Grup: Özel Endikasyonlar
Veteriner Onkoloji
Elektrokemoterapi veteriner onkolojide, sahipli hayvanlarda kendiliğinden gelişen tümörler üzerinde uzun süredir klinik olarak çalışılmaktadır. Bu kayıtlar insan endikasyonlarının kanıtı değildir; ancak kendiliğinden tümör taşıyan büyük hayvanlarda doz, elektrot ve yanıt verisi ürettikleri için translasyonel bir köprü oluşturur.
Klinik yayın: randomize, prospektif ve retrospektif çalışma, vaka serisi ve vaka raporu. Preklinik yayın: hayvan, in vitro, modelleme ve deneysel biyofizik çalışmaları.
Yayınların Bildirdiği Klinik ve Teknik Veriler
Bu alandaki 158 yayının 157 tanesinde tam metinde bildirilen alanların toplamı. Sayılar toplanır, yorumlanmaz.
Toplamlar benzersiz hasta sayısı değildir: aynı kohort birden fazla yayında raporlanmış olabilir.
Yönteme Göre Literatür Durumu
Klinik yöntem başına yayın sayısı, klinik ve preklinik dağılım, literatür hacmi ve yayın aralığı. Sayfa girişindeki rozet yalnızca ECT kaydını özetler; yöntem ayrımının tamamı buradadır.
Elektrokemoterapi (ECT)
Keşifsel / düşük hacimli literatüreşik 2/122 kayıt
Bu sayının klinik ve preklinik dağılımı: klinik 0, preklinik 1.
1997–2026
İrreversible elektroporasyon (IRE)
Keşifsel / düşük hacimli literatüreşik 0/4 kayıt
Bu yöntemin hiçbir kaydı hacim etiketine girmemiştir.
2015–2024
Kalsiyum elektroporasyonu
Keşifsel / düşük hacimli literatüreşik 0/4 kayıt
Bu yöntemin hiçbir kaydı hacim etiketine girmemiştir.
2019–2026
Gen elektrotransferi
Keşifsel / düşük hacimli literatüreşik 3/18 kayıt
Bu sayının klinik ve preklinik dağılımı: klinik 0, preklinik 2.
2011–2026
Diğer elektroporasyon uygulamaları
Bu küme tek bir klinik yöntemi adlandırmaz; literatür hacmi atanmaz.
2009–2024
Yöntemi belirlenmemiş kayıtlar
Bu küme tek bir klinik yöntemi adlandırmaz; literatür hacmi atanmaz.
2013–2025
Özetlerde Anılan Mekanizmalar
Rakam, mekanizma adının geçtiği özet sayısıdır. Bir mekanizmanın anılması, o çalışmada gösterildiği anlamına gelmez.
Çalışma Tipi Dağılımı
Yüzde, alanın tamamındaki payı verir.
| Çalışma tipi | Yayın | Bu alandaki payı |
|---|---|---|
| Vaka Raporu | 27 | %17 |
| Kılavuz / Uzlaşı | 1 | <%1 |
| Derleme | 19 | %12 |
| Hayvan Çalışması | 105 | %66 |
| İn Siliko / Modelleme | 2 | %1 |
| Editöryal / Mektup | 2 | %1 |
| Düzeltme / Erratum | 2 | %1 |
Yayın Tablosu
158 yayın kaydı, çalışma tasarımına göre sıralanmıştır. Başlığa tıklayarak künye, mekanizma ve tam özet çekmecesini açabilirsiniz.
Sınıflandırmalar otomatik üretilir ve tekil kayıtlarda hata içerebilir. Metodoloji
| Rejim | Yayın | Yıl | Çalışma tipi | Model | Mekanizma | Hasta / lezyon | Cihaz | Ajan ve yol | Bildirilen sonuç | Özet |
|---|---|---|---|---|---|---|---|---|---|---|
| ECT | Maggi et al · Front Vet Sci | 2026 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | – / 2 | Cliniporator VITAE | bleomisin · intravenöz | tümör hacmi değişimi 81% (1 lezyon) | Electrochemotherapy is a local anticancer treatment used for selected cutaneous tumors, but its application in veterinary medicine for nasal neoplasms is only rarely reported. Two dogs with … |
| ECT | Peña et al · Vet Ophthalmol | 2026 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Reversible Membran Permeabilizasyonu | – / 2 | Cavity electrode (Leroy Biotech) | bleomisin · hem intravenöz hem intratümöral | tam yanıt 100% (2 hasta) | Background: Squamous cell carcinoma (SCC) is one of the most common malignant eyelid tumors in cats, especially in white-haired individuals chronically exposed to sunlight. Electrochemothera… |
| Gen ET | Lampreht Tratar et al · Front Vet Sci | 2026 | Vaka Raporu | Hayvan (İn Vivo) | Elektrot Geometrisi ve Yerleşimi, İnterlökin-12 Aracılı İmmün Uyarım | – / 1 | Cliniporator | sisplatin · intratümöral | tam yanıt 180 gün (1 lezyon) | Electrochemotherapy (ECT) combined with gene electrotransfer of interleukin-12 (IL-12 GET) has shown promising results in the treatment of canine mast cell tumors (MCTs). However, when tumor… |
| ECT | Akiyoshi et al · Front Vet Sci | 2026 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Elektrik Alan Dağılımı ve Modellemesi | – / 1 | ELECTROVET EZ | bleomisin · intravenöz | genel sağkalım 120 gün (1 hasta) | A 14-year-old spayed female Persian cat with lingual feline oral squamous cell carcinoma (FOSCC) was treated with bleomycin-based electrochemotherapy (ECT), resulting in sustained preservati… |
| ECT | Ruanova et al · Open Vet J | 2025 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | Onkodisruptor | bleomisin · intravenöz | tam yanıt 4 adet (4 hasta) | Background: Cutaneous mast cell tumor (MCT) is one of the most common skin neoplasms in cats and typically exhibits clinically benign behavior. Multiple MCTs, recurrent tumors, or infiltrate… |
| ECT | Andrade et al · Braz J Vet Med | 2024 | Vaka Raporu | Hayvan (İn Vivo) | Nekroz ve Nekroptoz | – / 1 | ePORE | bleomisin · intravenöz | – | An 8-year-old male rabbit ( Oryctolagus cuniculus ) presented with a subcutaneous mass in the proximal region of the fourth and accessory digit measuring 5.5 x 3.5 x 5.2cm. The mass was non-… |
| ECT | Larsen et al · Vet Ophthalmol | 2024 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | – / 2 | CLINIVET VEP02 | bleomisin · intratümöral | tam yanıt 100% (2 lezyon) | Objective: To describe the procedure and outcome of electrochemotherapy (ECT) with bleomycin as a first-line treatment for bilateral ocular surface squamous neoplasia (OSSN) in the eye of a … |
| ECT | Pimentel et al · Top Companion Anim Med | 2024 | Vaka Raporu | Hayvan (İn Vivo) | – | – | VetCP125 | bleomisin · intravenöz | genel sağkalım 707 gün | Apocrine sweat gland adenocarcinoma (ASGAC) is a rare skin carcinoma in cats. In some cases, this tumor occurs in anatomical sites of challenging wide surgical resection, which increases the… |
| ECT | Salmoral et al · JFMS Open Rep | 2024 | Vaka Raporu | Hayvan (İn Vivo) | Kalsiyum Elektroporasyonu ve ATP Tükenmesi | – | Onkodisruptor | bleomisin · intravenöz | tam yanıt 3 adet (3 hasta) | Case series summary: Malignant basal cell tumours may be seen on or near the nasal planum in cats, and include basal cell carcinomas, which are common, and basosquamous carcinomas, which are… |
| ECT | Sena et al · Front Vet Sci | 2024 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 5 | VETCP 125, ePORE | bleomisin · intravenöz | tam yanıt 1 adet (1 hasta) | Feline histiocytic diseases are uncommon and rarely reported. Feline progressive histiocytosis (FPH) is the most common histiocytic disease in cats, predominantly affecting middle-aged anima… |
| ECT | Dos Santos da Luz et al · Vet Res Forum | 2023 | Vaka Raporu | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu | – / 1 | VetCP 125 | bleomisin · intravenöz | – | Melanocytoma and malignant melanoma are the most typical eye tumors in dogs and cats. Due to the presence of melanin, the general appearance is often highly pigmented in a nodular formation … |
| ECT | Little et al · JFMS Open Rep | 2022 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 1 | Onkodisruptor | bleomisin · intravenöz | – | Case summary: A 4-year-old domestic shorthair cat presented to North Downs Specialist Referrals for treatment of a 7 mm melanoma of the nasal planum. Two treatments of electrochemotherapy us… |
| ECT | Dos Anjos et al · Vet Res Forum | 2020 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | Onkodisruptor | bleomisin · intravenöz | – | Electroporation is a technique that increases the uptake of chemotherapeutic drugs by tumors. Electrochemotherapy (ECT) has been successfully used to treat solid tumors. Recently, novel appl… |
| ECT | Martins Taques et al · Artif Organs | 2020 | Vaka Raporu | Hayvan (İn Vivo) | Elektrot Geometrisi ve Yerleşimi, Elektrik Alan Dağılımı ve Modellemesi | – / 1 | VetCp 125 | bleomisin · intravenöz | – | Osteosarcoma is a bone cancer considered rare to humans, but common in dogs. Dogs and humans share genetic homology and environmental risk factors. Improving the treatment of osteosarcoma in… |
| ECT | Santos dos Anjos et al · Top Companion Anim Med | 2020 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | – | – · hem intravenöz hem intratümöral | – | Plasma cell tumors can occur as solitary collections referred as extramedullary plasmocytoma (EMP). The present report describes four cases of EMP treated with a local nonthermal ablative ap… |
| ECT | Tunikowska et al · Animals (Basel) | 2020 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Nekroz ve Nekroptoz | – | PPG-20 generator | bleomisin · intratümöral | tam yanıt 1 adet (1 hayvan) | Background: The aim of this study was to present the first domestic animal trial of nanosecond electroporation with chemotherapy and CO 2 laser surgery. Methods: sixteen-year-old domestic ca… |
| ECT | Racnik et al · Journal of Exotic Pet Medicine | 2019 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – / 1 | Cliniporator | bleomisin · intratümöral | tam yanıt 100% (1 lezyon) | A 12-year-old female cockatiel (Nymphicus hollandicus) was presented with a squamous cell carcinoma involving the uropygial gland. Electrochemotherapy (ECT) as a minimally invasive treatment… |
| ECT | Torrigiani et al · Vet Comp Oncol | 2019 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 54 | Cytopulse PA4000, Cytopulse Oncovet | bleomisin · intravenöz | genel sağkalım 75% (4 lezyon) | Canine soft tissue sarcomas (STSs) are locally invasive mesenchymal neoplasms. Electrochemotherapy (ECT) is an antitumour local ablative treatment that uses electric pulses to enhance the in… |
| ECT | Spugnini et al · Open Vet J | 2017 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | – / 1 | Onkodisruptor | bleomisin · intravenöz | tümör hacmi değişimi 50% (1 hasta) | A twelve-year-old male castrated domestic shorthair cat was presented for rapidly progressing respiratory distress. The cat was depressed, tachypneic and moderately responsive. Ultrasonograp… |
| ECT | Spugnini et al · Open Vet J | 2016 | Vaka Raporu | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 1 | Onkodisruptor | sisplatin · intratümöral | hastalıksız sağkalım 12 ay (1 hasta) | An eleven-year-old stallion was referred for adjuvant treatment of an incompletely excised, recurring penile fibrosarcoma. The horse was bright, alert and responsive with a 15 x 12 cm ulcera… |
| ECT | Spugnini et al · Can Vet J | 2013 | Vaka Raporu | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması, Bleomisin Hücre İçi Birikiminin Artması | – / 1 | Chemipulse III | diğer · hem intravenöz hem intratümöral | tam yanıt 1 ay (1 hasta) | This paper reports the clinical findings, histopathology, and clinical outcome of a rare case of aponeurotic fibromatosis in a dog. The dog was treated with 4 courses of electrochemotherapy … |
| ECT | Spugnini et al · J Small Anim Pract | 2010 | Vaka Raporu | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – | Chemopulse electroporator, Chemopulse | sisplatin · intratümöral | tam yanıt 100% (1 hayvan) | A 13-year-old male neutered cat was presented for the sudden growth of two nodular lesions close to the upper eyelid of both eyes. Fine-needle aspiration cytology was suggestive of mesenchym… |
| ECT | Spugnini et al · In Vivo | 2008 | Vaka Raporu | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 1 | – | sisplatin · intratümöral | tam yanıt 18 ay (1 hasta) | Canine anal sac gland carcinoma (ASGC) is a frequently described neoplasm that is highly aggressive and can frequently lead to metastatic spread. In this paper, we describe the successful tr… |
| ECT | Spugnini et al · In Vivo | 2008 | Vaka Raporu | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – | – | sisplatin | – | Electrochemotherapy is gaining popularity for the treatment of malignancies of companion animals due to its efficacy and low cost. In this paper, we describe the successful treatment of a re… |
| ECT | Spugnini et al · Vet J | 2008 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – / 1 | modified calliper electrodes | bleomisin · intratümöral | tam yanıt 1 adet (1 hasta) | An 8-year-old male castrated cat was referred for sudden onset of lameness. Physical examination revealed a 1x2x1cm mass originating from a footpad of the right hind leg. A diagnosis of gang… |
| ECT | Spugnini et al · Vet Rec | 2008 | Vaka Raporu | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 1 | – | bleomisin · intratümöral | tam yanıt 1 gün (1 lezyon) | Short Communications Surgery and electrochemotherapy of a high-grade soft tissue sarcoma in a dog E. P. Spugnini, B. Vincenzi, G. Betti, F. Cordahi, I. Dotsinsky, N. Mudrov, G. Citro, A. Bal… |
| ECT | Spugnini et al · In Vivo | 2007 | Vaka Raporu | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt | – / 1 | – | sisplatin · intratümöral | tümör hacmi değişimi 50% (1 lezyon) | Canine anal melanoma is an aggressive neoplasm that rapidly leads to constipation in dogs, thus mimicking the behavior of their human counterpart. In this paper, the successful local palliat… |
| ECT | Tellado et al · Front Vet Sci | 2022 | Kılavuz / Uzlaşı | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | – | bleomisin · intravenöz | – | Electrochemotherapy (ECT) consists in the application of electric pulses to increase chemotherapeutic drug intake (bleomycin, cisplatin, or calcium) into the tumor cells. It has become a ver… |
| ECT | Ertürk ve Özsoy · – | 2026 | Derleme | Hayvan (İn Vivo) | – | – | – | bleomisin · intratümöral | tam yanıt 100% (1 hasta) | ( ) * Corresponding author: Esma Hande Ertürk Phone: +90 535 015 23 61 E-mail: esmahande.sevis@ogr.iuc.edu.tr How to cite this article? Ertürk EH, Özsoy S: Electrochemotherapy as an Emerging… |
| ECT | Ramos et al · Vet Comp Oncol | 2024 | Derleme | Hayvan (İn Vivo) | – | – | – | – · hem intravenöz hem intratümöral | – | Electrochemotherapy (ECT) is a treatment modality that combines the electroporation of cell membranes with chemotherapy to facilitate the transport of non-permeant molecules into cells. Seve… |
| Diğer EP | Spugnini et al · Cancers (Basel) | 2024 | Derleme | Literatür Analizi | Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü | – | – | – | – | Electroporation (EP) is a broadly accepted procedure that, through the application of electric pulses with appropriate amplitudes and waveforms, promotes the delivery of anticancer molecules… |
| Diğer EP | Pazzi et al · Vet Sci | 2022 | Derleme | Literatür Analizi | – | – | – | bleomisin · intravenöz | genel sağkalım 225 gün (67 hasta) | Critical appraisal of the available literature for the treatment of canine oral malignant melanoma (OMM) is lacking. This critical review aimed to evaluate the current literature and provide… |
| Gen ET | Maglietti et al · Vaccines (Basel) | 2020 | Derleme | Literatür Analizi | Gen Elektrotransferi (Plazmid DNA), Reversible Membran Permeabilizasyonu | – | – | bleomisin | – | Electroporation is a technology that increases cell membrane permeability by the application of electric pulses. Electrochemotherapy (ECT), the best-known application of electroporation, is … |
| Diğer EP | Nemec et al · Front Vet Sci | 2020 | Derleme | Literatür Analizi | Gen Elektrotransferi (Plazmid DNA) | – | – | bleomisin · intravenöz | – | Electroporation is a method of inducing an increase in permeability of the cell membrane through the application of an electric field and can be used as a delivery method for introducing mol… |
| ECT | Rangel et al · Austral j. vet. sci. | 2019 | Derleme | Hayvan (İn Vivo) | Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | – | bleomisin | – | Electrochemotherapy (ECT) is a technique that combines chemotherapy with local application of specific electric pulses with the aim of increasing the permeability of the plasma membrane in a… |
| ECT | Tunikowska J, Kulbacka J, Michel O, Kiełbowicz Z · Weterynaria w Praktyce | 2018 | Derleme | belirsiz | Antivasküler Etki ve Damar Yıkımı | – | – | bleomisin · hem intravenöz hem intratümöral | – | The modern treatment of veterinary oncologic patients often relies on polytherapy which combines standard surgical excision with additional treatment modality. Electrochemotherapy (ECT) is t… |
| Belirlenmedi | Cramp P · – | 2017 | Derleme | Hayvan (İn Vivo) | – | – | – | sisplatin | – | Melanomas are a well-known problem of the grey horse population, with grey horses having an 80% probability of developing melanomas in their life [1]. There seems to be no sex predilection, … |
| ECT | Goanta et al · AGROLIFE | 2017 | Derleme | Hayvan (İn Vivo) | Kas Kasılması ve Anestezi Gereksinimi, Bleomisin Hücre İçi Birikiminin Artması | – | – | bleomisin · hem intravenöz hem intratümöral | – | Electrochemotherapy (ECT) is a recent anticancer treatment used for solid tumours in which square wave electric pulses are combined with a chemotherapeutic drug administered either intraveno… |
| Gen ET | Pavlin et al · Handbook of Electroporation | 2017 | Derleme | Literatür Analizi | Gen Elektrotransferi (Plazmid DNA), İnterlökin-12 Aracılı İmmün Uyarım | – | – | bleomisin · intratümöral | tam yanıt 100% | Veterinary medicine has become an important translational bridge from in vitro and preclinical studies to human medicine, offering invaluable model for research in naturally occurring diseas… |
| ECT | Tozon et al · Handbook of Electroporation | 2017 | Derleme | Literatür Analizi | Sisplatin Hücre İçi Birikiminin Artması, Bleomisin Hücre İçi Birikiminin Artması | – | – | bleomisin · intravenöz | nesnel yanıt 79% | In veterinary oncology, the clinical studies on electrochemotherapy are not numerous. Electrochemotherapy in veterinary oncology is used with two chemotherapeutic drugs, cisplatin and bleomy… |
| Diğer EP | Impellizeri et al · Vet J | 2016 | Derleme | Hayvan (İn Vivo) | – | – | – | bleomisin · intravenöz | – | Cancer treatments in veterinary medicine continue to evolve beyond the established standard therapies of surgery, chemotherapy and radiation therapy. New technologies in cancer therapy inclu… |
| ECT | Spugnini et al · J Cell Physiol | 2016 | Derleme | Hayvan (İn Vivo) | – | – | – | – | – | Electrochemotherapy (ECT) is a medical strategy that allows an increased efficacy of chemotherapy agents after the application of permeabilizing electric pulses having appropriate characteri… |
| ECT | Spugnini et al · Curr Cancer Drug Targets | 2015 | Derleme | Hayvan (İn Vivo) | – | – | – | bleomisin · intratümöral | – | Tumor microenvironment is one of the major obstacles to the efficacy of chemotherapy in cancer patients. The abnormal blood flow within the tumor results in uneven drug distribution. Electro… |
| Gen ET | Pavlin · J Transl Med | 2012 | Derleme | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – | – | plazmid DNA · intratümöral | – | The use of large animals as an experimental model for novel treatment techniques has many advantages over the use of laboratory animals, so veterinary medicine is becoming an increasingly im… |
| ECT | Spugnini et al · Future Oncol | 2012 | Derleme | Hayvan (İn Vivo) | – | – | – | bleomisin · hem intravenöz hem intratümöral | – | Electrochemotherapy is a tumor treatment that adapts the systemic or local delivery of anticancer drugs by the application of permeabilizing electric pulses with appropriate amplitude and wa… |
| ECT | Spugnini et al · J Exp Clin Cancer Res | 2009 | Derleme | Hayvan (İn Vivo) | – | – | – | bleomisin | – | The treatment of soft tissue tumors needs the coordinated adoption of surgery with radiation therapy and eventually, chemotherapy. The radiation therapy (delivered with a linear accelerator)… |
| ECT | Cemazar et al · J Vet Intern Med | 2008 | Derleme | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, Bleomisin Hücre İçi Birikiminin Artması | – | – | diğer · hem intravenöz hem intratümöral | – | Electropermeabilization is a method that uses electric field pulses to induce an electrically mediated reorganization of the plasma membrane of cells. Electrochemotherapy combines local or s… |
| ECT | Tozon Mask et al · BMC Vet Res | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – / 138 | Cliniporator | bleomisin · intravenöz | tam yanıt 74% (110 lezyon) | Electrochemotherapy (ECT) is a local ablative treatment and in veterinary oncology, evidence supporting ECT efficacy is mainly derived from case reports and small case series, underscoring t… |
| ECT | Franchini et al · – | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, Ekstraselüler Matriks ve Doku İskeletinin Korunması | – | Onkodisruptor | bleomisin · intravenöz | genel sağkalım 1012 gün (39 hasta) | Tumors are complex microenvironments in which uncontrolled cell proliferation alters biochemical pathways as well as the physical and electrical properties of tissues. Electrochemotherapy (E… |
| ECT | Franchini et al · Sci Rep | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, Ekstraselüler Matriks ve Doku İskeletinin Korunması | – / 39 | Onkodisruptor | bleomisin · intravenöz | genel sağkalım 1012 gün (39 hasta) | Tumors are complex microenvironments in which uncontrolled cell proliferation alters biochemical pathways as well as the physical and electrical properties of tissues. Electrochemotherapy (E… |
| ECT | Franchini et al · Vet Comp Oncol | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Nekroz ve Nekroptoz | – | Onkodisruptor | bleomisin · intravenöz | genel sağkalım 640 gün (18 hasta) | Electrochemotherapy is increasingly used as a locoregional treatment for feline squamous cell carcinoma, but its role in advanced nasal planum disease remains poorly defined. This retrospect… |
| ECT | Frigerio et al · Case Rep Vet Med | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – / 1 | ePORE | bleomisin · intravenöz | lokal nüks 0 adet (1 hasta) | Squamous cell carcinoma (SCC) is a malignant epithelial neoplasm commonly affecting the skin and oral cavity of dogs, whereas laryngeal involvement is considered rare. Neoplasms arising in t… |
| ECT | Holanda et al · Vet J | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Nekroz ve Nekroptoz | 35 | – | – | – | Electrochemotherapy (ECT) has emerged as a valuable therapeutic option for feline cutaneous squamous cell carcinoma (SCC). However, the influence of clinicopathological variables on treatmen… |
| Kalsiyum EP | Holst et al · J Am Vet Med Assoc | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Kas Kasılması ve Anestezi Gereksinimi | – / 4 | Cliniporator, linear array probe N-20-4B | kalsiyum klorür · intratümöral | – | Objective: To evaluate the clinical outcome of calcium electroporation in treating canine superficial solid tumors using 1 or 2 treatment sessions and to assess the associated adverse events… |
| ECT | D LESCAI, B BAROIU, A COTIȚOSU, A CRISTEA · Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 1 | Leroy Biotech veterinary electroporation device | bleomisin · hem intravenöz hem intratümöral | tam yanıt 1 adet (1 lezyon) | Mast cell tumors (MCT) in anatomically complex periocular regions of cats often preclude curative surgery. Electrochemotherapy (ECT) offers local control while preserving function. A 17-year… |
| Gen ET | Lisjak et al · Vet Sci | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – | – | bleomisin · intravenöz | tam yanıt 16 adet (24 hasta) | Cancer is a major health concern, with its incidence rate continuing to increase. There is growing interest in the microbiota and its role in carcinogenesis, as it significantly influences p… |
| ECT | Martins et al · Braz J Vet Med | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 1 | Onkodisruptor | bleomisin · intravenöz | tam yanıt 1 adet (1 hasta) | Multilobular Bone Tumor (MBT) is a rare, slow-growing, and locally invasive neoplasm in middle-aged to older dogs, occurring predominantly in flat bones of the skull, pelvis, or ribs. This w… |
| ECT | Milevoj et al · Vet Q | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | Cliniporator | bleomisin · intravenöz | tam yanıt 6 adet (14 lezyon) | Bleomycin (BLM) is a cytotoxic antibiotic used in veterinary oncology, primarily in electrochemotherapy (ECT), a local ablative therapy where electric pulses increase drug uptake in tumours.… |
| ECT | Ojeda et al · J Vet Intern Med | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | Cellporator VetCP 125 | bleomisin · intravenöz | – | Background Mast cell tumors (MCTs) in dogs pose therapeutic challenges that vary with histopathological grade. Hypothesis/objectives Electrochemotherapy (ECT) alone would result in a clinica… |
| ECT | Regadas et al · Top Companion Anim Med | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | BK100 | bleomisin · intravenöz | – | In cats, the high incidence of malignant mammary neoplasms with elevated rates of metastasis and recurrence underscores the need for more effective therapies to prevent disease progression. … |
| ECT | Silva et al · Arq. Bras. Med. Vet. Zootec. | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | ELECTROvet EZ® | bleomisin · intravenöz | lokal nüks 35% (20 hasta) | Feline application sarcoma (FAS) is a mesenchymal malignancy associated with chronic inflammation caused by subcutaneous or intramuscular applications. Surgical resection is the most recomme… |
| ECT | Sofia et al · Vet Comp Oncol | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | Onkodisruptor | bleomisin · intravenöz | lokal nüks 68.2% (22 hasta) | The predominant challenge in canine soft tissue sarcomas (STSs) is achieving local tumour control, for which surgical excision remains the standard treatment. When complete margins are not a… |
| ECT | Spadari et al · Vet Sci | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 23 | ELECTRO vet S13, CLINIVET | sisplatin · intratümöral | lokal kontrol 69.6% (23 lezyon) | Despite the wide range of therapeutic options currently available for equine sarcoids, recurrence of these lesions remains a major clinical challenge. Consequently, the identification of eff… |
| ECT | Ciccarelli et al · Sci Rep | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | Nekroz ve Nekroptoz | 21 | Onkodisruptor | bleomisin · intravenöz | – | Electrochemotherapy (ECT) presents an effective alternative for local tumor management, particularly valuable when surgery is not feasible. The side effects are generally mild, including loc… |
| ECT | Amato et al · Open Vet J | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | Sistemik / Abskopal İmmün Yanıt | – | Onkodisruptor | bleomisin · intravenöz | genel sağkalım 70 gün (9 hasta) | Background: Canine prostatic carcinoma (PC) is an uncommon neoplasia characterized by aggressive biological behavior. Treatment options include surgery (partial or total prostatectomy), radi… |
| Gen ET | Camerino et al · Vet Q | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | – | Cliniporator | plazmid DNA · intratümöral | genel sağkalım 37.7 ay (80 hasta) | Canine oral malignant melanoma (OMM) is an aggressive, spontaneously occurring tumor carrying a poor to guarded prognosis and relatively limited therapeutic strategies. In this landscape, ch… |
| ECT | Costa et al · Cad. Pedagógico | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt | – / 2 | – | bleomisin · intravenöz | – | Canine cutaneous mast cell tumors represent a significant clinical challenge due to the wide variability in biological behavior and the risk of recurrence or metastasis, requiring individual… |
| ECT | Foo et al · J Feline Med Surg | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | Electrovet S13 | bleomisin · intravenöz | tam yanıt 15 adet (23 hasta) | ObjectivesFeline cutaneous squamous cell carcinoma (cSCC) is a malignant tumour arising from squamous epithelium and accounts for 15% of all skin tumours, commonly involving the nasal planum… |
| ECT | Machado et al · Arq. Bras. Med. Vet. Zootec. | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt | – / 1 | – | bleomisin · intravenöz | tam yanıt 3 adet (4 hasta) | Squamous cell carcinoma is a common neoplasm in felines that mainly affects the face, an area that is difficult to treat. Due to its high frequency, it is a challenge in the Oncology Clinic.… |
| ECT | Peña et al · Vet Record Case Reports | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 1 | Electrovet EZ V3.0 | bleomisin · intravenöz | tam yanıt 1 adet (1 hasta) | In recent years, electrochemotherapy has gained relevance in veterinary oncology for the treatment of locally invasive superficial tumours in dogs, such as mast cell tumours, perianal neopla… |
| Belirlenmedi | Rodrigues Soares et al · RVZ | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – / 1 | VetCP | bleomisin · intravenöz | – | O neurofibrossarcoma é descrito como um sarcoma de tecidos moles, caracterizado por um tumor maligno originado das bainhas de nervos periféricos. Atendeu-se no Hospital Veterinário da Univer… |
| Gen ET | Vilfan et al · Animals (Basel) | 2024 | Hayvan Çalışması | Hayvan (İn Vivo) | Nekroz ve Nekroptoz, İnterlökin-12 Aracılı İmmün Uyarım | 48 / 86 | Cliniporator | sisplatin | – | Electrochemotherapy (ECT) in combination with the gene electrotransfer of interleukin 12 (IL-12 GET) has been successfully used in veterinary medicine for the treatment of mast cell tumours … |
| ECT | Diop et al · Vet Comp Oncol | 2024 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | ELECTROvetEZ | diğer · hem intravenöz hem intratümöral | genel sağkalım 669 gün (44 hasta) | Electrochemotherapy (ECT) with intravenous (IV) and/or intratumoral (IT) bleomycin has shown considerable efficacy in the treatment of non-resectable feline cutaneous squamous cell carcinoma… |
| ECT | Ferrer-Jorda et al · J Feline Med Surg | 2024 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | Onkodisruptor | bleomisin · intravenöz | tam yanıt 19 adet (21 hasta) | Objectives: Squamous cell carcinoma (SCC) is the most common tumour in the nasal planum of cats. Surgery has traditionally been the treatment of choice but might not be feasible in locally a… |
| ECT | dos Santos et al · Front Vet Sci | 2024 | Hayvan Çalışması | Hayvan (İn Vivo) | Sistemik / Abskopal İmmün Yanıt | – / 30 | VETCP 125 | bleomisin · intravenöz | – | Introduction: Squamous cell carcinoma (SCC) is a malignant neoplasm that accounts for approximately 15-25% and 70-80% of all feline cutaneous and oral tumors, respectively. Similar to that i… |
| IRE | Hay · Biomedicines | 2024 | Hayvan Çalışması | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü | – / 7 | custom built H-FIRE generator, AngioDynamics bipolar electrodes | – | progresyonsuz sağkalım 100% (5 hasta) | In this study, the feasibility of treating canine primary lung tumors with high-frequency irreversible electroporation (H-FIRE) was investigated as a novel lung cancer treatment option. H-FI… |
| IRE | Fesmire · Front Vet Sci | 2024 | Hayvan Çalışması | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü | – / 45 | – | – | tam yanıt 8 adet (10 lezyon) | Introduction: Integrated time nanosecond pulse irreversible electroporation (INSPIRE) is a novel tumor ablation modality that employs high voltage, alternating polarity waveforms to induce c… |
| ECT | Rangel et al · – | 2023 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 21 | VETCP 125 | bleomisin · intravenöz | nesnel yanıt 86% (21 hasta) | Local treatment of canine urothelial carcinoma (UC) of the bladder is a challenge. More than 90% of cases arise as muscle-invasive tumors, with more than 50% developing on bladder sites with… |
| ECT | Freitas et al · RSD | 2023 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – / 1 | – | diğer · intravenöz | lokal nüks 0 adet (1 hasta) | Squamous cell carcinoma (SCC) is a malignant epithelial neoplasm derived from keratinocytes, commonly preceded by actinic (solar) keratosis, with unclear etiology but associated with host an… |
| ECT | Gokulakrishnan et al · IJAR | 2023 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – / 12 | ELECTRO vet S13 | diğer · intratümöral | tam yanıt 6 adet (6 hasta) | Background: Mammary neoplasms are the most common tumours in the bitch. Even though surgery remained the treatment of choice for mammary gland tumours except those with inflammatory carcinom… |
| Gen ET | Lampreht Tratar et al · Int Immunopharmacol | 2023 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – | – | sisplatin · intratümöral | nesnel yanıt 67% (27 lezyon) | The combined treatment of electrochemotherapy (ECT) and interleukin-12 (IL-12) gene electrotransfer (GET) has already been used in clinical studies in dogs to treat various histological type… |
| ECT | Ribeiro et al · Pesq. Vet. Bras. | 2023 | Hayvan Çalışması | Hayvan (İn Vivo) | Apoptoz İndüksiyonu | – / 18 | LC BK100, LC BK100 electroporator | bleomisin · intravenöz | tam yanıt 8 adet (13 hasta) | : Determining cell proliferation rates and tumor apoptosis through immunohistochemistry allows the evaluation of the biological behavior of the tumor, optimizing the patient’s clinical cours… |
| ECT | de Castro Cunha et al · Vet Comp Oncol | 2023 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | VetCP 125 | bleomisin · intravenöz | nesnel yanıt 90.9% (33 hasta) | Squamous cell carcinoma (SCC) is an important malignancy in dogs, due to its incidence and clinical presentation, which can be of locally aggressive single or multiple lesions with a metasta… |
| ECT | Doneley et al · Journal of Exotic Pet Medicine | 2022 | Hayvan Çalışması | Hücre Kültürü | Sisplatin Hücre İçi Birikiminin Artması, Bleomisin Hücre İçi Birikiminin Artması | – / 1 | ElectroVET EZ | sisplatin · intratümöral | tam yanıt 1 adet (1 lezyon) | Background: Bearded dragons (Pogona vitticeps) are one of the most popular reptile pets globally. As their longevity increases with better care and nutrition, conditions common to many older… |
| ECT | Moretti et al · Front Vet Sci | 2022 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | Cliniporator | bleomisin · intravenöz | – | Electrochemotherapy (ECT) is a highly developed treatment for many solid tumours that provides good local control in 80% of neoplasms in dogs. ECT can be used to treat different types of tum… |
| ECT | Tellado et al · Cancer Drug Resist | 2022 | Hayvan Çalışması | Hayvan (İn Vivo) | Elektrot Geometrisi ve Yerleşimi, Bleomisin Hücre İçi Birikiminin Artması | – | EPV-200 | bleomisin · intravenöz | nesnel yanıt 80% (15 hasta) | Aim: Cutaneous squamous cell carcinoma (cSCC) is a common disease in patients exposed to UV-light and human papillomavirus. Electrochemotherapy, a well-established treatment modality with mi… |
| ECT | Dos Anjos et al · Life (Basel) | 2021 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – / 18 | Electroporator LC BK-100 | bleomisin · intravenöz | – | Canine cutaneous squamous cell carcinoma (SCC) is the most common type of skin cancer in tropical countries and is generally associated with exposure to solar ultraviolet light. It has a low… |
| ECT | Valenti et al · Open Vet J | 2021 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | Onkodisruptor | bleomisin · hem intravenöz hem intratümöral | nesnel yanıt 60% (10 hasta) | Background: Electrochemotherapy (ECT) combines the administration of anticancer drugs with the delivery of electric pulses, thus increasing the drug uptake through the cell membranes, result… |
| ECT | Brloznik et al · Front Vet Sci | 2021 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA), İnterlökin-12 Aracılı İmmün Uyarım | – / 12 | – | bleomisin · intravenöz | tam yanıt 7 adet (12 lezyon) | Electrochemotherapy (ECT) and/or gene electrotransfer of plasmid DNA encoding interleukin-12 (GET pIL-12) are effective treatments for canine cutaneous, subcutaneous, and maxillofacial tumor… |
| Gen ET | Pavlin et al · SVR | 2021 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – | Cliniporator | bleomisin · intravenöz | – | A 15-year- old male castrated English setter was presented for evaluation of a rapidly growing oral mass. Patient’s history was otherwise unremarkable, except of moderate proteinuria of 5 ye… |
| ECT | Simčič et al · Vet Sci | 2021 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Darbe Parametrelerinin Optimizasyonu | 61 | – | – | – | Feline squamous cell carcinoma (SCC) is currently treated with surgery, radiation therapy and electrochemotherapy (ECT). Both the efficacy and/or safety of ECT were evaluated as a sole thera… |
| ECT | Spugnini et al · Open Vet J | 2021 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması, Kas Kasılması ve Anestezi Gereksinimi | – / 16 | Onkodisruptor | sisplatin · intratümöral | – | Background: Electrochemotherapy (ECT) promotes the increased uptake of antitumor agents through the administration of permeabilizing electric pulses, thus enhancing chemotherapy effectivenes… |
| ECT | Spugnini et al · Open Vet J | 2020 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | Onkodisruptor | bleomisin · intravenöz | genel sağkalım 985 gün | Background: fFeline injection-site sarcomas (FISSs) are mesenchymal tumors that can occur in cats after injections of different medical agents and are easily prone to recurrence. Aim: The ai… |
| ECT | Dos Anjos et al · Sci Rep | 2020 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 66 | Onkodisruptor | bleomisin · intravenöz | tam yanıt 10 adet (24 lezyon) | Cutaneous squamous cell carcinoma (cSCC) is one of the most common skin tumors in cats due to chronic exposure to ultraviolet light. Local treatments such as electrochemotherapy (ECT) promot… |
| Kalsiyum EP | Frandsen · Animals (Basel) | 2020 | Hayvan Çalışması | Hayvan (İn Vivo) | Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Darbe Parametrelerinin Optimizasyonu | – / 32 | Cliniporator | kalsiyum klorür · intratümöral | tam yanıt 22% (27 lezyon) | Sarcoids are common equine skin tumors where the risk of recurrence after treatment is high, and better treatment options are warranted. Calcium electroporation is a novel anti-cancer treatm… |
| Gen ET | Milevoj et al · Vet Med Sci | 2020 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – | – | diğer | yaşam kalitesi 7.4 skor (44 hasta) | The aim of this study was to evaluate the owners' perception of health-related quality of life (HRQoL) of dogs after treatment with electrochemotherapy (ECT) alone or combined with interleuk… |
| ECT | Tellado et al · Radiol Oncol | 2020 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | BTX ECM830 | bleomisin · intravenöz | nesnel yanıt 70.1% (67 hasta) | Background Oral malignant melanoma is the most common, but aggressive oral cancer in dogs with poor prognosis. Electrochemotherapy (ECT) has therapeutic potential in such tumors as effective… |
| ECT | dos Anjos et al · Data Brief | 2020 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | LC-BK100, Onkodisruptor | sisplatin · intratümöral | tam yanıt 3 adet (4 hasta) | Over the past 15 years, lipophobic drugs, such as bleomycin and cisplatin, have been used combined with electroporation, which promotes their uptake through the cell membrane. The present da… |
| ECT | Boncea et al · Vet Record Case Reports | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 24 | Electrovet S13 | sisplatin · intratümöral | tam yanıt 100% (24 lezyon) | Canine squamous cell carcinoma (cSCC) is the second most common cutaneous neoplasm in dogs. Treatment options are limited. Electrochemotherapy (ECT) has been proposed as an alternative treat… |
| Kalsiyum EP | Dos Anjos et al · Acta Scientiae. Vet. | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Nekroz ve Nekroptoz | – / 3 | LC BK-100 | bleomisin · intravenöz | tam yanıt 1 adet (3 lezyon) | Background: Calcium electroporation (CaEP) is a novel therapeutic treatment that has been studied for cancer due to its selective killing cancer cells by necrosis and danger signals. Besides… |
| ECT | Dos Anjos et al · Sci Rep | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Apoptoz İndüksiyonu | – / 18 | LC BK-100 | bleomisin · intravenöz | – | Canine cutaneous squamous cell carcinoma (cSCC) is the most common skin cancer in dogs, and, due to its low metastatic rate, local treatments, such as electrochemotherapy (ECT), promote dise… |
| Kalsiyum EP | Galant et al · Bioelectrochemistry | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Nekroz ve Nekroptoz, Reversible Membran Permeabilizasyonu | – / 16 | Electrovet S13 | kalsiyum klorür · intratümöral | – | Electrochemotherapy (ECT) is an anticancer bioelectrochemical therapy where electrical field pulses (electropermeabilization) increase intracellular concentration of antitumor drugs. The pro… |
| Gen ET | Milevoj et al · Res Vet Sci | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – | Cliniporator, MEA | bleomisin · intravenöz | nesnel yanıt 67% (9 hasta) | The aim of this study was to evaluate the safety and efficacy of the combination of electrochemotherapy (ECT) with bleomycin and gene electrotransfer (GET) of plasmid encoding canine interle… |
| ECT | Moura et al · Revista Brasileira de Higiene e Sanidade Animal | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – / 1 | – | – · intratümöral | – | O mastocitoma é uma neoplasia de células redondas frequentemente encontrado em cães, correspondendo entre 7% e 21% das neoplasias cutâneas. Este trabalho teve como objetivo relatar as altera… |
| ECT | Simčič et al · Vet Comp Oncol | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | Cytopulse Oncovet, Cytopulse PA4000 | bleomisin · intravenöz | tam yanıt 8 adet (11 hasta) | Non-tonsillar squamous cell carcinoma (ntSCC) is a common and locally aggressive oral tumour in dogs. The treatments of choice are currently surgery and radiotherapy. Electrochemotherapy (EC… |
| ECT | Spugnini et al · Open Vet J | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | Onkodisruptor | bleomisin · hem intravenöz hem intratümöral | tam yanıt 26 adet (30 hasta) | Electrochemotherapy (ECT) couples the administration of anticancer drugs with the delivery of electric pulses that increase the drug uptake through the cell membranes, thus resulting in an i… |
| ECT | Tellado et al · – | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | BTX ECM830 | bleomisin · intravenöz | nesnel yanıt 100% (11 hasta) | Electrochemotherapy is a treatment modality which has been increasingly used in veterinary and human medicine for treating cutaneous and subcutaneous tumors. In this prospective work we eval… |
| Gen ET | Thalmensi · Oncotarget | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | – | Cliniporator, Agilepulse® in vivo system electroporator | plazmid DNA · intratümöral | – | Telomerase reverse transcriptase (TERT) is highly expressed in more than 90% of canine cancer cells and low to absent in normal cells. Given that immune tolerance to telomerase is easily bro… |
| ECT | Anjos et al · – | 2018 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Apoptoz İndüksiyonu | – / 18 | LC BK-100 | diğer · intravenöz | genel sağkalım 180 gün (11 hasta) | Canine cutaneous squamous cell carcinoma (cSCC) is the most common skin cancer in dogs, and due to its low metastatic rate, local treatments such as electrochemotherapy (ECT) promote disease… |
| ECT | Dos Anjos et al · Vet Record Case Reports | 2018 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 1 | LC BK-100 | bleomisin · intravenöz | tam yanıt 1 gün (1 hasta) | Canine trichoblastoma is a benign tumour derived from the trichoblastic epithelium, commonly affecting the head and neck and, less commonly, the limbs and trunk. Herein, the authors report a… |
| Gen ET | Impellizeri et al · J Transl Med | 2018 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | – | Vet-ePorator™ | plazmid DNA · intratümöral | genel sağkalım 64.5 hafta (17 hasta) | Background: we have recently shown that Tel-eVax, a genetic vaccine targeting dog telomerase (dTERT) and based on Adenovirus (Ad)/DNA Electro-Gene-Transfer (DNA-EGT) technology can induce st… |
| IRE | Latouche et al · Technol Cancer Res Treat | 2018 | Hayvan Çalışması | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü | – / 3 | VoltMed HFIRE-waveform generator, blunt-tip electrodes | – | – | High-frequency irreversible electroporation is a nonthermal method of tissue ablation that uses bursts of 0.5- to 2.0-microsecond bipolar electric pulses to permeabilize cell membranes and i… |
| ECT | Cunha et al · Cienc. Rural | 2017 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | – | bleomisin · intravenöz | tam yanıt 14 gün (3 hasta) | : Extramedullary plasmacytomas (EPs) are responsible for 2.5% of neoplasms in dogs. They are solitary, smooth, elevated, pink or red nodules, of 1 to 2cm in diameter. Cutaneous and oral extr… |
| Gen ET | Salvadori et al · Radiol Oncol | 2017 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA), İnterlökin-12 Aracılı İmmün Uyarım | – / 11 | Cliniporator | sisplatin · intratümöral | tam yanıt 7 adet (11 hasta) | Background: The study was aimed to characterize tumor response after combined treatment employing electrochemotherapy with IL-12 gene electrotransfer in dogs with spontaneous mast cell tumor… |
| ECT | Kulbacka et al · SVR | 2017 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 1 | BTX ECM830 | bleomisin · hem intravenöz hem intratümöral | tümör hacmi değişimi 140.11 cm³ | Oral melanomas commonly occur in elderly dogs resulting in darkly pigmented areas of the mouth, tongue and gums. The main object of this study was a severe melanoma diagnosed in the jaw of a… |
| ECT | Maglietti et al · Radiol Oncol | 2017 | Hayvan Çalışması | Hayvan (İn Vivo) | Elektrot Geometrisi ve Yerleşimi | – | BTX ECM830 | bleomisin · intravenöz | nesnel yanıt 91% (11 hasta) | Background: Nasal cavity tumors are usually diagnosed late, when they already have infiltrated adjacent tissues thus requiring very aggressive treatments with serious side effects. Here we u… |
| Gen ET | Cemazar et al · Vet Comp Oncol | 2016 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – / 18 | Cliniporator | diğer · intratümöral | nesnel yanıt 83% (18 lezyon) | Electrochemotherapy combined with peritumoral interleukin-12 (IL-12) gene electrotransfer was used for treatment of mast cell tumours in 18 client-owned dogs. Local tumour control, recurrenc… |
| Gen ET | Cicchelero et al · Vet Comp Oncol | 2016 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – | Agile Pulse generator | plazmid DNA · intratümöral | – | Interleukin 12 (IL-12) is a powerful immunostimulatory cytokine with a strong antitumoural activity. In this work, the immunological, anti-angiogenic and clinical effects of three consecutiv… |
| Gen ET | Maglietti et al · European Journal of Cancer | 2016 | Hayvan Çalışması | Hayvan (İn Vivo) | Apoptoz İndüksiyonu, Gen Elektrotransferi (Plazmid DNA) | – | – | plazmid DNA · diğer yol | lokal kontrol 4 adet (5 hasta) | Immune checkpoint inhibitor Programmed Death Ligand 1 (PD-L1) is upregulated in many malignancies which often correlates with unfavorable prognosis. PD-L1 on cancer cells can induce an “exha… |
| ECT | Lowe et al · Vet Comp Oncol | 2016 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | Cytopulse PA4000, Cytopulse Oncovet, Cliniporator, Gehl Needle electrodes | bleomisin · intravenöz | tam yanıt 80% (15 hasta) | To describe the results of electrochemotherapy (ECT) in dogs with mast cell tumours (MCTs) either as first line therapy or as an adjuvant to surgery. The treatment combines administration of… |
| Diğer EP | Souza et al · J Vet Pharmacol Ther | 2016 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | BTX ECM830 | bleomisin | hücre canlılığı 12% | Electroporation is a method used to deliver poorly permeant chemotherapeutic drugs to tumor cells, potentiating the cytotoxic effects of drugs and overall clinical response. Despite existing… |
| ECT | Suzuki et al · Artif Organs | 2016 | Hayvan Çalışması | Hayvan (İn Vivo) | Elektrot Geometrisi ve Yerleşimi, Bleomisin Hücre İçi Birikiminin Artması | – | BTX ECM830 | bleomisin · topikal | – | Electrochemotherapy is a new modality of local cancer treatment that increases the delivery of chemotherapy drugs into tumor cells by applying intense electric fields. This novel electrochem… |
| ECT | Tozon et al · Vet Rec | 2016 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 69 | Jouan GHT 1287, Cliniporator | sisplatin · intratümöral | tam yanıt 92.3% (52 lezyon) | The aim of our study was to evaluate the efficacy of electrochemotherapy (ECT) with cisplatin as a single or adjuvant treatment for sarcoids in equids. Different treatment options with diffe… |
| ECT | Tozon et al · J Vis Exp | 2016 | Hayvan Çalışması | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, Bleomisin Hücre İçi Birikiminin Artması | – | – | bleomisin · hem intravenöz hem intratümöral | – | Electrochemotherapy (ECT) is a local approach which is used for treating solid tumors of different histologies. Its mechanism is based on cell membrane permeabilization by means of "electrop… |
| ECT | Spugnini et al · J Vet Intern Med | 2015 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Kas Kasılması ve Anestezi Gereksinimi | – | Chemipulse III | bleomisin · intravenöz | – | Background: Advanced carcinoma of the head represents a substantial health problem in cats for local control and overall survival. Objectives: Evaluate the capability of electrochemotherapy … |
| IRE | Rossmeisl et al · J Neurosurg | 2015 | Hayvan Çalışması | Hayvan (İn Vivo) | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | 7 / 7 | NanoKnife | – | – | Object: Irreversible electroporation (IRE) is a novel nonthermal ablation technique that has been used for the treatment of solid cancers. However, it has not been evaluated for use in brain… |
| ECT | F.H. Maglietti et al · J. Anal. Oncol. | 2014 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Hemostaz ve Kanama Kontrolü | – / 1 | BTX ECM830 | bleomisin · intravenöz | tümör hacmi değişimi 83% | Background: Electrochemotherapy is a novel tumor treatment routinely used for cutaneous and subcutaneous tumors in human patients in the European Union since 2006. Here we used it to treat a… |
| Diğer EP | Riccardo et al · Clin Cancer Res | 2014 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | – | Cliniporator | plazmid DNA · intratümöral | – | Purpose: Due to the many similarities with its human counterpart, canine malignant melanoma (cMM) is a valuable model in which to assess the efficacy of novel therapeutic strategies. The mod… |
| ECT | Tellado et al · Case Reports in Veterinary Medicine | 2014 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Kas Kasılması ve Anestezi Gereksinimi | – / 1 | BTX ECM830 | bleomisin · intravenöz | tam yanıt 100% | A case of a canine oral eosinophilic granuloma in a 14-year-old female crossbred is described. The dog was presented with a history of ptyalism, halitosis, local pain, decreased appetite, an… |
| ECT | Tozon et al · J Feline Med Surg | 2013 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | Cliniporator | bleomisin · intravenöz | – | The aim of this study was to evaluate the efficacy and safety of electrochemotherapy (ECT) with bleomycin for treatment of squamous cell carcinoma (SCC) in cats. Between March 2008 and Octob… |
| Belirlenmedi | Gavazza et al · Hum Gene Ther | 2013 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | – | plazmid DNA · intratümöral | genel sağkalım 76.1 hafta (21 hasta) | Client-owned pet dogs represent exceptional translational models for advancement of cancer research because they reflect the complex heterogeneity observed in human cancer. We have recently … |
| ECT | Scacco et al · Journal of Equine Veterinary Science | 2013 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 2 | Chemipulse III, Chemipulse III portable electroporator | sisplatin · intratümöral | – | A 25-year-old gelding sport horse was referred for the treatment of recurring bilateral anal amelanotic melanoma. On physical examination, the horse presented bilateral poorly delimited peri… |
| ECT | Spugnini et al · J Vet Intern Med | 2011 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | Chemopulse | sisplatin · intratümöral | hastalıksız sağkalım 78% (37 hasta) | Background: Electrochemotherapy (ECT) couples the administration of anticancer drugs with the delivery of electric pulses that increase the drug uptake through the cell membranes, resulting … |
| Gen ET | Pavlin · Radiol Oncol | 2011 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – / 11 | – | plazmid DNA · intratümöral | – | Background: Mast cell tumors (MCT) are the most common malignant cutaneous tumors in dogs with extremely variable biological behaviour. Different treatment approaches can be used in canine c… |
| ECT | Spugnini et al · Journal of Equine Veterinary Science | 2011 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – | Chemipulse III, Chemipulse III portable electroporator | sisplatin · intratümöral | tümör hacmi değişimi 50% | A 22-year-old Camargue mare was referred for showing signs of discomfort during chewing, building up of food in the mouth, and foul odor from the mouth. On physical examination, the mare pre… |
| ECT | Tamzali et al · Equine Vet J | 2011 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması, Reversible Membran Permeabilizasyonu | – / 194 | BetaTech, PS 15 | sisplatin · intratümöral | tam yanıt 0.979 oran (48 hayvan) | Reasons for performing study: Sarcoids are the commonest form of equine skin tumour. Several therapeutic measures have been described but none is considered to be universally effective. Elec… |
| ECT | Reed et al · Cancer Gene Ther | 2010 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, İnterlökin-12 Aracılı İmmün Uyarım | – | BTX ECM830, hexagonal array of six-needle electrodes | bleomisin · intratümöral | tam yanıt 3 adet (6 hasta) | On the basis of superior outcomes from electrochemogene therapy (ECGT) compared with electrochemotherapy in mice, we determined the efficacy of ECGT applied to spontaneous canine neoplasms. … |
| ECT | Reed et al · Cancer Gene Ther | 2010 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, İnterlökin-12 Aracılı İmmün Uyarım | – / 6 | BTX ECM830 | bleomisin · intratümöral | tam yanıt 3 adet (6 hasta) | On the basis of superior outcomes from electrochemogenetherapy (ECGT) compared with electrochemotherapy in mice, we determined the efficacy of ECGT applied to spontaneous canine neoplasms. I… |
| ECT | Tozon et al · Acta vet. (Beogr.) | 2010 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – / 66 | Jouan GHT 1287, Cliniporator | sisplatin · intratümöral | nesnel yanıt 93.9% (66 lezyon) | Perianal tumors are common in older male dogs. The usefulness of electrochemotherapy in veterinary oncology has already been demonstrated by clinical studies on different malignancies in com… |
| Diğer EP | Chuang et al · Int J Cancer | 2009 | Hayvan Çalışması | Hayvan (İn Vivo) | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | – | BTX ECM830, Electro Square Porator ECM 830 pulse generator | plazmid DNA · intratümöral | – | Interleukin-12 (IL-12) is effective in treating many types of rodent tumors, but has been unsuccessful in most human clinical trials, suggesting that animal models of more clinical relevance… |
| ECT | Kodre et al · In Vivo | 2009 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 12 | IGEA plate electrodes | sisplatin · intratümöral | tam yanıt 62.5% (9 hasta) | Unlabelled: The aim of this study was to evaluate the effectiveness of local treatment electrochemotherapy (ECT) with cisplatin and to compare it with effectiveness of surgery for treatment … |
| ECT | Spugnini et al · Vet J | 2009 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – / 9 | chemopulse | bleomisin · intratümöral | tam yanıt 7 adet (9 hasta) | Squamous cell carcinomas (SCC) of the skin are commonly described in cats. Reported treatments include surgery, radiation therapy and photodynamic therapy. This preliminary study reports on … |
| ECT | Spugnini et al · J Exp Clin Cancer Res | 2008 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | – | Chemopulse | bleomisin · intratümöral | tam yanıt 3 adet (3 hasta) | Sticker's sarcoma (also known as transmissible venereal tumor) is a horizontally transmitted neoplasm of the dog, that is passed with coitus. It is a locally aggressive tumor with a low tend… |
| ECT | Spugnini et al · In Vivo | 2007 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt | – | Chemopulse | bleomisin · intratümöral | – | Electrochemotherapy (ECT) is a new therapeutical technique that combines the administration of trains of biphasic pulses with the local application of poorly permeant anticancer molecules, t… |
| ECT | Spugnini et al · J Exp Clin Cancer Res | 2007 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | – | Chemopulse | bleomisin | – | Perianal tumors (adenoma and carcinoma of the hepatoid glands) are frequently reported in veterinary literature. They are locally aggressive tumors with a low tendency to metastatic spread. … |
| ECT | Spugnini et al · J Exp Clin Cancer Res | 2007 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | – | Chemopulse | bleomisin · intratümöral | tam yanıt 6 adet (6 hasta) | Non Hogdkin's lymphoma is the commonest malignant neoplasm in humans and in pets. Treatments include systemic chemotherapy eventually combined with radiation therapy. Radiation therapy is al… |
| ECT | Spugnini et al · J Transl Med | 2007 | Hayvan Çalışması | Hayvan (İn Vivo) | Apoptoz İndüksiyonu, Nekroz ve Nekroptoz | – | CHEMOPULSE | bleomisin · intratümöral | – | Electrochemotherapy (ECT) is a novel anticancer therapy that is currently being evaluated in human and pet cancer patients. ECT associates the administration of an anti-tumor agent to the de… |
| ECT | Spugnini et al · Anticancer Res | 2006 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Darbe Parametrelerinin Optimizasyonu | – / 28 | Chemopulse, Chemopulse clinical electroporation equipment | bleomisin · intratümöral | genel sağkalım 85% (28 hasta) | Background: Electrochemotherapy (ECT) is a novel anticancer therapy that combines the delivery of trains of appropriate waveforms with the local administration of chemotherapy agents. The pu… |
| ECT | Tozon et al · Anticancer Res | 2005 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – / 26 | Jouan GHT 1287 | sisplatin · intratümöral | nesnel yanıt 82% (26 lezyon) | Background: Electrochemotherapy is an antitumor therapy that utilizes locally-delivered, short intense direct current electric pulse to the tumor nodule plus chemotherapy. The aim of the pre… |
| ECT | Rols et al · Bioelectrochemistry | 2002 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 10 | Jouan Electropulsator, PS 15 | sisplatin · intratümöral | tam yanıt 100% (10 lezyon) | Sarcoids are skin spontaneous tumours detected in horses. It can be cured by chemotherapy by using cisplatin. A multisequence treatment must be performed. Problems are present due to the poo… |
| ECT | Tozon et al · Anticancer Res | 2001 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | – | – | – | The aim of this study was to introduce electrochemotherapy with cisplatin into veterinary medicine, where there is a need for inexpensive and effective treatment of cutaneous and subcutaneou… |
| ECT | Mir et al · Br J Cancer | 1997 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | PS 15, CELTEM MKO generator | bleomisin · intravenöz | genel sağkalım 6.1 ay (12 hasta) | Electrochemotherapy combines bleomycin and local electric pulses that allow cell permeabilization and free access of bleomycin to its intracellular target. We report the first veterinarian c… |
| ECT | Suzuki et al · Artif Organs | 2017 | İn Siliko / Modelleme | Hesaplamalı Model | Elektrik Alan Dağılımı ve Modellemesi, Reversible Membran Permeabilizasyonu | – / 1 | BTX ECM830 | bleomisin · intravenöz | tümör hacmi değişimi 0 cm³ (1 hasta) | Electrochemotherapy (EQT) is a local cancer treatment well established to cutaneous and subcutaneous tumors. Electric fields are applied to biological tissue in order to improve membrane per… |
| ECT | Suzuki et al · Artif Organs | 2014 | İn Siliko / Modelleme | Hesaplamalı Model | Elektrik Alan Dağılımı ve Modellemesi, Elektrot Geometrisi ve Yerleşimi | – | BTX ECM830 | bleomisin · intravenöz | – | Electrochemotherapy is a combination of high electric field and anticancer drugs. The treatment basis is electroporation or electropermeabilization of the cell membrane. Electroporation is a… |
| ECT | Rangel · Artif Organs | 2018 | Editöryal / Mektup | Hayvan (İn Vivo) | – | – | – | bleomisin | tam yanıt 1 adet (1 hasta) | , First of all, thank you for your inquiries and your careful reading of our published article (1). The following is a response to valuable questions in our work: 1. Nasal carcinoma (TVT)—Ye… |
| ECT | Osorio‐Morales et al · Artif Organs | 2017 | Editöryal / Mektup | Hayvan (İn Vivo) | – | – | – | – | – | , We refer you to the study entitled “Novel Application for Electrochemotherapy: Immersion of Nasal Cavity in Dog” in which, Suzuki et al. (1) report the successful chemotherapeutic treatmen… |
| ECT | Salmoral et al · JFMS Open Rep | 2025 | Düzeltme / Erratum | Hayvan (İn Vivo) | – | – | – | sisplatin · intratümöral | – | [This corrects the article DOI: 10.1177/20551169231213499.]. |
| ECT | Dos Anjos et al · Sci Rep | 2021 | Düzeltme / Erratum | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | – | – | bleomisin | – | An amendment to this paper has been published and can be accessed via a link at the top of the paper. |
Bu süzgeçlerle eşleşen yayın yok.
Sınırlılıklar
Yayın hacmi klinik etkinlik ya da kanıt kalitesi değildir. Alanda ne kadar ve hangi türde literatür bulunduğunu tarif eder; tedavinin ne kadar kanıtlandığını, kılavuz onayını ya da regülasyon durumunu göstermez.
Hasta toplamları benzersiz hasta sayısı değildir. Aynı kohort birden fazla yayında raporlanmış olabilir; toplamlar bir meta-analiz değildir.
Korpusun nasıl derlendiği, kademe eşikleri, klinik yayın tanımı ve yöntemlerin birbirinden ayrı sayılması: Literatür Haritası.