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Klinik Kanıt 135 yayın

Kardiyak Pulsed-Field Ablasyon

Onkoloji Dışı Uygulamalar

Kardiyak pulsed-field ablasyon, atriyal fibrilasyon tedavisinde irreversibl elektroporasyonu kullanır ve elektroporasyonun onkoloji dışındaki en geniş klinik uygulamasıdır. Doku seçiciliği sayesinde özofagus ve frenik sinir gibi komşu yapıları koruması, aynı biyofiziksel ilkenin tümör ablasyonunda da aranan özelliğidir. Bu alan portalın onkolojik kapsamı dışındadır ve endikasyon manzarasında yer almaz; korpusta bağlam olarak bulunur.

135toplam yayın
54klinik çalışma
26preklinik çalışma
39derleme
2007–2026yayın aralığı

Rejime Göre Kanıt Durumu

İrreversible elektroporasyon (IRE-ECT)

135yayın
54klinik
26preklinik

Klinik Kanıt

2007–2026 · Rutin Klinik Kullanımda

Bu Alanda Raporlanan Mekanizmalar

Terimler, yayın özetleri üzerinde otomatik eşleştirmeyle saptanmıştır; rakam terimin geçtiği yayın sayısını gösterir.

İrreversible Por Oluşumu ve Hücre Ölümü 133 Sinir ve Damar Yapılarının Korunması 30 Reversible Membran Permeabilizasyonu 29 Kas Kasılması ve Anestezi Gereksinimi 11 Doku İletkenliği ve Empedans Değişimi 10 Elektrik Alan Dağılımı ve Modellemesi 7 Nekroz ve Nekroptoz 6 Darbe Parametrelerinin Optimizasyonu 6 Termal Etki ve Joule Isınması 4 Elektrot Geometrisi ve Yerleşimi 4 Apoptoz İndüksiyonu 4 Mitokondriyal Disfonksiyon ve Oksidatif Stres 2

Çalışma Tipi Dağılımı

Çubuk uzunluğu en kalabalık çalışma tipine göre ölçeklenmiştir; yüzde ise alanın tamamındaki payı verir. Renk, çalışma tipinin kanıt basamağını gösterir; kanıt haritasındaki ile aynı ölçek.

Çalışma tipiYayınBu alandaki payı
Randomize Klinik Çalışma2
%1
Prospektif Klinik Çalışma4
%3
Klinik Çalışma40
%30
Retrospektif Klinik Çalışma2
%1
Vaka Serisi6
%4
Vaka Raporu2
%1
Sistematik Derleme / Meta-Analiz28
%21
Derleme11
%8
Hayvan Çalışması25
%19
İn Vitro Çalışma1
<%1
Ön Baskı7
%5
Editöryal / Mektup3
%2
Düzeltme / Erratum1
<%1
Protokol2
%1
Belirtilmemiş1
<%1

Literatür Kanıt Tablosu

135 yayın, kanıt gücü sırasına göre listelenmiştir. Başlığa tıklayarak künye, mekanizma ve tam özet çekmecesini açabilirsiniz.

RejimYayınYılÇalışma tipiModelMekanizmaÖzet
İrreversible
Dashwood et al · Pacing Clin Electrophysiol
2025Randomize Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüIntroduction: Atrial fibrillation (AF) ablation often involves large-diameter catheters, posing challenges for post-procedure hemostasis and discharge. The impact of Perclose Prostyle vascul…
İrreversible
Younis et al · JACC Clin Electrophysiol
2024Randomize Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Doku İletkenliği ve Empedans DeğişimiBackground: The efficacy of pulsed field ablation (PFA) for redo procedures is unknown. Objectives: In this study, the authors aimed to evaluate the effectiveness of PFA when performing PFA …
İrreversible
Keelani et al · JACC Clin Electrophysiol
2026Prospektif Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) may overcome key limitations of radiofrequency ablation (RFA) when treating premature ventricular contractions (PVCs) in anatomically complex regions …
İrreversible
Liu et al · J Interv Card Electrophysiol
2026Prospektif Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBACKGROUND: Pulsed field ablation (PFA) is an emerging innovative technology for treating paroxysmal atrial fibrillation (PAF), featured by its superior speed, accuracy, and reduced risk to …
İrreversible
Wong et al · JACC Clin Electrophysiol
2026Prospektif Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Pentaspline pulsed field ablation (PFA) is an emerging technology delivering ultra-short bursts of ablative high electrical field energy. There are limited studies on atrial fibr…
İrreversible
Eckart et al · Heart Rhythm O2
2025Prospektif Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) has revolutionized catheter ablation procedures in terms of safety, efficiency, and efficacy. Streamlined zero-exchange workflows with therapy sheath …
İrreversible
Abeln et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Research on pulsed field ablation (PFA) systems for atrial fibrillation (AF) ablation has expanded rapidly in recent years, particularly with respect to short-term safety and effi…
İrreversible
Askarinejad et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground Pulsed-field ablation (PFA) is an emerging non-thermal energy modality that induces irreversible electroporation, selectively affecting myocardial cells while sparing surrounding …
İrreversible
Bistriceanu et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Current atrial fibrillation (AF) guidelines and expert consensus documents from major societies discuss early arrhythmia recurrence (ER) within the first 3 months after catheter a…
İrreversible
Bobosik et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Kas Kasılması ve Anestezi GereksinimiIntroduction In the Czech Republic, the majority of catheter ablation procedures for atrial fibrillation (AF) are currently performed using pulsed-field (PF) ablation. Management of older AF…
İrreversible
Ferro et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground Pulsed field ablation (PFA) has demonstrated comparable efficacy to radiofrequency ablation (RFA) in the treatment of atrial fibrillation (AF), with enhanced safety due to its car…
İrreversible
Hornof et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Kas Kasılması ve Anestezi GereksinimiBackground There is limited data regarding the use of pulsed-field ablation (PFA) for mitral isthmus (MI) ablation in patients with non-paroxysmal atrial fibrillation (AF). Purpose To assess…
İrreversible
Huegl et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Transseptal puncture (TSP) for atrial fibrillation (AF) ablation in patients with septal occluder devices (SODs) is technically challenging because of altered septal anatomy and l…
İrreversible
Keelani et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıCatheter ablation is the most effective therapy in patients with atrial tachycardia.1 Right atrial tachycardia may be challenging because of proximity to the phrenic nerve and sinus node, li…
İrreversible
Latini et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüAims Pulsed field ablation (PFA) has recently emerged as a promising alternative to conventional energy sources (ES) for atrial fibrillation (AF) ablation. However, comparative data between …
İrreversible
Makdah et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Pulsed field ablation (PFA) has emerged as a non-thermal ablation technology capable of producing myocardial lesions while minimizing collateral tissue injury. Although extensivel…
İrreversible
Makdah et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground/Introduction The superior vena cava (SVC) has been identified as a non-pulmonary vein trigger in atrial fibrillation (AF) and SVC isolation has been suggested for improvement of l…
İrreversible
Marino et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Experience on pulsed field ablation (PFA) in patients with a prior left atrial appendage (LAA) occlusion device is limited. Purpose This study aimed to assess the feasibility and …
İrreversible
Mills et al · J Cardiovasc Electrophysiol
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed-field ablation (PFA) has transformed atrial fibrillation (AF) ablation, but how the early patient experience compares with thermal techniques remains unclear. This study a…
İrreversible
Mitacchione et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Real-world evidence assessing the learning curve and procedural efficiency of the pentaspline pulsed-field ablation (PFA) system with novel mapping-integrated capabilities remains…
İrreversible
Miyama et al · J Cardiovasc Electrophysiol
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Little is known about the efficacy and safety of pulsed field ablation (PFA) for repeat ablation procedures for patients with recurrent atrial fibrillation (AF) after pulmonary v…
İrreversible
Pannone et al · Europace
2026Klinik ÇalışmaİnsanReversible Membran Permeabilizasyonu, Darbe Parametrelerinin OptimizasyonuBackground Reversible electroporation (PFREV) has recently been described as a useful tool for mapping macroreentrant atrial tachycardias, allowing identification of the critical isthmus bef…
İrreversible
Roth et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Early rhythm control enhances cardiovascular outcomes in patients with atrial fibrillation (AF) and significant comorbidities. However, most evidence stems from antiarrhythmic dru…
İrreversible
Schiavone et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüAims Data on pulsed-field ablation (PFA) for atrial fibrillation (AF) in patients with heart failure (HF) are limited. To evaluate clinical outcomes of PFA in patients with AF and HF, strati…
İrreversible
Szeplaki et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüIntroduction Pulsed field ablation (PFA) has emerged as a leading catheter ablation modality for the treatment of atrial fibrillation (AF), producing durable lesions in the myocardium. Long-…
İrreversible
Tokutake et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Pulsed field ablation (PFA) selectively targets myocardial tissue while minimizing injury to surrounding structures. Although its safety and efficacy for pulmonary vein (PV) isola…
İrreversible
Valappil et al · Heart Rhythm
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Termal Etki ve Joule IsınmasıBackground: Pulsed field ablation (PFA) induces cell death predominantly through irreversible electroporation (IRE), a non-thermal mechanism. However, Joule heating during PFA delivery may r…
İrreversible
Zarebski et al · Europace
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Cavotricuspid isthmus (CTI) ablation is the cornerstone of catheter ablation for typical atrial flutter (AFL). Pulsed field ablation (PFA) has emerged as an alternative therapy fo…
İrreversible
van der Graaf et al · J Cardiovasc Electrophysiol
2026Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: While various pulsed field ablation (PFA) systems for atrial fibrillation (AF) ablation have become available in recent years, data comparing long-term efficacy outcomes remain l…
İrreversible
Badertscher et al · Europace
2025Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıRadiofrequency and cryoablation have been the standard energy sources for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF), whereas pulsed-field ablation (PFA) has em…
İrreversible
Duytschaever et al · JACC Clin Electrophysiol
2025Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Omny-IRE (A Study For Treatment of Paroxysmal Atrial Fibrillation [PAF] With the OMNYPULSE Catheter and the TRUPULSE Generator) evaluated safety and effectiveness of a novel larg…
İrreversible
Rodriguez-Riascos et al · Circ Arrhythm Electrophysiol
2025Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Cavotricuspid isthmus (CTI) ablation is frequently performed either as a standalone procedure or in combination with pulmonary vein isolation. With the rapid adoption of pulsed f…
İrreversible
Rossillo et al · Europace
2025Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Increased left atrial (LA) size in atrial fibrillation (AF) is associated with AF recurrence following ablation. Limited data exist on pulsed-field ablation (PFA) in patients with…
İrreversible
Woermann et al · Europace
2025Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Doku İletkenliği ve Empedans DeğişimiBackground Pulsed-field ablation (PFA) is a novel non-thermal atrial fibrillation (AF) ablation technique presumed safety benefits due to its tissue selectivity. However, the high-voltage el…
İrreversible
Reddy et al · Europace
2024Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüAims Pulsed field ablation (PFA) has significant advantages over conventional thermal ablation of atrial fibrillation (AF). This first-in-human, single-arm trial to treat paroxysmal AF (PAF)…
İrreversible
Schiavone et al · J Cardiovasc Electrophysiol
2024Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüIntroduction: Limited data exist on pulsed-field ablation (PFA) in patients with persistent atrial fibrillation (PeAF) undergoing left atrial posterior wall isolation (LAPWI). Methods: The A…
İrreversible
Turagam et al · Heart Rhythm
2024Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: During pulsed field ablation (PFA), electrode-tissue proximity optimizes lesion quality. A novel "single-shot" map-and-ablate spherical multielectrode PFA array catheter that is …
İrreversible
Anić et al · Europace
2023Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüAims Pulsed field ablation (PFA) has emerged as a promising alternative to thermal ablation for treatment of atrial fibrillation (AF). We report performance and safety using the CENTAURI™ Sy…
İrreversible
Kirstein et al · J Cardiovasc Electrophysiol
2023Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Termal Etki ve Joule IsınmasıIntroduction: Atrio-esophageal fistula after esophageal thermal injury (ETI) is one of the most devastating complications of available energy sources for atrial fibrillation (AF) ablation. P…
İrreversible
Verma et al · Circulation
2023Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground: Pulsed field ablation uses electrical pulses to cause nonthermal irreversible electroporation and induce cardiac cell death. Pulsed field ablation may have effectiveness comparab…
İrreversible
Reinsch et al · Heart Rhythm
2022Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) is a novel, nonthermal ablation modality that can ablate myocardial tissue with minimal effects on surrounding tissue. Preclinical data show an absenc…
İrreversible
Schmidt et al · Circ Arrhythm Electrophysiol
2022Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Kas Kasılması ve Anestezi GereksinimiBackground: Pulsed field ablation represents an energy source specific for ablation of cardiac arrhythmias including atrial fibrillation. The aim of the study was to describe the adoption an…
İrreversible
Cochet et al · Europace
2021Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıAims Extra-atrial injury can cause complications after catheter ablation for atrial fibrillation (AF). Pulsed field ablation (PFA) has generated preclinical data suggesting that it selective…
İrreversible
Kawamura et al · Europace
2021Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüAims We studied the extent/area of electrical pulmonary vein isolation (PVI) after either pulsed field ablation (PFA) using a pentaspline catheter or thermal ablation technologies. Methods a…
İrreversible
Nakatani et al · Europace
2021Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Hemostaz ve Kanama KontrolüAims Pulsed field ablation (PFA), a non-thermal ablative modality, may show different effects on the myocardial tissue compared to thermal ablation. Thus, this study aimed to compare the lef…
İrreversible
Reddy et al · J Am Coll Cardiol
2019Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Catheter ablation of atrial fibrillation using thermal energies such as radiofrequency or cryothermy is associated with indiscriminate tissue destruction. During pulsed field abl…
İrreversible
Al-slaimieh et al · Front Cardiovasc Med
2026Retrospektif Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre ÖlümüIntroduction: Pulsed field ablation (PFA) is a novel, non-thermal method for the treatment of atrial fibrillation (AF). We conducted this study, as part of one of the earliest reports origin…
İrreversible
Turagam et al · Circulation
2023Retrospektif Klinik Çalışmaİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground: Pulsed field ablation is a novel nonthermal cardiac ablation modality using ultra-rapid electrical pulses to cause cell death by a mechanism of irreversible electroporation. Unli…
İrreversible
Ballesteros et al · J Interv Card Electrophysiol
2026Vaka Serisiİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Kas Kasılması ve Anestezi GereksinimiBackground: The PulseSelect™ circular pulsed field ablation (PFA) catheter demonstrated excellent safety in its pivotal trial, but real-world evidence on its early adoption and implementatio…
İrreversible
Follesa et al · J Arrhythm
2026Vaka Serisiİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed-field ablation (PFA) is increasingly used for catheter ablation of atrial fibrillation (AF), but older patients remain underrepresented in clinical trials. This study aime…
İrreversible
Ha et al · J Arrhythm
2026Vaka Serisiİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Older patients have been under-represented in clinical trials of atrial fibrillation (AF) ablation. The safety of pulsed field ablation (PFA) in this cohort is not known. Methods…
İrreversible
Sawada et al · Heart Rhythm O2
2026Vaka Serisiİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) is a novel therapy for atrial fibrillation (AF) with myocardial selectivity and safety. The VARIPULSE catheter (variable-loop circular catheter [VLCC]…
İrreversible
Tilz et al · J Interv Card Electrophysiol
2026Vaka Serisiİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: The balloon-in-basket(BiB) pulsed field ablation(PFA) system integrates real-time electroanatomic mapping and contact sensing to streamline workflows, but clinical experience rem…
İrreversible
Wójcik et al · J Interv Card Electrophysiol
2026Vaka Serisiİnsanİrreversible Por Oluşumu ve Hücre ÖlümüPurpose: Pulsed-field ablation (PFA) is established for pulmonary vein isolation, but data on superior vena cava (SVC) isolation are limited. We assessed the feasibility and acute safety of …
İrreversible
Jadczyk et al · Eur Heart J Case Rep
2026Vaka Raporuİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground Pulmonary vein stenosis (PVS) is an uncommon but serious complication of atrial fibrillation (AF) ablation. Angioplasty with stent implantation is the standard treatment for sever…
İrreversible
Onuki et al · Pacing Clin Electrophysiol
2026Vaka Raporuİnsanİrreversible Por Oluşumu ve Hücre ÖlümüPulsed-field ablation (PFA) in patients with an implanted extravascular implantable cardioverter-defibrillator (EV-ICD) poses theoretical risks of electromagnetic interference or lead displa…
İrreversible
Ahmed et al · J Interv Card Electrophysiol
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBACKGROUND: Cryoballoon ablation (CBA) is a widely used method for pulmonary vein isolation (PVI), while Pulsed-Field ablation (PFA) is a newer, non-thermal technique that shows promise for …
İrreversible
Al Diab Al Azzawi et al · BMC Cardiovasc Disord
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBACKGROUND: Pulsed field ablation (PFA) is a non-thermal alternative to cryoballoon ablation (CBA) for pulmonary vein isolation in atrial fibrillation (AF). We compared their procedural effi…
İrreversible
Alnomani et al · J Arrhythm
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: With over 60 million cases worldwide, atrial fibrillation (AF) is one of the most common cardiac arrhythmias in adults. Pulsed-field ablation (PFA) has emerged as a significant a…
İrreversible
Arevalo et al · J Cardiovasc Electrophysiol
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüIntroduction: The conventional 3-month blanking period after atrial fibrillation (AF) ablation has been applied irrespective of energy modality. Pulsed field ablation (PFA), a nonthermal tec…
İrreversible
Bax et al · Heart Rhythm
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre ÖlümüPulsed field ablation (PFA) is emerging as an alternative to thermal ablation for pulmonary vein isolation (PVI) in atrial fibrillation, although PFA-specific complications have arisen. This…
İrreversible
Bokhari et al · Medicine (Baltimore)
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Atrial fibrillation (AF) remains the most common sustained cardiac arrhythmia. Pulsed field ablation (PFA) and cryoablation (CA) aim to isolate pulmonary veins and prevent AF rec…
İrreversible
Bregion et al · J Cardiovasc Dev Dis
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) has shown promising results for atrial fibrillation (AF), with efficacy comparable to established ablation techniques. High-power short-duration (HPSD…
İrreversible
Cao et al · Front Cardiovasc Med
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) and very high power short duration ablation (vHPSD) are new techniques for catheter ablation of atrial fibrillation that have been rapidly developed i…
İrreversible
Erzinger et al · J Interv Card Electrophysiol
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre ÖlümüBACKGROUND: The efficacy and safety of pulsed-field (PFA) ablation with zero/low-fluoroscopy (ZF/LF) approach is unclear with previous evidence limited to thermal technique. METHODS: PubMed,…
İrreversible
Ha et al · J Interv Card Electrophysiol
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre ÖlümüBACKGROUND: Limited real-world data exist regarding pulmonary vein (PV) and posterior wall (PW) durability after index pulsed field ablation (PFA) for atrial fibrillation (AF) in patients un…
İrreversible
Li et al · Pacing Clin Electrophysiol
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) is an emerging nonthermal ablation modality that can penetrate scar tissue more deeply. However, the evidence supporting its application in ventricula…
İrreversible
Li et al · BMC Cardiovasc Disord
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) has emerged as an innovative non-thermal approach with significant promise for treating atrial fibrillation (AF). However, comparative data between PF…
İrreversible
Mehta et al · J Interv Card Electrophysiol
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Cavotricuspid isthmus (CTI) dependent atrial flutter (AFL) is conventionally managed using radiofrequency catheter ablation. Pulsed field ablation (PFA) is an emerging non-therma…
İrreversible
Mojica et al · BMC Cardiovasc Disord
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia and a leading cause of stroke. Pulsed field ablation (PFA) emerges as a novel, non-thermal energy source offering m…
İrreversible
Oudih et al · Pacing Clin Electrophysiol
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıIntroduction: Pulsed-field ablation (PFA) is a novel, nonthermal modality for the treatment of atrial fibrillation (AF) that may reduce procedural complications compared with conventional th…
İrreversible
Pajareya et al · Pacing Clin Electrophysiol
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Pulse field ablation (PFA) is an emerging catheter ablation strategy for patients with atrial fibrillation (AF). Nonetheless, the safety and efficacy of PFA in elderly patients r…
İrreversible
Sawalha et al · Pacing Clin Electrophysiol
2026Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Fluoroscopy reduction has become a priority in electrophysiology to mitigate radiation exposure and the musculoskeletal burden of lead apron use. Pulsed field ablation (PFA) offe…
İrreversible
Villarreal et al · J Cardiovasc Electrophysiol
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground and aims: Pulsed field ablation (PFA) has emerged as a non-thermal alternative for pulmonary vein isolation (PVI), offering shorter procedural times and a favorable safety profile…
İrreversible
Wan et al · Sci Rep
2026Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüPulsed field ablation (PFA)-guided pulmonary vein isolation (PVI) has limited efficacy in treating persistent atrial fibrillation (AF) and requires additional substrate modification, but the…
İrreversible
Abbas et al · –
2025Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Pulsed field ablation (PFA) is an established modality for atrial fibrillation (AF) due to myocardial selectivity and reduced collateral injury. Its role in ventricular tachycard…
İrreversible
Arrighini et al · J Interv Card Electrophysiol
2025Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) is a novel, non-thermal technique for atrial fibrillation ablation that is currently under early investigation for paroxysmal supraventricular tachyca…
İrreversible
Barbosa et al · J Interv Card Electrophysiol
2025Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed-field ablation (PFA) has emerged as a potentially safer alternative to radiofrequency ablation (RFA). However, recent studies have raised concerns that PFA may induce hemo…
İrreversible
Marazzato et al · Prog Cardiovasc Dis
2025Sistematik Derleme / Meta-AnalizHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuPulsed field ablation (PFA) is a novel and minimally thermal energy source that exploits the biophysics of irreversible electroporation (IRE) to cause cell death. Differently from radiofrequ…
İrreversible
Mohamed et al · J Arrhythm
2025Sistematik Derleme / Meta-AnalizLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Pulmonary vein isolation is a standard therapy for paroxysmal atrial fibrillation (AF). Pulsed field ablation (PFA) has emerged as a novel approach aiming to improve efficacy and…
İrreversible
Prajapati et al · Pacing Clin Electrophysiol
2025Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: While radiofrequency ablation (RFA) and cryoablation (CBA) are established treatments for atrial fibrillation (AF), pulsed field ablation (PFA) offers potential benefits. This st…
İrreversible
Aldaas et al · J Interv Card Electrophysiol
2023Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulsed field ablation (PFA) induces cell death through electroporation using ultrarapid electrical pulses. We sought to compare the procedural efficiency characteristics, safety,…
İrreversible
O'Neill et al · J Surg Oncol
2020Sistematik Derleme / Meta-Analizİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground and objectives: Irreversible electroporation (IRE) is a nonthermal electrical tumor ablative strategy for unresectable tumors. IRE is relatively safe around critical structures bu…
İrreversible
Sugrue et al · J Interv Card Electrophysiol
2019Sistematik Derleme / Meta-AnalizHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuIntroduction: Irreversible electroporation (IRE) utilizing high voltage pulses is an emerging strategy for catheter-based cardiac ablation with considerable growth in the preclinical arena. …
İrreversible
Pürerfellner · Europace
2026Derlemeİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuPulsed field ablation (PFA) has rapidly evolved from an experimental electroporation-based concept to a widely adopted modality in cardiac electrophysiology, marking one of the fastest clini…
İrreversible
Eberl et al · J Cardiovasc Dev Dis
2025DerlemeLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuUnderstanding the biophysics of electroporation-the mechanism by which pulsed electric fields achieve tissue ablation-is essential for advancing this emerging technology. In this review, we …
İrreversible
Jacobs · Radiol Oncol
2025Derlemeİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground: Focal ablation techniques are integral in the surgical intervention of diseased tissue, where it is necessary to minimize damage to the surrounding parenchyma and critical struct…
İrreversible
Levy et al · Pacing Clin Electrophysiol
2025Derlemeİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuPulsed field ablation (PFA) is a cutting-edge treatment for arrhythmias that targets cardiac tissue with rapid, high-voltage electric current pulses, resulting in irreversible electroporatio…
İrreversible
Neven · Arrhythm Electrophysiol Rev
2025DerlemeLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuPulsed field ablation (PFA) represents a paradigm shift in the catheter-based treatment of AF, offering myocardial-selective ablation through the non-thermal mechanism of irreversible electr…
İrreversible
Ezzeddine et al · J Clin Med
2024DerlemeLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıOne of the recent advancements in the field of cardiac electrophysiology is pulsed field ablation (PFA). PFA is a novel energy modality that does not rely on thermal processes to achieve abl…
İrreversible
Guttipatti et al · Heart Surg Forum
2024DerlemeLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuPulsed field ablation (PFA) is a novel technology to treat atrial fibrillation (AF) utilizing electric fields to induce nonthermal irreversible electroporation of electrically active cardiac…
İrreversible
Di Monaco et al · J Cardiovasc Dev Dis
2022DerlemeLiteratür Analiziİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia and catheter ablation, which can be used in symptomatic patients refractory to antiarrhythmic therapy. Pulmonary vein…
İrreversible
Maan et al · Curr Cardiol Rep
2022Derlemeİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıPurpose of review: Current ablation approach for arrhythmias relies upon the use of radiofrequency (RF) and cryoablation catheters. Although there have been significant advances both in cath…
İrreversible
Bradley et al · J Cardiovasc Electrophysiol
2020Derlemeİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıPulsed-field ablation (PFA) is a promising new ablation modality for the treatment of atrial fibrillation. This energy form employs a train of microsecond duration high amplitude electrical …
İrreversible
Sugrue et al · Expert Rev Cardiovasc Ther
2018DerlemeHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre ÖlümüCardiac ablation is an established treatment modality for the management of patients with cardiac arrhythmias. Current approaches to cardiac ablation employ thermal based energy to achieve l…
İrreversible
Salameh et al · Ann Biomed Eng
2026Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Doku İletkenliği ve Empedans DeğişimiPurpose: Atherosclerotic vascular disease remains a leading cause of morbidity and mortality worldwide. Current treatments such as angioplasty, stenting, and atherectomy are invasive and lim…
İrreversible
Sowa et al · Bioelectrochemistry
2026Hayvan ÇalışmasıHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, Nanosaniye Darbeli Elektrik Alan (nsPEF)Achieving complete cardiac ablation requires higher electric fields, increasing the risk of vasospasm or collateral injury. A potential strategy to enhance ablation efficacy without raising …
İrreversible
Jacobs · Ann Biomed Eng
2025Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Doku İletkenliği ve Empedans DeğişimiPurpose: High-frequency irreversible electroporation (H-FIRE) is a pulsed field ablation (PFA) technique that employs a series of high-voltage, microseconds-long positive and negative pulses…
İrreversible
Ye et al · J Cardiovasc Electrophysiol
2025Hayvan ÇalışmasıHayvan (İn Vivo)Elektrik Alan Dağılımı ve Modellemesi, Reversible Membran PermeabilizasyonuBackground: Cardiomyocyte lines are widely used in cardiovascular research. For cardiac ablation, the factors affecting cardiomyocytes by pulsed electrical field (PEF) ablation are being inv…
İrreversible
Bhardwaj et al · Heart Rhythm
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Kas Kasılması ve Anestezi GereksinimiFocal delivery of microsecond pulsed field ablation (PFA) using small and large round/cylindrical tips have been described. Objective: To evaluate nanosecond (ns)PFA delivery using a novel f…
İrreversible
Di Biase et al · Circ Arrhythm Electrophysiol
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre ÖlümüBackground: The effect of contact force (CF) on lesion formation is not clear during pulsed field ablation (PFA). The aim of this study was to evaluate the impact of CF, PFA, and their inter…
İrreversible
Hua et al · Clin Cardiol
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Pulsed field ablation (PFA) has emerged as a novel non-thermal modality with highly myocardium-specific. However, the PFA catheter based on contact force (CF)-sensing has not bee…
İrreversible
Kocharian et al · Heart Rhythm
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre ÖlümüDespite the good safety profile of pulsed-filed energy (PF) for the ablation of atrial fibrillation (AF) reported in clinical studies, cases of renal failure caused probably by hemolysis wer…
İrreversible
Koruth et al · Heart Rhythm
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre ÖlümüPericardial adhesions develop in patients’ hearts after surgical cardiac intervention or infection. These adhesions make epicardial interventions such as ablation laborious. Advancing surgic…
İrreversible
Koya et al · J Cardiovasc Electrophysiol
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Kalsiyum Elektroporasyonu ve ATP TükenmesiIntroduction: Pulsed field ablation (PFA) has emerged as an innovative therapy for cardiac arrhythmias. Drawing parallels with PFA's application in solid tumors, calcium chloride (CaCl 2 ) a…
İrreversible
Nakagawa et al · Circ Arrhythm Electrophysiol
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Nekroz ve NekroptozBackground: During pulsed field ablation (PFA), relationships between ablation parameters (contact force [CF], number of burst pulses, impedance decrease, and electrode temperature) and lesi…
İrreversible
Nies et al · Circ Arrhythm Electrophysiol
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Kas Kasılması ve Anestezi GereksinimiBackground: Endocardial catheter-based pulsed field ablation (PFA) of the ventricular myocardium is promising. However, little is known about PFA's ability to target intracavitary structures…
İrreversible
Younis et al · JACC Clin Electrophysiol
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Doku İletkenliği ve Empedans DeğişimiBackground: Comparative efficacy and safety data on radiofrequency ablation (RFA) versus pulsed field ablation (PFA) for common idiopathic left ventricular arrhythmia (LV-VAs) locations are …
İrreversible
Younis et al · Circ Arrhythm Electrophysiol
2024Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Doku İletkenliği ve Empedans DeğişimiBackground: Conventional focal radiofrequency catheters may be modified to enable multiple energy modalities (radiofrequency or pulsed field [PF]) with the benefit of contact force (CF) feed…
İrreversible
Di Biase et al · Circ Arrhythm Electrophysiol
2023Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Pulsed field ablation (PFA) has emerged as an alternative to radiofrequency ablation. However, data on focal point-by-point PFA are scarce. The aim of this study was to compare l…
İrreversible
Gasperetti et al · Europace
2023Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuAims Pulsed field ablation (PFA) is a non-thermal ablative approach in which cardiomyocyte death is obtained through irreversible electroporation (IRE). Data correlating the biophysical char…
İrreversible
Mattison et al · J Cardiovasc Electrophysiol
2023Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre ÖlümüIntroduction: Contact force has been used to titrate lesion formation for radiofrequency ablation. Pulsed field ablation (PFA) is a field-based ablation technology for which limited evidence…
İrreversible
Howard et al · Circ Arrhythm Electrophysiol
2022Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Elektrik Alan Dağılımı ve ModellemesiBackground: Pulsed field ablation (PFA) is a novel energy modality for treatment of cardiac arrhythmias. The impact of electrode-tissue proximity on lesion formation by PFA has not been conc…
İrreversible
Li et al · BMC Cardiovasc Disord
2021Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground: High-Frequency Irreversible Electroporation (H-FIRE) is a novel technology for non-thermal ablation. Different from Irreversible electroporation (IRE), H-FIRE delivers bipolar el…
İrreversible
Koruth et al · Circ Arrhythm Electrophysiol
2020Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground: Pulsed field ablation (PFA) can be myocardium selective, potentially sparing the esophagus during left atrial ablation. In an in vivo porcine esophageal injury model, we compared…
İrreversible
Stewart et al · Heart Rhythm
2019Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Elektrot Geometrisi ve YerleşimiBackground: Radiofrequency (RF) has become an accepted energy source for myocardial ablation but may result in discontinuous lesions and nontargeted tissue injury. We examined the feasibilit…
İrreversible
van Es et al · Biomed Eng Online
2019Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground: Irreversible electroporation (IRE) using direct current (DC) is an effective method for the ablation of cardiac tissue. A major drawback of the use of DC-IRE, however, are two pr…
İrreversible
Jiang et al · Journal of Medical Devices
2013Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Darbe Parametrelerinin OptimizasyonuCardiovascular disease remains the number one cause of death in the United States, and in 2010 was responsible for 17% of the US health expenditures ($272.5 billion) [1]. Many acquired cardi…
İrreversible
Deodhar et al · AJR Am J Roentgenol
2011Hayvan ÇalışmasıHayvan (İn Vivo)Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre ÖlümüObjective: Irreversible electroporation is a nonthermal ablative tool that uses direct electrical pulses to create irreversible membrane pores and cell death. The ablation zone is surrounded…
İrreversible
Lavee et al · Heart Surg Forum
2007Hayvan ÇalışmasıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground: All currently used energy sources in surgical ablation for atrial fibrillation create lesions via thermal injury. We report for the first time the in vivo results of a new nonthe…
İrreversible
Zarębski et al · J Interv Card Electrophysiol
2026İn Vitro ÇalışmaHücre Kültürüİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuIntroduction: Pulsed field ablation (PFA) is a novel technique for pulmonary vein isolation (PVI) in the treatment of atrial fibrillation (AF). However, the impact of electrode type on lesio…
İrreversible
Herranz et al · –
2026Ön Baskıİrreversible Por Oluşumu ve Hücre Ölümü, Apoptoz İndüksiyonuPulsed field ablation (PFA) is increasingly used for atrial fibrillation, but the mechanisms of PFA-induced cell death remain incompletely understood. This study aimed to elucidate the early…
İrreversible
Jacobs et al · –
2026Ön BaskıHayvan (İn Vivo)Doku İletkenliği ve Empedans Değişimi, İrreversible Por Oluşumu ve Hücre ÖlümüObjective Pulsed field ablation (PFA) relies on irreversible electroporation to create nonthermal cardiac lesions, yet real-time indicators of electroporation progression and validated letha…
İrreversible
Li et al · –
2026Ön Baskıİrreversible Por Oluşumu ve Hücre Ölümü, Kas Kasılması ve Anestezi GereksinimiBackground Patients undergoing pulsed field ablation (PFA) for atrial fibrillation (AF) often have comorbid cardiovascular diseases and are highly sensitive to circulatory depression during …
İrreversible
Ullah et al · –
2026Ön Baskıİrreversible Por Oluşumu ve Hücre Ölümü, Sinir ve Damar Yapılarının KorunmasıBackground Three pulsed-field ablation (PFA) systems are FDA-approved for atrial fibrillation (AF), yet whether their safety profiles differ from each other and from radiofrequency (RF) abla…
İrreversible
Wan et al · –
2026Ön Baskıİrreversible Por Oluşumu ve Hücre ÖlümüPulsed field ablation (PFA)-guided pulmonary vein isolation (PVI) has limited efficacy in treating persistent atrial fibrillation (AF) and requires additional substrate modification, but the…
İrreversible
Wang et al · –
2026Ön Baskıİrreversible Por Oluşumu ve Hücre ÖlümüAims Pulsed field ablation (PFA) is a growing ablation modality for pulmonary vein isolation (PVI) in atrial fibrillation (AF) patients. This study assesses the 6-month safety and effectiven…
İrreversible
Salameh et al · –
2025Ön BaskıHayvan (İn Vivo)İrreversible Por Oluşumu ve Hücre Ölümü, Doku İletkenliği ve Empedans DeğişimiBackground Atherosclerotic vascular disease remains a leading cause of morbidity and mortality worldwide. Current treatments such as angioplasty, stenting, and atherectomy are invasive and l…
İrreversible
Campos-Villarreal et al · JACC Case Rep
2026Editöryal / Mektupİrreversible Por Oluşumu ve Hücre Ölümü[Figure: see text]
İrreversible
Nies et al · Circ Arrhythm Electrophysiol
2024Editöryal / Mektupİnsanİrreversible Por Oluşumu ve Hücre ÖlümüCirculation: Arrhythmia and Electrophysiology RESEARCH LETTER Hemolysis After Pulsed Field Ablation: Impact of Lesion Number and Catheter-Tissue Contact Moritz Nies , MD; Jacob S. Koruth , M…
İrreversible
Koruth et al · JACC Clin Electrophysiol
2022Editöryal / Mektupİnsanİrreversible Por Oluşumu ve Hücre Ölümücells from the mechanism of is esophageal contraction during atrial PFA, as well as ventricular contraction during annular or ventricular PFA. Catheter design, contact force, pulse waveform,…
İrreversible
Ha et al · J Interv Card Electrophysiol
2026Düzeltme / Erratumİrreversible Por Oluşumu ve Hücre Ölümür atrial fibrillation: tertiary centre experience and meta-analysis of observational studies Francis J. Ha1 · Sarah Paitry1 · Duron Prinsloo1 Emily Kotschet1 · Hui-Chen Han1 · Adam J Brown1 …
İrreversible
Krishan et al · Eur Heart J Open
2025Belirtilmemişİrreversible Por Oluşumu ve Hücre ÖlümüGraphical Abstract.
İrreversible
Lin et al · J Cardiovasc Electrophysiol
2025Protokolİnsanİrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran PermeabilizasyonuBackground: Pulsed field ablation (PFA) is gaining recognition as a nonthermal, tissue-specific technique for the treatment of atrial fibrillation (AF). The preclinical evaluation of the inv…
İrreversible
Reddy et al · Heart Rhythm O2
2023Protokolİrreversible Por Oluşumu ve Hücre ÖlümüBackground: Pulmonary vein isolation (PVI) is an effective treatment for paroxysmal atrial fibrillation (PAF). However, potential complications can occur due to the propagation of thermal en…

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