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Grup: Özel Endikasyonlar

ECT: Keşifsel / düşük hacimli literatür122 yayın

Veteriner Onkoloji

Elektrokemoterapi veteriner onkolojide, sahipli hayvanlarda kendiliğinden gelişen tümörler üzerinde uzun süredir klinik olarak çalışılmaktadır. Bu kayıtlar insan endikasyonlarının kanıtı değildir; ancak kendiliğinden tümör taşıyan büyük hayvanlarda doz, elektrot ve yanıt verisi ürettikleri için translasyonel bir köprü oluşturur.

158yayın kaydıtekilleştirildiğinde 157 bağımsız çalışma
27klinik yayın kaydı
107preklinik yayın kaydı
19derleme
1997–2026yayın aralığı

Klinik yayın: randomize, prospektif ve retrospektif çalışma, vaka serisi ve vaka raporu. Preklinik yayın: hayvan, in vitro, modelleme ve deneysel biyofizik çalışmaları.

Yayınların Bildirdiği Klinik ve Teknik Veriler

Bu alandaki 158 yayının 157 tanesinde tam metinde bildirilen alanların toplamı. Sayılar toplanır, yorumlanmaz.

Yayınlarda bildirilen hasta sayılarının toplamı172 (5 yayında bildirilmiş)
Bildirilen toplam lezyon1.213 (70 yayında)
Kullanılan cihazlar (cihaz adı bildiren 112 yayın)Onkodisruptor (20) · Cliniporator (19) · BTX ECM830 (13) · Chemopulse (7) · LC BK-100 (4) · Chemipulse III (4)
Taşınan ajan ve yol (ajan bildiren 145 yayın)bleomisin · intravenöz (66) · sisplatin · intratümöral (22) · bleomisin · intratümöral (16) · bleomisin · hem intravenöz hem intratümöral (9) · plazmid DNA · intratümöral (9) · bleomisin (7)
Erişim yolu (123 yayın bildiriyor)yüzeyel transkutanöz (47) · perkütan (45) · açık cerrahi (21) · intraoperatif (7) · endoskopik (2)
Görüntüleme kılavuzluğu (81 yayın bildiriyor)doğrudan görüş (59) · ultrason (14) · bilgisayarlı tomografi (8) · manyetik rezonans (3) · endoskopi (2)
Yanıt ölçütü (7 yayın bildiriyor)histolojik (3) · RECIST (2) · klinik muayene (1) · diğer (1)
Kombinasyon tedavisi (97 yayın bildiriyor)sistemik kemoterapi (49) · diğer kombinasyon (29) · cerrahi (28) · diğer immünoterapi (21) · hedefe yönelik tedavi (3)
Tekrar tedavi bildiren yayın95 / 126 yayın (31 yayın bu bilgiyi bildirmiyor)
Alan şiddeti200–15000 V/cm (97 kayıt, ortanca 1200)
Uygulanan gerilim110–2250 V (19 kayıt, ortanca 910)
Darbe sayısı2–800 (109 kayıt, ortanca 8)
Darbe süresi0.015–100000 µs (115 kayıt, ortanca 100)

Toplamlar benzersiz hasta sayısı değildir: aynı kohort birden fazla yayında raporlanmış olabilir.

Yönteme Göre Literatür Durumu

Klinik yöntem başına yayın sayısı, klinik ve preklinik dağılım, literatür hacmi ve yayın aralığı. Sayfa girişindeki rozet yalnızca ECT kaydını özetler; yöntem ayrımının tamamı buradadır.

Elektrokemoterapi (ECT)

122yayın kaydı
26klinik yayın kaydı
80preklinik yayın kaydı

Keşifsel / düşük hacimli literatüreşik 2/122 kayıt

Bu sayının klinik ve preklinik dağılımı: klinik 0, preklinik 1.

1997–2026

İrreversible elektroporasyon (IRE)

4yayın kaydı
0klinik yayın kaydı
4preklinik yayın kaydı

Keşifsel / düşük hacimli literatüreşik 0/4 kayıt

Bu yöntemin hiçbir kaydı hacim etiketine girmemiştir.

2015–2024

Kalsiyum elektroporasyonu

4yayın kaydı
0klinik yayın kaydı
4preklinik yayın kaydı

Keşifsel / düşük hacimli literatüreşik 0/4 kayıt

Bu yöntemin hiçbir kaydı hacim etiketine girmemiştir.

2019–2026

Gen elektrotransferi

18yayın kaydı
1klinik yayın kaydı
14preklinik yayın kaydı

Keşifsel / düşük hacimli literatüreşik 3/18 kayıt

Bu sayının klinik ve preklinik dağılımı: klinik 0, preklinik 2.

2011–2026

Diğer elektroporasyon uygulamaları

7yayın kaydı
0klinik yayın kaydı
3preklinik yayın kaydı

Bu küme tek bir klinik yöntemi adlandırmaz; literatür hacmi atanmaz.

2009–2024

Yöntemi belirlenmemiş kayıtlar

3yayın kaydı
0klinik yayın kaydı
2preklinik yayın kaydı

Bu küme tek bir klinik yöntemi adlandırmaz; literatür hacmi atanmaz.

2013–2025

Özetlerde Anılan Mekanizmalar

Rakam, mekanizma adının geçtiği özet sayısıdır. Bir mekanizmanın anılması, o çalışmada gösterildiği anlamına gelmez.

Bleomisin Hücre İçi Birikiminin Artması 71 Sisplatin Hücre İçi Birikiminin Artması 37 Kas Kasılması ve Anestezi Gereksinimi 23 Gen Elektrotransferi (Plazmid DNA) 22 İnterlökin-12 Aracılı İmmün Uyarım 18 Elektrot Geometrisi ve Yerleşimi 16 Reversible Membran Permeabilizasyonu 16 Sistemik / Abskopal İmmün Yanıt 14 Nekroz ve Nekroptoz 13 Darbe Parametrelerinin Optimizasyonu 12 Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu 8 Apoptoz İndüksiyonu 8

Çalışma Tipi Dağılımı

Yüzde, alanın tamamındaki payı verir.

Çalışma tipiYayınBu alandaki payı
Vaka Raporu27
%17
Kılavuz / Uzlaşı1
<%1
Derleme19
%12
Hayvan Çalışması105
%66
İn Siliko / Modelleme2
%1
Editöryal / Mektup2
%1
Düzeltme / Erratum2
%1

Yayın Tablosu

158 yayın kaydı, çalışma tasarımına göre sıralanmıştır. Başlığa tıklayarak künye, mekanizma ve tam özet çekmecesini açabilirsiniz.

Sınıflandırmalar otomatik üretilir ve tekil kayıtlarda hata içerebilir. Metodoloji

158 yayın kaydı gösteriliyor

RejimYayınYılÇalışma tipiModelMekanizmaHasta / lezyonCihazAjan ve yolBildirilen sonuçÖzet
ECT
Maggi et al · Front Vet Sci
2026Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi– / 2Cliniporator VITAEbleomisin · intravenöztümör hacmi değişimi 81% (1 lezyon)Electrochemotherapy is a local anticancer treatment used for selected cutaneous tumors, but its application in veterinary medicine for nasal neoplasms is only rarely reported. Two dogs with …
ECT
Peña et al · Vet Ophthalmol
2026Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Reversible Membran Permeabilizasyonu– / 2Cavity electrode (Leroy Biotech)bleomisin · hem intravenöz hem intratümöraltam yanıt 100% (2 hasta)Background: Squamous cell carcinoma (SCC) is one of the most common malignant eyelid tumors in cats, especially in white-haired individuals chronically exposed to sunlight. Electrochemothera…
Gen ET
Lampreht Tratar et al · Front Vet Sci
2026Vaka RaporuHayvan (İn Vivo)Elektrot Geometrisi ve Yerleşimi, İnterlökin-12 Aracılı İmmün Uyarım– / 1Cliniporatorsisplatin · intratümöraltam yanıt 180 gün (1 lezyon)Electrochemotherapy (ECT) combined with gene electrotransfer of interleukin-12 (IL-12 GET) has shown promising results in the treatment of canine mast cell tumors (MCTs). However, when tumor…
ECT
Akiyoshi et al · Front Vet Sci
2026Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Elektrik Alan Dağılımı ve Modellemesi– / 1ELECTROVET EZbleomisin · intravenözgenel sağkalım 120 gün (1 hasta)A 14-year-old spayed female Persian cat with lingual feline oral squamous cell carcinoma (FOSCC) was treated with bleomycin-based electrochemotherapy (ECT), resulting in sustained preservati…
ECT
Ruanova et al · Open Vet J
2025Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–Onkodisruptorbleomisin · intravenöztam yanıt 4 adet (4 hasta)Background: Cutaneous mast cell tumor (MCT) is one of the most common skin neoplasms in cats and typically exhibits clinically benign behavior. Multiple MCTs, recurrent tumors, or infiltrate…
ECT
Andrade et al · Braz J Vet Med
2024Vaka RaporuHayvan (İn Vivo)Nekroz ve Nekroptoz– / 1ePOREbleomisin · intravenöz–An 8-year-old male rabbit ( Oryctolagus cuniculus ) presented with a subcutaneous mass in the proximal region of the fourth and accessory digit measuring 5.5 x 3.5 x 5.2cm. The mass was non-…
ECT
Larsen et al · Vet Ophthalmol
2024Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi– / 2CLINIVET VEP02bleomisin · intratümöraltam yanıt 100% (2 lezyon)Objective: To describe the procedure and outcome of electrochemotherapy (ECT) with bleomycin as a first-line treatment for bilateral ocular surface squamous neoplasia (OSSN) in the eye of a …
ECT
Pimentel et al · Top Companion Anim Med
2024Vaka RaporuHayvan (İn Vivo)––VetCP125bleomisin · intravenözgenel sağkalım 707 günApocrine sweat gland adenocarcinoma (ASGAC) is a rare skin carcinoma in cats. In some cases, this tumor occurs in anatomical sites of challenging wide surgical resection, which increases the…
ECT
Salmoral et al · JFMS Open Rep
2024Vaka RaporuHayvan (İn Vivo)Kalsiyum Elektroporasyonu ve ATP Tükenmesi–Onkodisruptorbleomisin · intravenöztam yanıt 3 adet (3 hasta)Case series summary: Malignant basal cell tumours may be seen on or near the nasal planum in cats, and include basal cell carcinomas, which are common, and basosquamous carcinomas, which are…
ECT
Sena et al · Front Vet Sci
2024Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 5VETCP 125, ePOREbleomisin · intravenöztam yanıt 1 adet (1 hasta)Feline histiocytic diseases are uncommon and rarely reported. Feline progressive histiocytosis (FPH) is the most common histiocytic disease in cats, predominantly affecting middle-aged anima…
ECT
Dos Santos da Luz et al · Vet Res Forum
2023Vaka RaporuHayvan (İn Vivo)Reversible Membran Permeabilizasyonu– / 1VetCP 125bleomisin · intravenöz–Melanocytoma and malignant melanoma are the most typical eye tumors in dogs and cats. Due to the presence of melanin, the general appearance is often highly pigmented in a nodular formation …
ECT
Little et al · JFMS Open Rep
2022Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 1Onkodisruptorbleomisin · intravenöz–Case summary: A 4-year-old domestic shorthair cat presented to North Downs Specialist Referrals for treatment of a 7 mm melanoma of the nasal planum. Two treatments of electrochemotherapy us…
ECT
Dos Anjos et al · Vet Res Forum
2020Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması–Onkodisruptorbleomisin · intravenöz–Electroporation is a technique that increases the uptake of chemotherapeutic drugs by tumors. Electrochemotherapy (ECT) has been successfully used to treat solid tumors. Recently, novel appl…
ECT
Martins Taques et al · Artif Organs
2020Vaka RaporuHayvan (İn Vivo)Elektrot Geometrisi ve Yerleşimi, Elektrik Alan Dağılımı ve Modellemesi– / 1VetCp 125bleomisin · intravenöz–Osteosarcoma is a bone cancer considered rare to humans, but common in dogs. Dogs and humans share genetic homology and environmental risk factors. Improving the treatment of osteosarcoma in…
ECT
Santos dos Anjos et al · Top Companion Anim Med
2020Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması––– · hem intravenöz hem intratümöral–Plasma cell tumors can occur as solitary collections referred as extramedullary plasmocytoma (EMP). The present report describes four cases of EMP treated with a local nonthermal ablative ap…
ECT
Tunikowska et al · Animals (Basel)
2020Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Nekroz ve Nekroptoz–PPG-20 generatorbleomisin · intratümöraltam yanıt 1 adet (1 hayvan)Background: The aim of this study was to present the first domestic animal trial of nanosecond electroporation with chemotherapy and CO 2 laser surgery. Methods: sixteen-year-old domestic ca…
ECT
Racnik et al · Journal of Exotic Pet Medicine
2019Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması– / 1Cliniporatorbleomisin · intratümöraltam yanıt 100% (1 lezyon)A 12-year-old female cockatiel (Nymphicus hollandicus) was presented with a squamous cell carcinoma involving the uropygial gland. Electrochemotherapy (ECT) as a minimally invasive treatment…
ECT
Torrigiani et al · Vet Comp Oncol
2019Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 54Cytopulse PA4000, Cytopulse Oncovetbleomisin · intravenözgenel sağkalım 75% (4 lezyon)Canine soft tissue sarcomas (STSs) are locally invasive mesenchymal neoplasms. Electrochemotherapy (ECT) is an antitumour local ablative treatment that uses electric pulses to enhance the in…
ECT
Spugnini et al · Open Vet J
2017Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi– / 1Onkodisruptorbleomisin · intravenöztümör hacmi değişimi 50% (1 hasta)A twelve-year-old male castrated domestic shorthair cat was presented for rapidly progressing respiratory distress. The cat was depressed, tachypneic and moderately responsive. Ultrasonograp…
ECT
Spugnini et al · Open Vet J
2016Vaka RaporuHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması– / 1Onkodisruptorsisplatin · intratümöralhastalıksız sağkalım 12 ay (1 hasta)An eleven-year-old stallion was referred for adjuvant treatment of an incompletely excised, recurring penile fibrosarcoma. The horse was bright, alert and responsive with a 15 x 12 cm ulcera…
ECT
Spugnini et al · Can Vet J
2013Vaka RaporuHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması, Bleomisin Hücre İçi Birikiminin Artması– / 1Chemipulse IIIdiğer · hem intravenöz hem intratümöraltam yanıt 1 ay (1 hasta)This paper reports the clinical findings, histopathology, and clinical outcome of a rare case of aponeurotic fibromatosis in a dog. The dog was treated with 4 courses of electrochemotherapy …
ECT
Spugnini et al · J Small Anim Pract
2010Vaka RaporuHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması–Chemopulse electroporator, Chemopulsesisplatin · intratümöraltam yanıt 100% (1 hayvan)A 13-year-old male neutered cat was presented for the sudden growth of two nodular lesions close to the upper eyelid of both eyes. Fine-needle aspiration cytology was suggestive of mesenchym…
ECT
Spugnini et al · In Vivo
2008Vaka RaporuHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması– / 1–sisplatin · intratümöraltam yanıt 18 ay (1 hasta)Canine anal sac gland carcinoma (ASGC) is a frequently described neoplasm that is highly aggressive and can frequently lead to metastatic spread. In this paper, we describe the successful tr…
ECT
Spugnini et al · In Vivo
2008Vaka RaporuHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması––sisplatin–Electrochemotherapy is gaining popularity for the treatment of malignancies of companion animals due to its efficacy and low cost. In this paper, we describe the successful treatment of a re…
ECT
Spugnini et al · Vet J
2008Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması– / 1modified calliper electrodesbleomisin · intratümöraltam yanıt 1 adet (1 hasta)An 8-year-old male castrated cat was referred for sudden onset of lameness. Physical examination revealed a 1x2x1cm mass originating from a footpad of the right hind leg. A diagnosis of gang…
ECT
Spugnini et al · Vet Rec
2008Vaka RaporuHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 1–bleomisin · intratümöraltam yanıt 1 gün (1 lezyon)Short Communications Surgery and electrochemotherapy of a high-grade soft tissue sarcoma in a dog E. P. Spugnini, B. Vincenzi, G. Betti, F. Cordahi, I. Dotsinsky, N. Mudrov, G. Citro, A. Bal…
ECT
Spugnini et al · In Vivo
2007Vaka RaporuHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt– / 1–sisplatin · intratümöraltümör hacmi değişimi 50% (1 lezyon)Canine anal melanoma is an aggressive neoplasm that rapidly leads to constipation in dogs, thus mimicking the behavior of their human counterpart. In this paper, the successful local palliat…
ECT
Tellado et al · Front Vet Sci
2022Kılavuz / UzlaşıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması––bleomisin · intravenöz–Electrochemotherapy (ECT) consists in the application of electric pulses to increase chemotherapeutic drug intake (bleomycin, cisplatin, or calcium) into the tumor cells. It has become a ver…
ECT
Ertürk ve Özsoy · –
2026DerlemeHayvan (İn Vivo)–––bleomisin · intratümöraltam yanıt 100% (1 hasta)( ) * Corresponding author: Esma Hande Ertürk Phone: +90 535 015 23 61 E-mail: esmahande.sevis@ogr.iuc.edu.tr How to cite this article? Ertürk EH, Özsoy S: Electrochemotherapy as an Emerging…
ECT
Ramos et al · Vet Comp Oncol
2024DerlemeHayvan (İn Vivo)–––– · hem intravenöz hem intratümöral–Electrochemotherapy (ECT) is a treatment modality that combines the electroporation of cell membranes with chemotherapy to facilitate the transport of non-permeant molecules into cells. Seve…
Diğer EP
Spugnini et al · Cancers (Basel)
2024DerlemeLiteratür AnaliziReversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü––––Electroporation (EP) is a broadly accepted procedure that, through the application of electric pulses with appropriate amplitudes and waveforms, promotes the delivery of anticancer molecules…
Diğer EP
Pazzi et al · Vet Sci
2022DerlemeLiteratür Analizi–––bleomisin · intravenözgenel sağkalım 225 gün (67 hasta)Critical appraisal of the available literature for the treatment of canine oral malignant melanoma (OMM) is lacking. This critical review aimed to evaluate the current literature and provide…
Gen ET
Maglietti et al · Vaccines (Basel)
2020DerlemeLiteratür AnaliziGen Elektrotransferi (Plazmid DNA), Reversible Membran Permeabilizasyonu––bleomisin–Electroporation is a technology that increases cell membrane permeability by the application of electric pulses. Electrochemotherapy (ECT), the best-known application of electroporation, is …
Diğer EP
Nemec et al · Front Vet Sci
2020DerlemeLiteratür AnaliziGen Elektrotransferi (Plazmid DNA)––bleomisin · intravenöz–Electroporation is a method of inducing an increase in permeability of the cell membrane through the application of an electric field and can be used as a delivery method for introducing mol…
ECT
Rangel et al · Austral j. vet. sci.
2019DerlemeHayvan (İn Vivo)Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu––bleomisin–Electrochemotherapy (ECT) is a technique that combines chemotherapy with local application of specific electric pulses with the aim of increasing the permeability of the plasma membrane in a…
ECT
Tunikowska J, Kulbacka J, Michel O, Kiełbowicz Z · Weterynaria w Praktyce
2018DerlemebelirsizAntivasküler Etki ve Damar Yıkımı––bleomisin · hem intravenöz hem intratümöral–The modern treatment of veterinary oncologic patients often relies on polytherapy which combines standard surgical excision with additional treatment modality. Electrochemotherapy (ECT) is t…
Belirlenmedi
Cramp P · –
2017DerlemeHayvan (İn Vivo)–––sisplatin–Melanomas are a well-known problem of the grey horse population, with grey horses having an 80% probability of developing melanomas in their life [1]. There seems to be no sex predilection, …
ECT
Goanta et al · AGROLIFE
2017DerlemeHayvan (İn Vivo)Kas Kasılması ve Anestezi Gereksinimi, Bleomisin Hücre İçi Birikiminin Artması––bleomisin · hem intravenöz hem intratümöral–Electrochemotherapy (ECT) is a recent anticancer treatment used for solid tumours in which square wave electric pulses are combined with a chemotherapeutic drug administered either intraveno…
Gen ET
Pavlin et al · Handbook of Electroporation
2017DerlemeLiteratür AnaliziGen Elektrotransferi (Plazmid DNA), İnterlökin-12 Aracılı İmmün Uyarım––bleomisin · intratümöraltam yanıt 100%Veterinary medicine has become an important translational bridge from in vitro and preclinical studies to human medicine, offering invaluable model for research in naturally occurring diseas…
ECT
Tozon et al · Handbook of Electroporation
2017DerlemeLiteratür AnaliziSisplatin Hücre İçi Birikiminin Artması, Bleomisin Hücre İçi Birikiminin Artması––bleomisin · intravenöznesnel yanıt 79%In veterinary oncology, the clinical studies on electrochemotherapy are not numerous. Electrochemotherapy in veterinary oncology is used with two chemotherapeutic drugs, cisplatin and bleomy…
Diğer EP
Impellizeri et al · Vet J
2016DerlemeHayvan (İn Vivo)–––bleomisin · intravenöz–Cancer treatments in veterinary medicine continue to evolve beyond the established standard therapies of surgery, chemotherapy and radiation therapy. New technologies in cancer therapy inclu…
ECT
Spugnini et al · J Cell Physiol
2016DerlemeHayvan (İn Vivo)–––––Electrochemotherapy (ECT) is a medical strategy that allows an increased efficacy of chemotherapy agents after the application of permeabilizing electric pulses having appropriate characteri…
ECT
Spugnini et al · Curr Cancer Drug Targets
2015DerlemeHayvan (İn Vivo)–––bleomisin · intratümöral–Tumor microenvironment is one of the major obstacles to the efficacy of chemotherapy in cancer patients. The abnormal blood flow within the tumor results in uneven drug distribution. Electro…
Gen ET
Pavlin · J Transl Med
2012DerlemeHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)––plazmid DNA · intratümöral–The use of large animals as an experimental model for novel treatment techniques has many advantages over the use of laboratory animals, so veterinary medicine is becoming an increasingly im…
ECT
Spugnini et al · Future Oncol
2012DerlemeHayvan (İn Vivo)–––bleomisin · hem intravenöz hem intratümöral–Electrochemotherapy is a tumor treatment that adapts the systemic or local delivery of anticancer drugs by the application of permeabilizing electric pulses with appropriate amplitude and wa…
ECT
Spugnini et al · J Exp Clin Cancer Res
2009DerlemeHayvan (İn Vivo)–––bleomisin–The treatment of soft tissue tumors needs the coordinated adoption of surgery with radiation therapy and eventually, chemotherapy. The radiation therapy (delivered with a linear accelerator)…
ECT
Cemazar et al · J Vet Intern Med
2008DerlemeHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, Bleomisin Hücre İçi Birikiminin Artması––diğer · hem intravenöz hem intratümöral–Electropermeabilization is a method that uses electric field pulses to induce an electrically mediated reorganization of the plasma membrane of cells. Electrochemotherapy combines local or s…
ECT
Tozon Mask et al · BMC Vet Res
2026Hayvan ÇalışmasıHayvan (İn Vivo)–– / 138Cliniporatorbleomisin · intravenöztam yanıt 74% (110 lezyon)Electrochemotherapy (ECT) is a local ablative treatment and in veterinary oncology, evidence supporting ECT efficacy is mainly derived from case reports and small case series, underscoring t…
ECT
Franchini et al · –
2026Hayvan ÇalışmasıHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, Ekstraselüler Matriks ve Doku İskeletinin Korunması–Onkodisruptorbleomisin · intravenözgenel sağkalım 1012 gün (39 hasta)Tumors are complex microenvironments in which uncontrolled cell proliferation alters biochemical pathways as well as the physical and electrical properties of tissues. Electrochemotherapy (E…
ECT
Franchini et al · Sci Rep
2026Hayvan ÇalışmasıHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, Ekstraselüler Matriks ve Doku İskeletinin Korunması– / 39Onkodisruptorbleomisin · intravenözgenel sağkalım 1012 gün (39 hasta)Tumors are complex microenvironments in which uncontrolled cell proliferation alters biochemical pathways as well as the physical and electrical properties of tissues. Electrochemotherapy (E…
ECT
Franchini et al · Vet Comp Oncol
2026Hayvan ÇalışmasıHayvan (İn Vivo)Nekroz ve Nekroptoz–Onkodisruptorbleomisin · intravenözgenel sağkalım 640 gün (18 hasta)Electrochemotherapy is increasingly used as a locoregional treatment for feline squamous cell carcinoma, but its role in advanced nasal planum disease remains poorly defined. This retrospect…
ECT
Frigerio et al · Case Rep Vet Med
2026Hayvan ÇalışmasıHayvan (İn Vivo)–– / 1ePOREbleomisin · intravenözlokal nüks 0 adet (1 hasta)Squamous cell carcinoma (SCC) is a malignant epithelial neoplasm commonly affecting the skin and oral cavity of dogs, whereas laryngeal involvement is considered rare. Neoplasms arising in t…
ECT
Holanda et al · Vet J
2026Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Nekroz ve Nekroptoz35–––Electrochemotherapy (ECT) has emerged as a valuable therapeutic option for feline cutaneous squamous cell carcinoma (SCC). However, the influence of clinicopathological variables on treatmen…
Kalsiyum EP
Holst et al · J Am Vet Med Assoc
2026Hayvan ÇalışmasıHayvan (İn Vivo)Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Kas Kasılması ve Anestezi Gereksinimi– / 4Cliniporator, linear array probe N-20-4Bkalsiyum klorür · intratümöral–Objective: To evaluate the clinical outcome of calcium electroporation in treating canine superficial solid tumors using 1 or 2 treatment sessions and to assess the associated adverse events…
ECT
D LESCAI, B BAROIU, A COTIȚOSU, A CRISTEA · Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine
2026Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 1Leroy Biotech veterinary electroporation devicebleomisin · hem intravenöz hem intratümöraltam yanıt 1 adet (1 lezyon)Mast cell tumors (MCT) in anatomically complex periocular regions of cats often preclude curative surgery. Electrochemotherapy (ECT) offers local control while preserving function. A 17-year…
Gen ET
Lisjak et al · Vet Sci
2026Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)––bleomisin · intravenöztam yanıt 16 adet (24 hasta)Cancer is a major health concern, with its incidence rate continuing to increase. There is growing interest in the microbiota and its role in carcinogenesis, as it significantly influences p…
ECT
Martins et al · Braz J Vet Med
2026Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 1Onkodisruptorbleomisin · intravenöztam yanıt 1 adet (1 hasta)Multilobular Bone Tumor (MBT) is a rare, slow-growing, and locally invasive neoplasm in middle-aged to older dogs, occurring predominantly in flat bones of the skull, pelvis, or ribs. This w…
ECT
Milevoj et al · Vet Q
2026Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu–Cliniporatorbleomisin · intravenöztam yanıt 6 adet (14 lezyon)Bleomycin (BLM) is a cytotoxic antibiotic used in veterinary oncology, primarily in electrochemotherapy (ECT), a local ablative therapy where electric pulses increase drug uptake in tumours.…
ECT
Ojeda et al · J Vet Intern Med
2026Hayvan ÇalışmasıHayvan (İn Vivo)––Cellporator VetCP 125bleomisin · intravenöz–Background Mast cell tumors (MCTs) in dogs pose therapeutic challenges that vary with histopathological grade. Hypothesis/objectives Electrochemotherapy (ECT) alone would result in a clinica…
ECT
Regadas et al · Top Companion Anim Med
2026Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–BK100bleomisin · intravenöz–In cats, the high incidence of malignant mammary neoplasms with elevated rates of metastasis and recurrence underscores the need for more effective therapies to prevent disease progression. …
ECT
Silva et al · Arq. Bras. Med. Vet. Zootec.
2026Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–ELECTROvet EZ®bleomisin · intravenözlokal nüks 35% (20 hasta)Feline application sarcoma (FAS) is a mesenchymal malignancy associated with chronic inflammation caused by subcutaneous or intramuscular applications. Surgical resection is the most recomme…
ECT
Sofia et al · Vet Comp Oncol
2026Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu–Onkodisruptorbleomisin · intravenözlokal nüks 68.2% (22 hasta)The predominant challenge in canine soft tissue sarcomas (STSs) is achieving local tumour control, for which surgical excision remains the standard treatment. When complete margins are not a…
ECT
Spadari et al · Vet Sci
2026Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması– / 23ELECTRO vet S13, CLINIVETsisplatin · intratümörallokal kontrol 69.6% (23 lezyon)Despite the wide range of therapeutic options currently available for equine sarcoids, recurrence of these lesions remains a major clinical challenge. Consequently, the identification of eff…
ECT
Ciccarelli et al · Sci Rep
2025Hayvan ÇalışmasıHayvan (İn Vivo)Nekroz ve Nekroptoz21Onkodisruptorbleomisin · intravenöz–Electrochemotherapy (ECT) presents an effective alternative for local tumor management, particularly valuable when surgery is not feasible. The side effects are generally mild, including loc…
ECT
Amato et al · Open Vet J
2025Hayvan ÇalışmasıHayvan (İn Vivo)Sistemik / Abskopal İmmün Yanıt–Onkodisruptorbleomisin · intravenözgenel sağkalım 70 gün (9 hasta)Background: Canine prostatic carcinoma (PC) is an uncommon neoplasia characterized by aggressive biological behavior. Treatment options include surgery (partial or total prostatectomy), radi…
Gen ET
Camerino et al · Vet Q
2025Hayvan ÇalışmasıHayvan (İn Vivo)Gen Elektrotransferi (Plazmid DNA)–Cliniporatorplazmid DNA · intratümöralgenel sağkalım 37.7 ay (80 hasta)Canine oral malignant melanoma (OMM) is an aggressive, spontaneously occurring tumor carrying a poor to guarded prognosis and relatively limited therapeutic strategies. In this landscape, ch…
ECT
Costa et al · Cad. Pedagógico
2025Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt– / 2–bleomisin · intravenöz–Canine cutaneous mast cell tumors represent a significant clinical challenge due to the wide variability in biological behavior and the risk of recurrence or metastasis, requiring individual…
ECT
Foo et al · J Feline Med Surg
2025Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–Electrovet S13bleomisin · intravenöztam yanıt 15 adet (23 hasta)ObjectivesFeline cutaneous squamous cell carcinoma (cSCC) is a malignant tumour arising from squamous epithelium and accounts for 15% of all skin tumours, commonly involving the nasal planum…
ECT
Machado et al · Arq. Bras. Med. Vet. Zootec.
2025Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt– / 1–bleomisin · intravenöztam yanıt 3 adet (4 hasta)Squamous cell carcinoma is a common neoplasm in felines that mainly affects the face, an area that is difficult to treat. Due to its high frequency, it is a challenge in the Oncology Clinic.…
ECT
Peña et al · Vet Record Case Reports
2025Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 1Electrovet EZ V3.0bleomisin · intravenöztam yanıt 1 adet (1 hasta)In recent years, electrochemotherapy has gained relevance in veterinary oncology for the treatment of locally invasive superficial tumours in dogs, such as mast cell tumours, perianal neopla…
Belirlenmedi
Rodrigues Soares et al · RVZ
2025Hayvan ÇalışmasıHayvan (İn Vivo)–– / 1VetCPbleomisin · intravenöz–O neurofibrossarcoma é descrito como um sarcoma de tecidos moles, caracterizado por um tumor maligno originado das bainhas de nervos periféricos. Atendeu-se no Hospital Veterinário da Univer…
Gen ET
Vilfan et al · Animals (Basel)
2024Hayvan ÇalışmasıHayvan (İn Vivo)Nekroz ve Nekroptoz, İnterlökin-12 Aracılı İmmün Uyarım48 / 86Cliniporatorsisplatin–Electrochemotherapy (ECT) in combination with the gene electrotransfer of interleukin 12 (IL-12 GET) has been successfully used in veterinary medicine for the treatment of mast cell tumours …
ECT
Diop et al · Vet Comp Oncol
2024Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–ELECTROvetEZdiğer · hem intravenöz hem intratümöralgenel sağkalım 669 gün (44 hasta)Electrochemotherapy (ECT) with intravenous (IV) and/or intratumoral (IT) bleomycin has shown considerable efficacy in the treatment of non-resectable feline cutaneous squamous cell carcinoma…
ECT
Ferrer-Jorda et al · J Feline Med Surg
2024Hayvan ÇalışmasıHayvan (İn Vivo)––Onkodisruptorbleomisin · intravenöztam yanıt 19 adet (21 hasta)Objectives: Squamous cell carcinoma (SCC) is the most common tumour in the nasal planum of cats. Surgery has traditionally been the treatment of choice but might not be feasible in locally a…
ECT
dos Santos et al · Front Vet Sci
2024Hayvan ÇalışmasıHayvan (İn Vivo)Sistemik / Abskopal İmmün Yanıt– / 30VETCP 125bleomisin · intravenöz–Introduction: Squamous cell carcinoma (SCC) is a malignant neoplasm that accounts for approximately 15-25% and 70-80% of all feline cutaneous and oral tumors, respectively. Similar to that i…
IRE
Hay · Biomedicines
2024Hayvan ÇalışmasıHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü– / 7custom built H-FIRE generator, AngioDynamics bipolar electrodes–progresyonsuz sağkalım 100% (5 hasta)In this study, the feasibility of treating canine primary lung tumors with high-frequency irreversible electroporation (H-FIRE) was investigated as a novel lung cancer treatment option. H-FI…
IRE
Fesmire · Front Vet Sci
2024Hayvan ÇalışmasıHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü– / 45––tam yanıt 8 adet (10 lezyon)Introduction: Integrated time nanosecond pulse irreversible electroporation (INSPIRE) is a novel tumor ablation modality that employs high voltage, alternating polarity waveforms to induce c…
ECT
Rangel et al · –
2023Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 21VETCP 125bleomisin · intravenöznesnel yanıt 86% (21 hasta)Local treatment of canine urothelial carcinoma (UC) of the bladder is a challenge. More than 90% of cases arise as muscle-invasive tumors, with more than 50% developing on bladder sites with…
ECT
Freitas et al · RSD
2023Hayvan ÇalışmasıHayvan (İn Vivo)–– / 1–diğer · intravenözlokal nüks 0 adet (1 hasta)Squamous cell carcinoma (SCC) is a malignant epithelial neoplasm derived from keratinocytes, commonly preceded by actinic (solar) keratosis, with unclear etiology but associated with host an…
ECT
Gokulakrishnan et al · IJAR
2023Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması– / 12ELECTRO vet S13diğer · intratümöraltam yanıt 6 adet (6 hasta)Background: Mammary neoplasms are the most common tumours in the bitch. Even though surgery remained the treatment of choice for mammary gland tumours except those with inflammatory carcinom…
Gen ET
Lampreht Tratar et al · Int Immunopharmacol
2023Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)––sisplatin · intratümöralnesnel yanıt 67% (27 lezyon)The combined treatment of electrochemotherapy (ECT) and interleukin-12 (IL-12) gene electrotransfer (GET) has already been used in clinical studies in dogs to treat various histological type…
ECT
Ribeiro et al · Pesq. Vet. Bras.
2023Hayvan ÇalışmasıHayvan (İn Vivo)Apoptoz İndüksiyonu– / 18LC BK100, LC BK100 electroporatorbleomisin · intravenöztam yanıt 8 adet (13 hasta): Determining cell proliferation rates and tumor apoptosis through immunohistochemistry allows the evaluation of the biological behavior of the tumor, optimizing the patient’s clinical cours…
ECT
de Castro Cunha et al · Vet Comp Oncol
2023Hayvan ÇalışmasıHayvan (İn Vivo)––VetCP 125bleomisin · intravenöznesnel yanıt 90.9% (33 hasta)Squamous cell carcinoma (SCC) is an important malignancy in dogs, due to its incidence and clinical presentation, which can be of locally aggressive single or multiple lesions with a metasta…
ECT
Doneley et al · Journal of Exotic Pet Medicine
2022Hayvan ÇalışmasıHücre KültürüSisplatin Hücre İçi Birikiminin Artması, Bleomisin Hücre İçi Birikiminin Artması– / 1ElectroVET EZsisplatin · intratümöraltam yanıt 1 adet (1 lezyon)Background: Bearded dragons (Pogona vitticeps) are one of the most popular reptile pets globally. As their longevity increases with better care and nutrition, conditions common to many older…
ECT
Moretti et al · Front Vet Sci
2022Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–Cliniporatorbleomisin · intravenöz–Electrochemotherapy (ECT) is a highly developed treatment for many solid tumours that provides good local control in 80% of neoplasms in dogs. ECT can be used to treat different types of tum…
ECT
Tellado et al · Cancer Drug Resist
2022Hayvan ÇalışmasıHayvan (İn Vivo)Elektrot Geometrisi ve Yerleşimi, Bleomisin Hücre İçi Birikiminin Artması–EPV-200bleomisin · intravenöznesnel yanıt 80% (15 hasta)Aim: Cutaneous squamous cell carcinoma (cSCC) is a common disease in patients exposed to UV-light and human papillomavirus. Electrochemotherapy, a well-established treatment modality with mi…
ECT
Dos Anjos et al · Life (Basel)
2021Hayvan ÇalışmasıHayvan (İn Vivo)–– / 18Electroporator LC BK-100bleomisin · intravenöz–Canine cutaneous squamous cell carcinoma (SCC) is the most common type of skin cancer in tropical countries and is generally associated with exposure to solar ultraviolet light. It has a low…
ECT
Valenti et al · Open Vet J
2021Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması–Onkodisruptorbleomisin · hem intravenöz hem intratümöralnesnel yanıt 60% (10 hasta)Background: Electrochemotherapy (ECT) combines the administration of anticancer drugs with the delivery of electric pulses, thus increasing the drug uptake through the cell membranes, result…
ECT
Brloznik et al · Front Vet Sci
2021Hayvan ÇalışmasıHayvan (İn Vivo)Gen Elektrotransferi (Plazmid DNA), İnterlökin-12 Aracılı İmmün Uyarım– / 12–bleomisin · intravenöztam yanıt 7 adet (12 lezyon)Electrochemotherapy (ECT) and/or gene electrotransfer of plasmid DNA encoding interleukin-12 (GET pIL-12) are effective treatments for canine cutaneous, subcutaneous, and maxillofacial tumor…
Gen ET
Pavlin et al · SVR
2021Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)–Cliniporatorbleomisin · intravenöz–A 15-year- old male castrated English setter was presented for evaluation of a rapidly growing oral mass. Patient’s history was otherwise unremarkable, except of moderate proteinuria of 5 ye…
ECT
Simčič et al · Vet Sci
2021Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Darbe Parametrelerinin Optimizasyonu61–––Feline squamous cell carcinoma (SCC) is currently treated with surgery, radiation therapy and electrochemotherapy (ECT). Both the efficacy and/or safety of ECT were evaluated as a sole thera…
ECT
Spugnini et al · Open Vet J
2021Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması, Kas Kasılması ve Anestezi Gereksinimi– / 16Onkodisruptorsisplatin · intratümöral–Background: Electrochemotherapy (ECT) promotes the increased uptake of antitumor agents through the administration of permeabilizing electric pulses, thus enhancing chemotherapy effectivenes…
ECT
Spugnini et al · Open Vet J
2020Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması–Onkodisruptorbleomisin · intravenözgenel sağkalım 985 günBackground: fFeline injection-site sarcomas (FISSs) are mesenchymal tumors that can occur in cats after injections of different medical agents and are easily prone to recurrence. Aim: The ai…
ECT
Dos Anjos et al · Sci Rep
2020Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 66Onkodisruptorbleomisin · intravenöztam yanıt 10 adet (24 lezyon)Cutaneous squamous cell carcinoma (cSCC) is one of the most common skin tumors in cats due to chronic exposure to ultraviolet light. Local treatments such as electrochemotherapy (ECT) promot…
Kalsiyum EP
Frandsen · Animals (Basel)
2020Hayvan ÇalışmasıHayvan (İn Vivo)Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Darbe Parametrelerinin Optimizasyonu– / 32Cliniporatorkalsiyum klorür · intratümöraltam yanıt 22% (27 lezyon)Sarcoids are common equine skin tumors where the risk of recurrence after treatment is high, and better treatment options are warranted. Calcium electroporation is a novel anti-cancer treatm…
Gen ET
Milevoj et al · Vet Med Sci
2020Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)––diğeryaşam kalitesi 7.4 skor (44 hasta)The aim of this study was to evaluate the owners' perception of health-related quality of life (HRQoL) of dogs after treatment with electrochemotherapy (ECT) alone or combined with interleuk…
ECT
Tellado et al · Radiol Oncol
2020Hayvan ÇalışmasıHayvan (İn Vivo)––BTX ECM830bleomisin · intravenöznesnel yanıt 70.1% (67 hasta)Background Oral malignant melanoma is the most common, but aggressive oral cancer in dogs with poor prognosis. Electrochemotherapy (ECT) has therapeutic potential in such tumors as effective…
ECT
dos Anjos et al · Data Brief
2020Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması–LC-BK100, Onkodisruptorsisplatin · intratümöraltam yanıt 3 adet (4 hasta)Over the past 15 years, lipophobic drugs, such as bleomycin and cisplatin, have been used combined with electroporation, which promotes their uptake through the cell membrane. The present da…
ECT
Boncea et al · Vet Record Case Reports
2019Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması– / 24Electrovet S13sisplatin · intratümöraltam yanıt 100% (24 lezyon)Canine squamous cell carcinoma (cSCC) is the second most common cutaneous neoplasm in dogs. Treatment options are limited. Electrochemotherapy (ECT) has been proposed as an alternative treat…
Kalsiyum EP
Dos Anjos et al · Acta Scientiae. Vet.
2019Hayvan ÇalışmasıHayvan (İn Vivo)Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Nekroz ve Nekroptoz– / 3LC BK-100bleomisin · intravenöztam yanıt 1 adet (3 lezyon)Background: Calcium electroporation (CaEP) is a novel therapeutic treatment that has been studied for cancer due to its selective killing cancer cells by necrosis and danger signals. Besides…
ECT
Dos Anjos et al · Sci Rep
2019Hayvan ÇalışmasıHayvan (İn Vivo)Apoptoz İndüksiyonu– / 18LC BK-100bleomisin · intravenöz–Canine cutaneous squamous cell carcinoma (cSCC) is the most common skin cancer in dogs, and, due to its low metastatic rate, local treatments, such as electrochemotherapy (ECT), promote dise…
Kalsiyum EP
Galant et al · Bioelectrochemistry
2019Hayvan ÇalışmasıHayvan (İn Vivo)Nekroz ve Nekroptoz, Reversible Membran Permeabilizasyonu– / 16Electrovet S13kalsiyum klorür · intratümöral–Electrochemotherapy (ECT) is an anticancer bioelectrochemical therapy where electrical field pulses (electropermeabilization) increase intracellular concentration of antitumor drugs. The pro…
Gen ET
Milevoj et al · Res Vet Sci
2019Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)–Cliniporator, MEAbleomisin · intravenöznesnel yanıt 67% (9 hasta)The aim of this study was to evaluate the safety and efficacy of the combination of electrochemotherapy (ECT) with bleomycin and gene electrotransfer (GET) of plasmid encoding canine interle…
ECT
Moura et al · Revista Brasileira de Higiene e Sanidade Animal
2019Hayvan ÇalışmasıHayvan (İn Vivo)–– / 1–– · intratümöral–O mastocitoma é uma neoplasia de células redondas frequentemente encontrado em cães, correspondendo entre 7% e 21% das neoplasias cutâneas. Este trabalho teve como objetivo relatar as altera…
ECT
Simčič et al · Vet Comp Oncol
2019Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–Cytopulse Oncovet, Cytopulse PA4000bleomisin · intravenöztam yanıt 8 adet (11 hasta)Non-tonsillar squamous cell carcinoma (ntSCC) is a common and locally aggressive oral tumour in dogs. The treatments of choice are currently surgery and radiotherapy. Electrochemotherapy (EC…
ECT
Spugnini et al · Open Vet J
2019Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması–Onkodisruptorbleomisin · hem intravenöz hem intratümöraltam yanıt 26 adet (30 hasta)Electrochemotherapy (ECT) couples the administration of anticancer drugs with the delivery of electric pulses that increase the drug uptake through the cell membranes, thus resulting in an i…
ECT
Tellado et al · –
2019Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–BTX ECM830bleomisin · intravenöznesnel yanıt 100% (11 hasta)Electrochemotherapy is a treatment modality which has been increasingly used in veterinary and human medicine for treating cutaneous and subcutaneous tumors. In this prospective work we eval…
Gen ET
Thalmensi · Oncotarget
2019Hayvan ÇalışmasıHayvan (İn Vivo)Gen Elektrotransferi (Plazmid DNA)–Cliniporator, Agilepulse® in vivo system electroporatorplazmid DNA · intratümöral–Telomerase reverse transcriptase (TERT) is highly expressed in more than 90% of canine cancer cells and low to absent in normal cells. Given that immune tolerance to telomerase is easily bro…
ECT
Anjos et al · –
2018Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Apoptoz İndüksiyonu– / 18LC BK-100diğer · intravenözgenel sağkalım 180 gün (11 hasta)Canine cutaneous squamous cell carcinoma (cSCC) is the most common skin cancer in dogs, and due to its low metastatic rate, local treatments such as electrochemotherapy (ECT) promote disease…
ECT
Dos Anjos et al · Vet Record Case Reports
2018Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 1LC BK-100bleomisin · intravenöztam yanıt 1 gün (1 hasta)Canine trichoblastoma is a benign tumour derived from the trichoblastic epithelium, commonly affecting the head and neck and, less commonly, the limbs and trunk. Herein, the authors report a…
Gen ET
Impellizeri et al · J Transl Med
2018Hayvan ÇalışmasıHayvan (İn Vivo)Gen Elektrotransferi (Plazmid DNA)–Vet-ePorator™plazmid DNA · intratümöralgenel sağkalım 64.5 hafta (17 hasta)Background: we have recently shown that Tel-eVax, a genetic vaccine targeting dog telomerase (dTERT) and based on Adenovirus (Ad)/DNA Electro-Gene-Transfer (DNA-EGT) technology can induce st…
IRE
Latouche et al · Technol Cancer Res Treat
2018Hayvan ÇalışmasıHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü– / 3VoltMed HFIRE-waveform generator, blunt-tip electrodes––High-frequency irreversible electroporation is a nonthermal method of tissue ablation that uses bursts of 0.5- to 2.0-microsecond bipolar electric pulses to permeabilize cell membranes and i…
ECT
Cunha et al · Cienc. Rural
2017Hayvan ÇalışmasıHayvan (İn Vivo)–––bleomisin · intravenöztam yanıt 14 gün (3 hasta): Extramedullary plasmacytomas (EPs) are responsible for 2.5% of neoplasms in dogs. They are solitary, smooth, elevated, pink or red nodules, of 1 to 2cm in diameter. Cutaneous and oral extr…
Gen ET
Salvadori et al · Radiol Oncol
2017Hayvan ÇalışmasıHayvan (İn Vivo)Gen Elektrotransferi (Plazmid DNA), İnterlökin-12 Aracılı İmmün Uyarım– / 11Cliniporatorsisplatin · intratümöraltam yanıt 7 adet (11 hasta)Background: The study was aimed to characterize tumor response after combined treatment employing electrochemotherapy with IL-12 gene electrotransfer in dogs with spontaneous mast cell tumor…
ECT
Kulbacka et al · SVR
2017Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 1BTX ECM830bleomisin · hem intravenöz hem intratümöraltümör hacmi değişimi 140.11 cm³Oral melanomas commonly occur in elderly dogs resulting in darkly pigmented areas of the mouth, tongue and gums. The main object of this study was a severe melanoma diagnosed in the jaw of a…
ECT
Maglietti et al · Radiol Oncol
2017Hayvan ÇalışmasıHayvan (İn Vivo)Elektrot Geometrisi ve Yerleşimi–BTX ECM830bleomisin · intravenöznesnel yanıt 91% (11 hasta)Background: Nasal cavity tumors are usually diagnosed late, when they already have infiltrated adjacent tissues thus requiring very aggressive treatments with serious side effects. Here we u…
Gen ET
Cemazar et al · Vet Comp Oncol
2016Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)– / 18Cliniporatordiğer · intratümöralnesnel yanıt 83% (18 lezyon)Electrochemotherapy combined with peritumoral interleukin-12 (IL-12) gene electrotransfer was used for treatment of mast cell tumours in 18 client-owned dogs. Local tumour control, recurrenc…
Gen ET
Cicchelero et al · Vet Comp Oncol
2016Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)–Agile Pulse generatorplazmid DNA · intratümöral–Interleukin 12 (IL-12) is a powerful immunostimulatory cytokine with a strong antitumoural activity. In this work, the immunological, anti-angiogenic and clinical effects of three consecutiv…
Gen ET
Maglietti et al · European Journal of Cancer
2016Hayvan ÇalışmasıHayvan (İn Vivo)Apoptoz İndüksiyonu, Gen Elektrotransferi (Plazmid DNA)––plazmid DNA · diğer yollokal kontrol 4 adet (5 hasta)Immune checkpoint inhibitor Programmed Death Ligand 1 (PD-L1) is upregulated in many malignancies which often correlates with unfavorable prognosis. PD-L1 on cancer cells can induce an “exha…
ECT
Lowe et al · Vet Comp Oncol
2016Hayvan ÇalışmasıHayvan (İn Vivo)––Cytopulse PA4000, Cytopulse Oncovet, Cliniporator, Gehl Needle electrodesbleomisin · intravenöztam yanıt 80% (15 hasta)To describe the results of electrochemotherapy (ECT) in dogs with mast cell tumours (MCTs) either as first line therapy or as an adjuvant to surgery. The treatment combines administration of…
Diğer EP
Souza et al · J Vet Pharmacol Ther
2016Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması–BTX ECM830bleomisinhücre canlılığı 12%Electroporation is a method used to deliver poorly permeant chemotherapeutic drugs to tumor cells, potentiating the cytotoxic effects of drugs and overall clinical response. Despite existing…
ECT
Suzuki et al · Artif Organs
2016Hayvan ÇalışmasıHayvan (İn Vivo)Elektrot Geometrisi ve Yerleşimi, Bleomisin Hücre İçi Birikiminin Artması–BTX ECM830bleomisin · topikal–Electrochemotherapy is a new modality of local cancer treatment that increases the delivery of chemotherapy drugs into tumor cells by applying intense electric fields. This novel electrochem…
ECT
Tozon et al · Vet Rec
2016Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması– / 69Jouan GHT 1287, Cliniporatorsisplatin · intratümöraltam yanıt 92.3% (52 lezyon)The aim of our study was to evaluate the efficacy of electrochemotherapy (ECT) with cisplatin as a single or adjuvant treatment for sarcoids in equids. Different treatment options with diffe…
ECT
Tozon et al · J Vis Exp
2016Hayvan ÇalışmasıHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, Bleomisin Hücre İçi Birikiminin Artması––bleomisin · hem intravenöz hem intratümöral–Electrochemotherapy (ECT) is a local approach which is used for treating solid tumors of different histologies. Its mechanism is based on cell membrane permeabilization by means of "electrop…
ECT
Spugnini et al · J Vet Intern Med
2015Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Kas Kasılması ve Anestezi Gereksinimi–Chemipulse IIIbleomisin · intravenöz–Background: Advanced carcinoma of the head represents a substantial health problem in cats for local control and overall survival. Objectives: Evaluate the capability of electrochemotherapy …
IRE
Rossmeisl et al · J Neurosurg
2015Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu7 / 7NanoKnife––Object: Irreversible electroporation (IRE) is a novel nonthermal ablation technique that has been used for the treatment of solid cancers. However, it has not been evaluated for use in brain…
ECT
F.H. Maglietti et al · J. Anal. Oncol.
2014Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Hemostaz ve Kanama Kontrolü– / 1BTX ECM830bleomisin · intravenöztümör hacmi değişimi 83%Background: Electrochemotherapy is a novel tumor treatment routinely used for cutaneous and subcutaneous tumors in human patients in the European Union since 2006. Here we used it to treat a…
Diğer EP
Riccardo et al · Clin Cancer Res
2014Hayvan ÇalışmasıHayvan (İn Vivo)Gen Elektrotransferi (Plazmid DNA)–Cliniporatorplazmid DNA · intratümöral–Purpose: Due to the many similarities with its human counterpart, canine malignant melanoma (cMM) is a valuable model in which to assess the efficacy of novel therapeutic strategies. The mod…
ECT
Tellado et al · Case Reports in Veterinary Medicine
2014Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Kas Kasılması ve Anestezi Gereksinimi– / 1BTX ECM830bleomisin · intravenöztam yanıt 100%A case of a canine oral eosinophilic granuloma in a 14-year-old female crossbred is described. The dog was presented with a history of ptyalism, halitosis, local pain, decreased appetite, an…
ECT
Tozon et al · J Feline Med Surg
2013Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–Cliniporatorbleomisin · intravenöz–The aim of this study was to evaluate the efficacy and safety of electrochemotherapy (ECT) with bleomycin for treatment of squamous cell carcinoma (SCC) in cats. Between March 2008 and Octob…
Belirlenmedi
Gavazza et al · Hum Gene Ther
2013Hayvan ÇalışmasıHayvan (İn Vivo)–––plazmid DNA · intratümöralgenel sağkalım 76.1 hafta (21 hasta)Client-owned pet dogs represent exceptional translational models for advancement of cancer research because they reflect the complex heterogeneity observed in human cancer. We have recently …
ECT
Scacco et al · Journal of Equine Veterinary Science
2013Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması– / 2Chemipulse III, Chemipulse III portable electroporatorsisplatin · intratümöral–A 25-year-old gelding sport horse was referred for the treatment of recurring bilateral anal amelanotic melanoma. On physical examination, the horse presented bilateral poorly delimited peri…
ECT
Spugnini et al · J Vet Intern Med
2011Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu–Chemopulsesisplatin · intratümöralhastalıksız sağkalım 78% (37 hasta)Background: Electrochemotherapy (ECT) couples the administration of anticancer drugs with the delivery of electric pulses that increase the drug uptake through the cell membranes, resulting …
Gen ET
Pavlin · Radiol Oncol
2011Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)– / 11–plazmid DNA · intratümöral–Background: Mast cell tumors (MCT) are the most common malignant cutaneous tumors in dogs with extremely variable biological behaviour. Different treatment approaches can be used in canine c…
ECT
Spugnini et al · Journal of Equine Veterinary Science
2011Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması–Chemipulse III, Chemipulse III portable electroporatorsisplatin · intratümöraltümör hacmi değişimi 50%A 22-year-old Camargue mare was referred for showing signs of discomfort during chewing, building up of food in the mouth, and foul odor from the mouth. On physical examination, the mare pre…
ECT
Tamzali et al · Equine Vet J
2011Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması, Reversible Membran Permeabilizasyonu– / 194BetaTech, PS 15sisplatin · intratümöraltam yanıt 0.979 oran (48 hayvan)Reasons for performing study: Sarcoids are the commonest form of equine skin tumour. Several therapeutic measures have been described but none is considered to be universally effective. Elec…
ECT
Reed et al · Cancer Gene Ther
2010Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, İnterlökin-12 Aracılı İmmün Uyarım–BTX ECM830, hexagonal array of six-needle electrodesbleomisin · intratümöraltam yanıt 3 adet (6 hasta)On the basis of superior outcomes from electrochemogene therapy (ECGT) compared with electrochemotherapy in mice, we determined the efficacy of ECGT applied to spontaneous canine neoplasms. …
ECT
Reed et al · Cancer Gene Ther
2010Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, İnterlökin-12 Aracılı İmmün Uyarım– / 6BTX ECM830bleomisin · intratümöraltam yanıt 3 adet (6 hasta)On the basis of superior outcomes from electrochemogenetherapy (ECGT) compared with electrochemotherapy in mice, we determined the efficacy of ECGT applied to spontaneous canine neoplasms. I…
ECT
Tozon et al · Acta vet. (Beogr.)
2010Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması– / 66Jouan GHT 1287, Cliniporatorsisplatin · intratümöralnesnel yanıt 93.9% (66 lezyon)Perianal tumors are common in older male dogs. The usefulness of electrochemotherapy in veterinary oncology has already been demonstrated by clinical studies on different malignancies in com…
Diğer EP
Chuang et al · Int J Cancer
2009Hayvan ÇalışmasıHayvan (İn Vivo)İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA)–BTX ECM830, Electro Square Porator ECM 830 pulse generatorplazmid DNA · intratümöral–Interleukin-12 (IL-12) is effective in treating many types of rodent tumors, but has been unsuccessful in most human clinical trials, suggesting that animal models of more clinical relevance…
ECT
Kodre et al · In Vivo
2009Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması– / 12IGEA plate electrodessisplatin · intratümöraltam yanıt 62.5% (9 hasta)Unlabelled: The aim of this study was to evaluate the effectiveness of local treatment electrochemotherapy (ECT) with cisplatin and to compare it with effectiveness of surgery for treatment …
ECT
Spugnini et al · Vet J
2009Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması– / 9chemopulsebleomisin · intratümöraltam yanıt 7 adet (9 hasta)Squamous cell carcinomas (SCC) of the skin are commonly described in cats. Reported treatments include surgery, radiation therapy and photodynamic therapy. This preliminary study reports on …
ECT
Spugnini et al · J Exp Clin Cancer Res
2008Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi–Chemopulsebleomisin · intratümöraltam yanıt 3 adet (3 hasta)Sticker's sarcoma (also known as transmissible venereal tumor) is a horizontally transmitted neoplasm of the dog, that is passed with coitus. It is a locally aggressive tumor with a low tend…
ECT
Spugnini et al · In Vivo
2007Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt–Chemopulsebleomisin · intratümöral–Electrochemotherapy (ECT) is a new therapeutical technique that combines the administration of trains of biphasic pulses with the local application of poorly permeant anticancer molecules, t…
ECT
Spugnini et al · J Exp Clin Cancer Res
2007Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi–Chemopulsebleomisin–Perianal tumors (adenoma and carcinoma of the hepatoid glands) are frequently reported in veterinary literature. They are locally aggressive tumors with a low tendency to metastatic spread. …
ECT
Spugnini et al · J Exp Clin Cancer Res
2007Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi–Chemopulsebleomisin · intratümöraltam yanıt 6 adet (6 hasta)Non Hogdkin's lymphoma is the commonest malignant neoplasm in humans and in pets. Treatments include systemic chemotherapy eventually combined with radiation therapy. Radiation therapy is al…
ECT
Spugnini et al · J Transl Med
2007Hayvan ÇalışmasıHayvan (İn Vivo)Apoptoz İndüksiyonu, Nekroz ve Nekroptoz–CHEMOPULSEbleomisin · intratümöral–Electrochemotherapy (ECT) is a novel anticancer therapy that is currently being evaluated in human and pet cancer patients. ECT associates the administration of an anti-tumor agent to the de…
ECT
Spugnini et al · Anticancer Res
2006Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Darbe Parametrelerinin Optimizasyonu– / 28Chemopulse, Chemopulse clinical electroporation equipmentbleomisin · intratümöralgenel sağkalım 85% (28 hasta)Background: Electrochemotherapy (ECT) is a novel anticancer therapy that combines the delivery of trains of appropriate waveforms with the local administration of chemotherapy agents. The pu…
ECT
Tozon et al · Anticancer Res
2005Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması– / 26Jouan GHT 1287sisplatin · intratümöralnesnel yanıt 82% (26 lezyon)Background: Electrochemotherapy is an antitumor therapy that utilizes locally-delivered, short intense direct current electric pulse to the tumor nodule plus chemotherapy. The aim of the pre…
ECT
Rols et al · Bioelectrochemistry
2002Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması– / 10Jouan Electropulsator, PS 15sisplatin · intratümöraltam yanıt 100% (10 lezyon)Sarcoids are skin spontaneous tumours detected in horses. It can be cured by chemotherapy by using cisplatin. A multisequence treatment must be performed. Problems are present due to the poo…
ECT
Tozon et al · Anticancer Res
2001Hayvan ÇalışmasıHayvan (İn Vivo)Sisplatin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu––––The aim of this study was to introduce electrochemotherapy with cisplatin into veterinary medicine, where there is a need for inexpensive and effective treatment of cutaneous and subcutaneou…
ECT
Mir et al · Br J Cancer
1997Hayvan ÇalışmasıHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması–PS 15, CELTEM MKO generatorbleomisin · intravenözgenel sağkalım 6.1 ay (12 hasta)Electrochemotherapy combines bleomycin and local electric pulses that allow cell permeabilization and free access of bleomycin to its intracellular target. We report the first veterinarian c…
ECT
Suzuki et al · Artif Organs
2017İn Siliko / ModellemeHesaplamalı ModelElektrik Alan Dağılımı ve Modellemesi, Reversible Membran Permeabilizasyonu– / 1BTX ECM830bleomisin · intravenöztümör hacmi değişimi 0 cm³ (1 hasta)Electrochemotherapy (EQT) is a local cancer treatment well established to cutaneous and subcutaneous tumors. Electric fields are applied to biological tissue in order to improve membrane per…
ECT
Suzuki et al · Artif Organs
2014İn Siliko / ModellemeHesaplamalı ModelElektrik Alan Dağılımı ve Modellemesi, Elektrot Geometrisi ve Yerleşimi–BTX ECM830bleomisin · intravenöz–Electrochemotherapy is a combination of high electric field and anticancer drugs. The treatment basis is electroporation or electropermeabilization of the cell membrane. Electroporation is a…
ECT
Rangel · Artif Organs
2018Editöryal / MektupHayvan (İn Vivo)–––bleomisintam yanıt 1 adet (1 hasta), First of all, thank you for your inquiries and your careful reading of our published article (1). The following is a response to valuable questions in our work: 1. Nasal carcinoma (TVT)—Ye…
ECT
Osorio‐Morales et al · Artif Organs
2017Editöryal / MektupHayvan (İn Vivo)–––––, We refer you to the study entitled “Novel Application for Electrochemotherapy: Immersion of Nasal Cavity in Dog” in which, Suzuki et al. (1) report the successful chemotherapeutic treatmen…
ECT
Salmoral et al · JFMS Open Rep
2025Düzeltme / ErratumHayvan (İn Vivo)–––sisplatin · intratümöral–[This corrects the article DOI: 10.1177/20551169231213499.].
ECT
Dos Anjos et al · Sci Rep
2021Düzeltme / ErratumHayvan (İn Vivo)Bleomisin Hücre İçi Birikiminin Artması––bleomisin–An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Sınırlılıklar

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Korpusun nasıl derlendiği, kademe eşikleri, klinik yayın tanımı ve yöntemlerin birbirinden ayrı sayılması: Literatür Haritası.