Group: Urogynaecological Tumours
Ovarian Tumours
Electroporation in ovarian tumours has been studied through peritoneal spread and preclinical models; the corpus holds no clinical series for this area.
Clinical publications: randomized, prospective and retrospective studies, case series and case reports. Preclinical publications: animal, in vitro, modelling and experimental biophysics studies.
Literature Status by Method
Publication count, clinical and preclinical split, literature maturity and publication span for each clinical method. The badge at the top of the page summarises the ECT record only; the full split by method is here.
Electrochemotherapy (ECT)
Exploratory literaturethreshold 0/7
No record for this method entered the maturity calculation; the records are marked in the validation ledger as conflicting, insufficient or out of scope.
2009–2026
Irreversible electroporation (IRE)
Exploratory literaturethreshold 1/2
Validated records entering the maturity calculation: 1 (clinical 0, preclinical 1), 50% of the records for this method.
2017–2026
Other electroporation applications
This set does not name a single clinical method; no literature maturity is assigned.
2017–2017
Mechanisms Mentioned in Abstracts
Mechanism names are detected by automatic matching over publication abstracts; the figure is the number of publications containing the name. A mention does not mean the mechanism was demonstrated in that study.
Study Type Distribution
Bar length is scaled to the most common study type; the percentage gives the share of the whole area. Colour marks the study-type band, on the same scale as the literature map.
| Study type | Publications | Share within this area |
|---|---|---|
| Review | 1 | 10% |
| Animal Study | 3 | 30% |
| In Vitro Study | 6 | 60% |
Literature Evidence Table
10 publications listed in order of evidence strength. Click a title to open the citation, mechanism and full abstract drawer.
The study type, model and mechanism columns are assigned automatically and can be wrong for individual records; the abstract column is taken either from the publication's own abstract or from the opening text of the source PDF. The labels are there for scanning and filtering, not as record-level verified data; consult the full text before acting on any single publication. The classification rules and known errors are on the Literature Map.
| Regime | Publication | Year | Study type | Model | Mechanism | Abstract |
|---|---|---|---|---|---|---|
| IRE | Bose · Indian J Gynecol Oncolog | 2026 | Review | Literature Analysis | Reversible Membrane Permeabilisation, Irreversible Pore Formation and Cell Death | Purpose This review synthesizes current research from Irreversible electroporation in Ovarian Cancer regarding the expanding roles of electroporation in ovarian cancer. It addresses how cont… |
| ECT | Łapińska et al · Biomed Pharmacother | 2024 | Animal Study | Animal (In Vivo) | Increased Intracellular Cisplatin Accumulation, Calcium Electroporation and ATP Depletion | Calcium electroporation (CaEP) is an efficient approach for ovarian cancer treatment. It causes cell death by introducing elevated levels of calcium into cells. In this work, the research fo… |
| IRE | Rolong et al · Integr Biol (Camb) | 2017 | Animal Study | Animal (In Vivo) | Irreversible Pore Formation and Cell Death, Reversible Membrane Permeabilisation | We explored the use of irreversible electroporation (IRE) and high-frequency irreversible electroporation (H-FIRE) to induce cell death of tumor-initiating cells using a mouse ovarian surfac… |
| ECT | Yang et al · J Exp Clin Cancer Res | 2009 | Animal Study | Animal (In Vivo) | Optimisation of Pulse Parameters, Apoptosis Induction | Background: Patients received electrochemotherapy often associated with unpleasant sensations mainly result from low-frequency electric pulse induced muscle contractions. Increasing the repe… |
| ECT | Marverti et al · – | 2026 | In Vitro Study | Cell Culture | Increased Intracellular Cisplatin Accumulation, Potentiation of Cytotoxic Drug Permeability | Ovarian and colorectal cancers have the highest incidence and mortality in the world, after breast cancer. Despite the initial response to Pt-drugs or 5-fluorouracil (5-FU), many cancer cell… |
| ECT | Scuderi et al · Radiol Oncol | 2024 | In Vitro Study | Cell Culture | Increased Intracellular Cisplatin Accumulation, Gene Electrotransfer (Plasmid DNA) | Background: Electrochemotherapy (ECT) is a treatment involving the administration of chemotherapeutics drugs followed by the application of 8 square monopolar pulses of 100 μs duration at a … |
| ECT | Łapińska et al · Pharmaceutics | 2020 | In Vitro Study | Cell Culture | Increased Intracellular Cisplatin Accumulation, Apoptosis Induction | Estrogens (Es) play a significant role in the carcinogenesis and progression of ovarian malignancies. Depending on the concentration, Es may have a protective or toxic effect on cells. Moreo… |
| Other EP | Salimi et al · Biomicrofluidics | 2017 | In Vitro Study | Cell Culture | Tissue Conductivity and Impedance Change, Electric Field Distribution and Modelling | Applying sufficiently strong pulsed electric fields to a cell can permeabilize the membrane and subsequently affect its dielectric properties. In this study, we employ a microfluidic dielect… |
| ECT | Saczko et al · Neoplasma | 2016 | In Vitro Study | Cell Culture | Increased Intracellular Bleomycin Accumulation | The presented study aimed to evaluate in vitro the effectiveness of improvement standard chemotherapy with bleomycin by electroporation in two various ovarian cancer cell lines. Two human ov… |
| ECT | Saczko et al · Biomed Pharmacother | 2014 | In Vitro Study | Cell Culture | Increased Intracellular Cisplatin Accumulation, Reversible Membrane Permeabilisation | High electric field, applied to plasma membrane, affects organization of the lipid molecules, generating transient hydrophilic electropores. The application of the cell membrane electroporat… |
Limitations
The counts on this page are bounded by the scope of the source PDF archive and are not a systematic review of the area's literature.
A literature maturity label reflects the number of publications, not their methodological quality: it describes how much literature exists in the area and of what kind, not how strongly the treatment is supported. It does not indicate clinical use, guideline endorsement, reimbursement coverage or regulatory status, and it is not a formal GRADE assessment. The definitions and thresholds of the four tiers are on the Literature Map.
The “clinical publications” figure on this page (0) uses the portal's single definition: primary clinical studies, case series and case reports. Systematic reviews and guidelines are not included. The count feeding the badge threshold is narrower and does not count case reports; no publication in this area enters that threshold count under any method, and the badge at the top of the page rests on the ECT count alone. The two counts are not the same and cannot stand in for one another; the full threshold table is on the Literature Map.
1 of the 10 records in this area enter the threshold count. The remaining 9 are marked in the validation ledger as conflicting, insufficient or out of scoring; they appear in the table below but affect no threshold and no badge. That share (10%) is not equal across areas: it is 13% portal-wide and ranges from 0% to 42% by area. Two areas' badges therefore cannot be compared directly; a lower badge can reflect narrower verification coverage as much as a narrower literature.
Literature maturity on this page is given separately for each clinical method. The methods present in this area are: Electrochemotherapy (ECT), Irreversible electroporation (IRE), Other electroporation applications. Methods may share the same biophysical basis but they are distinct treatments; evidence gathered for one method cannot be generalised to another.