Group: Urogynaecological Tumours
Ovarian Tumours
Electroporation in ovarian tumours has been studied through peritoneal spread and preclinical models; the corpus holds no clinical series for this area.
Clinical publications: randomized, prospective and retrospective studies, case series and case reports. Preclinical publications: animal, in vitro, modelling and experimental biophysics studies.
Clinical and Technical Data Reported in the Publications
The sum of the fields reported in the full text of the 10 publications in this area. The numbers are summed, not interpreted.
The totals are not a count of unique patients: the same cohort may have been reported in more than one publication.
Literature Status by Method
Publication count, clinical and preclinical split, literature volume and publication span for each clinical method. The badge at the top of the page summarises the ECT record only; the full split by method is here.
Electrochemotherapy (ECT)
Exploratory / low-volume literaturethreshold 0/7 records
No record for this method feeds the volume label.
2009–2026
Irreversible electroporation (IRE)
Exploratory / low-volume literaturethreshold 1/2 records
Clinical and preclinical split of that figure: 0 clinical, 1 preclinical.
2017–2026
Other electroporation applications
This set does not name a single clinical method; no literature volume is assigned.
2017–2017
Mechanisms Mentioned in Abstracts
The figure is the number of abstracts mentioning the mechanism. A mention does not mean it was demonstrated in that study.
Study Type Distribution
The percentage gives the share of the whole area.
| Study type | Publications | Share within this area |
|---|---|---|
| Review | 1 | 10% |
| Animal Study | 3 | 30% |
| In Vitro Study | 6 | 60% |
Publication Table
10 publication records sorted by study design. Click a title to open the citation, mechanism and full abstract drawer.
Classifications are generated automatically and can be wrong for individual records. Methodology
| Regime | Publication | Year | Study type | Model | Mechanism | Patients / lesions | Device | Agent and route | Reported outcome | Abstract |
|---|---|---|---|---|---|---|---|---|---|---|
| IRE | Bose · Indian J Gynecol Oncolog | 2026 | Review | Literature Analysis | Reversible Membrane Permeabilisation, Irreversible Pore Formation and Cell Death | – | – | cisplatin | – | Purpose This review synthesizes current research from Irreversible electroporation in Ovarian Cancer regarding the expanding roles of electroporation in ovarian cancer. It addresses how cont… |
| ECT | Łapińska et al · Biomed Pharmacother | 2024 | Animal Study | Animal (In Vivo) | Increased Intracellular Cisplatin Accumulation, Calcium Electroporation and ATP Depletion | – | – | calcium chloride | – | Calcium electroporation (CaEP) is an efficient approach for ovarian cancer treatment. It causes cell death by introducing elevated levels of calcium into cells. In this work, the research fo… |
| IRE | Rolong et al · Integr Biol (Camb) | 2017 | Animal Study | Animal (In Vivo) | Irreversible Pore Formation and Cell Death, Reversible Membrane Permeabilisation | – | custom-built electrical stimulator, BTX ECM830 | – | cell viability 436% (9 samples) | We explored the use of irreversible electroporation (IRE) and high-frequency irreversible electroporation (H-FIRE) to induce cell death of tumor-initiating cells using a mouse ovarian surfac… |
| ECT | Yang et al · J Exp Clin Cancer Res | 2009 | Animal Study | Animal (In Vivo) | Optimisation of Pulse Parameters, Apoptosis Induction | – | SPEF generator | – | tumour volume change 513.9 cm³ (6 animals) | Background: Patients received electrochemotherapy often associated with unpleasant sensations mainly result from low-frequency electric pulse induced muscle contractions. Increasing the repe… |
| ECT | Marverti et al · – | 2026 | In Vitro Study | Cell Culture | Increased Intracellular Cisplatin Accumulation, Potentiation of Cytotoxic Drug Permeability | – | Genedrive electroporator | other | – | Ovarian and colorectal cancers have the highest incidence and mortality in the world, after breast cancer. Despite the initial response to Pt-drugs or 5-fluorouracil (5-FU), many cancer cell… |
| ECT | Scuderi et al · Radiol Oncol | 2024 | In Vitro Study | Cell Culture | Increased Intracellular Cisplatin Accumulation, Gene Electrotransfer (Plasmid DNA) | – | L-POR V0.1, BTX Gemini X2 | cisplatin | – | Background: Electrochemotherapy (ECT) is a treatment involving the administration of chemotherapeutics drugs followed by the application of 8 square monopolar pulses of 100 μs duration at a … |
| ECT | Łapińska et al · Pharmaceutics | 2020 | In Vitro Study | Cell Culture | Increased Intracellular Cisplatin Accumulation, Apoptosis Induction | – | BTX ECM 820, PPG-20, PPG-20 generator | cisplatin | – | Estrogens (Es) play a significant role in the carcinogenesis and progression of ovarian malignancies. Depending on the concentration, Es may have a protective or toxic effect on cells. Moreo… |
| Other EP | Salimi et al · Biomicrofluidics | 2017 | In Vitro Study | Cell Culture | Tissue Conductivity and Impedance Change, Electric Field Distribution and Modelling | – | – | – | – | Applying sufficiently strong pulsed electric fields to a cell can permeabilize the membrane and subsequently affect its dielectric properties. In this study, we employ a microfluidic dielect… |
| ECT | Saczko et al · Neoplasma | 2016 | In Vitro Study | Cell Culture | Increased Intracellular Bleomycin Accumulation | – | BTX ECM830 | bleomycin | – | The presented study aimed to evaluate in vitro the effectiveness of improvement standard chemotherapy with bleomycin by electroporation in two various ovarian cancer cell lines. Two human ov… |
| ECT | Saczko et al · Biomed Pharmacother | 2014 | In Vitro Study | Cell Culture | Increased Intracellular Cisplatin Accumulation, Reversible Membrane Permeabilisation | – | BTX ECM830 | other | – | High electric field, applied to plasma membrane, affects organization of the lipid molecules, generating transient hydrophilic electropores. The application of the cell membrane electroporat… |
Limitations
Publication volume is not clinical efficacy or evidence quality. It describes how much literature exists in the area and of what kind; it does not indicate how strongly the treatment is supported, guideline endorsement or regulatory status.
Patient totals are not a count of unique patients. The same cohort may have been reported in more than one publication; the totals are not a meta-analysis.
How the corpus was assembled, the tier thresholds, the definition of a clinical publication and why methods are counted separately: Literature Map.