publications only; the documents here are kept in the source archive as context and are reported with their own figures.

Electrochemical Ablation (EChT)

The archive holds 37 documents.

Year	Authors	Title
2026	Liu et al	Development of an Electro-Responsive Sorafenib-Loaded Polypyrrole Film-Modified Nickel-Titanium Alloy
2026	Guo et al	Electrochemical tumor ablation Applications and future prospects
2026	Qin et al	Electrode material and electrical delivery mode shape the mechanisms and efficacy of electrochemical
2026	Ondráčková	The Faraday Scalpel Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models
2025	Šmerc et al	An experimentally validated numerical model of pH changes in surrogate tissue induced by electroporation
2024	Joe et al	Electric Field-Responsive Gold Nanoantennas for the Induction of a Locoregional Tumor pH Change Using
2023	Ma	A Novel Strategy of Combined Pulsed Electro-Oxidation and Electrolysis for Degradation of Sulfa
2023	Miripour et al	Electrochemical therapy (EChT) of cancer tumor with an external anode, a way to achieve pathological
2020	Qi et al	A green, efficient and precise hydrogen therapy of cancer based on in vivo electrochemistry
2020	Stein et al	MR Imaging Enables Real-Time Monitoring of In Vitro Electrolytic Ablation of Hepatocellular Carcinoma
2020	Miripour et al	Nanoporous platinum needle for cancer tumor destruction by EChT and impedance-based intra-therapeutic
2019	Lv et al	Molecular and histological study on the effects of electrolytic electroporation on the liver
2019	Klein	The combination of electroporation and electrolysis (E2) employing different electrode arrays f
2018	Perkons et al	Electrolytic ablation enables cancer cell targeting through pH modulation
2018	Soba et al	Integrated analysis of the potential, electric field, temperature, pH and tissue damage generated by
2018	Duong et al	Smart vaccine delivery based on microneedle arrays decorated with ultra-pH-responsive copolymers for
2017	Sun et al	Amorphous liquid metal electrodes enabled conformable electrochemical therapy of tumors
2017	Ho	Combining Electrolysis and Electroporation for Tissue Ablation
2016	Zhong et al	Electrochemical treatment an effective way of dealing with extensive venous malformations of the oral
2016	Rubinsky et al	Minimally Invasive, Non-Thermal Tissue Ablation with a Single Exponential Decay Electrolytic
2016	Stehling et al	Synergistic Combination of Electrolysis and Electroporation for Tissue Ablation
2016	Phillips et al	Tissue Ablation by a Synergistic Combination of Electroporation and Electrolysis Delivered by a Single
2015	Phillips et al	Modulating electrolytic tissue ablation with reversible electroporation pulses
2013	Maglietti et al	The role of pH fronts in tissue electroporation based treatments
2012	Czymek et al	Intrahepatic radiofrequency ablation versus electrochemical treatment in vivo
2008	Hinz et al	Electrolytic ablation is as effective as radiofrequency ablation in the treatment of artificial liver
2006	Xie et al	A new local ablation for solid malignant tumours Anti-tumour effect of hyperthermal and electrochemical
2006	Xie et al	A new local ablation for unresectable primary liver tumor effect of electrothermal and electrochemical
2004	von Euler et al	Cell proliferation and apoptosis in rat mammary cancer after electrochemical treatment
2004	Morrison et al	Perductal electrolytic ablation of the porcine pancreas A minimally invasive option-studies of morbidity
2003	Finch et al	Experimental studies of serum cytokine concentration following pancreatic electrolytic ablation
2003	Wemyss-Holden et al	Palliation of pancreatic cancer using electrolytic ablation
2001	von Euler et al	Electrochemical treatment (EChT) effects in rat mammary and liver tissue. In vivo optimizing of a
2001	Fosh et al	Electrolytic ablation of the rat pancreas a feasibility trial
2000	Wójcicki et al	Antitumor effect of electrochemical therapy on transplantable mouse cancers
2000	Berry et al	Electrolytic Ablation of Colorectal Liver Metastases 1-Year Histological Patient Follow-Up
2000	Wu Guoju et al	Orta-ileri evre pankreas kuyruk-govde kanserinde elektrokimyasal terapi ve intraperitoneal kemoterapi pompasi

Thermal and Other Ablation Methods

The archive holds 21 documents.

Year	Authors	Title
2026	Dong	Global research trends and foci of ablation therapies for liver tumours a scientometric study
2026	Mills et al	Patient‐Reported Outcome Measures Following Pulsed‐Field Ablation Versus Thermal Ablation of Atrial
2025	Dan et al	A systematic review and meta-analysis of laparoscopic partial nephrectomy versus laparoscopic focal
2025	Wang et al	Advancements in the application of ablative therapy and its combination with immunotherapy in
2025	Yu et al	Advances in the combination of immunoadjuvants and tumor ablation Mediating immune effects to enhance
2025	Maciulevičius et al	Ca2+ sonotransfer into breast cancer cells in a suspension, 3-D spheroid and subcutaneous tumor models
2025	Fernandez	Duodenal mucosal ablation An emerging therapeutic concept for metabolic dysfunction-associated
2025	Lai	Multiparametric MRI before and after Focal Therapy for Prostate Cancer Pearls and Pitfalls for
2025	Yun	The growing armamentarium of image-guided tumor ablation in interventional oncology
2025	Eskandar	Ultrasonido focalizado de alta intensidad con el dispositivo Focal One para el cáncer de próstata
2025	Ong et al	Use of Histotripsy to Rapidly Relieve Biliary Obstruction in a Patient With Recurrent Hilar
2024	Kumar et al	The use of focal therapy for the treatment of prostate cancer in Canada
2023	Wong	New Surgical Approach to Treat Fibroids and Solid Tumors - Thermal and Nonthermal Ablation
2022	Gu et al	Efficacy of immunotherapy with combination of cryotherapy and topical imiquimod for treatment of Kaposi
2021	Hendel et al	Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in
2019	Boetto et al	Laparoscopic Microwave Ablation and Portal Vein Occlusion for Staged Hepatectomy
2018	Yoon et al	Focal therapy versus robot-assisted partial nephrectomy in the management of clinical T1 renal masses
2014	Wagstaff et al	Thermal ablation in renal cell carcinoma management
2013	Bozzini et al	Focal therapy of prostate cancer energies and procedures
2008	Larkin et al	Effective Tumor Treatment Using Optimized Ultrasound-Mediated Delivery of Bleomycin
2006	Cho et al	Percutaneous Radiofrequency Ablation Therapy of Hepatocellular Carcinoma Using Multitined Expandable

Bioelectromagnetic Fields

The archive holds 11 documents.

Year	Authors	Title
2026	Jiang et al	Anti-PD-1 blockade reverses low-intensity electric stimulation-driven pancreatic cancer progression
2026	Mandija et al	Clinical Applications of Electrical Conductivity Imaging Using MRI
2026	Sherif et al	Integrated electrical modeling of circulating tumor cells for enhanced dielectrophoretic trapping and
2026	Li	Nano-in-Micro GelMA depots assist electro-thermal-immuno orchestral treatment for solid triple
2024	Bryant et al	Nanoparticles use magnetoelectricity to target and eradicate cancer cells
2021	Mansourian et al	The investigation of Pulse-Modulated GSM-900 MHz electromagnetic field effects on the
2014	Prosen	Mcam Silencing With RNA Interference Using Magnetofection has Antitumor Effect in Murine Melano
2010	Beebe et al	Bioelectric Applications for Treatment of Melanoma
2010	Berg et al	Bioelectromagnetic Field Effects on Cancer Cells and Mice Tumors
2003	Miyazaki et al	Possible Involvement of Antitumor Immunity in the Eradication of Colon 26 Induced by Low-Voltage
2002	Weaver	Understanding conditions for which biological effects of nonionizing electromagnetic fields can be

Intralesional Chemotherapy without Electroporation

The archive holds 10 documents.

Year	Authors	Title
2021	Zawit	Current status of intralesional agents in treatment of malignant melanoma
2019	Mohr et al	Real-World Use of Talimogene Laherparepvec in German Patients with Stage IIIB to IVM1a Melanoma
2010	Keuker	The Use of Bleomycin for Sclerotherapy in Lymphatic and Venous Malformations
2007	Théon et al	Long-term outcome associated with intratumoral chemotherapy with cisplatin for cutaneous tumors in
2006	Hewes et al	Use of cisplatin-containing biodegradable beads for treatment of cutaneous neoplasia in equidae 59 cases
2004	Boria et al	Evaluation of cisplatin combined with piroxicam for the treatment of oral malignant melanoma and oral
1999	Théon et al	Comparison of perioperative versus postoperative intratumoral administration of cisplatin for treatment
1998	Yoshida et al	The effect of intralesional bleomycin on canine acanthomatous epulis
1994	Théon et al	Perioperative intratumoral administration of cisplatin for treatment of cutaneous tumors in Equidae
1991	Théon et al	Localized thermo-cisplatin therapy A pilot study in spontaneous canine and feline tumours

Food, Microbial and Environmental PEF

The archive holds 6 documents.

Year	Authors	Title
2026	Muttaqin et al	Colloid-Osmotic Swelling Acts as an Upstream Trigger for Electro-Apoptosis in HeLa Cells Exposed to
2025	Dermesonlouoglou	Effect of Pulsed Electric Fields and Osmotic Dehydration on the Quality of Modified-Atmosphere-
2025	Rybak	Energy-Dependent Effects of Pulsed Electric Field (PEF) Treatment on the Quality Attributes, Bi
2019	Feng	Analysis of Factors Influencing the Transmembrane Voltage Induced in Filamentous Fungi by Pulse
2015	Kang et al	A novel electroporation system for efficient molecular delivery into Chlamydomonas reinhardtii with a
2009	Golberg et al	Irreversible Electroporation for Microbial Control of Drugs in Solution