Baş ve Boyun Tümörleri
Baş-Boyun ve Orbita
Baş-boyun bölgesinde tümörler kritik anatomik yapılara komşudur ve tekrarlayan hastalıkta cerrahi ile radyoterapi seçenekleri sıklıkla tükenmiş olur. Elektrokemoterapi bu bağlamda palyatif lokal kontrol ve semptom kontrolü amacıyla değerlendirilir; mukozal yerleşimler ayrı bir teknik zorluk grubudur.
74toplam yayın
39klinik çalışma
8preklinik çalışma
15derleme
1998–2026yayın aralığı
Rejime Göre Kanıt Durumu
Reversible elektroporasyon (RE-ECT)
66yayın
35klinik
6preklinik
Klinik Kanıt
1998–2026 · Rutin Klinik Kullanımda
İrreversible elektroporasyon (IRE-ECT)
8yayın
4klinik
2preklinik
Erken Klinik Kanıt
2015–2026 · Klinik Kullanıma Yakın
Bu Alanda Raporlanan Mekanizmalar
Terimler, yayın özetleri üzerinde otomatik eşleştirmeyle saptanmıştır; rakam terimin geçtiği yayın sayısını gösterir.
Bleomisin Hücre İçi Birikiminin Artması 30
Reversible Membran Permeabilizasyonu 12
Kas Kasılması ve Anestezi Gereksinimi 9
İrreversible Por Oluşumu ve Hücre Ölümü 9
Nekroz ve Nekroptoz 7
Sisplatin Hücre İçi Birikiminin Artması 7
Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu 5
Elektrik Alan Dağılımı ve Modellemesi 5
Gen Elektrotransferi (Plazmid DNA) 4
Elektrot Geometrisi ve Yerleşimi 4
Sistemik / Abskopal İmmün Yanıt 4
Apoptoz İndüksiyonu 4
Çalışma Tipi Dağılımı
Çubuk uzunluğu en kalabalık çalışma tipine göre ölçeklenmiştir; yüzde ise alanın tamamındaki payı verir. Renk, çalışma tipinin kanıt basamağını gösterir; kanıt haritasındaki ile aynı ölçek.
| Çalışma tipi | Yayın | Bu alandaki payı |
|---|---|---|
| Randomize Klinik Çalışma | 2 | %3 |
| Prospektif Klinik Çalışma | 4 | %5 |
| Klinik Çalışma | 27 | %36 |
| Retrospektif Klinik Çalışma | 3 | %4 |
| Vaka Serisi | 3 | %4 |
| Vaka Raporu | 11 | %15 |
| Sistematik Derleme / Meta-Analiz | 4 | %5 |
| Derleme | 11 | %15 |
| Hayvan Çalışması | 7 | %9 |
| İn Siliko / Modelleme | 1 | %1 |
| Editöryal / Mektup | 1 | %1 |
Literatür Kanıt Tablosu
74 yayın, kanıt gücü sırasına göre listelenmiştir. Başlığa tıklayarak künye, mekanizma ve tam özet çekmecesini açabilirsiniz.
| Rejim | Yayın | Yıl | Çalışma tipi | Model | Mekanizma | Özet |
|---|---|---|---|---|---|---|
| Reversible | Perri et al · Cancers (Basel) | 2021 | Randomize Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, İmmün Kontrol Noktası İnhibitörü Kombinasyonu | Background: A significant proportion of patients with head and neck squamous cell carcinoma (HNSCC) have advanced-stage disease (stages III to IVB) that do not respond to therapy despite agg… |
| Reversible | Plaschke et al · Laryngoscope Investig Otolaryngol | 2019 | Randomize Klinik Çalışma | İnsan | Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Nekroz ve Nekroptoz | Background: Calcium electroporation is a novel cancer treatment, which combines temporary cell permeability from electroporation with a high influx of calcium intracellularly resulting in ca… |
| İrreversible | Khudayberganov · – | 2024 | Prospektif Klinik Çalışma | İnsan | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | Irreversible electroporation (IRE) is a novel non-thermal tissue ablation technology. The objective of this study was to evaluate the safety and efficacy of IRE in the treatment of adenotons… |
| Reversible | Al-Hadithy et al · Int J Surg | 2018 | Prospektif Klinik Çalışma | İnsan | – | Metastatic spread of malignant tumours to skin is a well described phenomenon with incidence of approximately 0.7-9% of all metastases depending on histological type of primary cancer. Elect… |
| Reversible | Bertino et al · Eur J Cancer | 2016 | Prospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | Electrochemotherapy is an effective and safe method for local treatment of cutaneous and subcutaneous tumours, where electric pulses cause increased permeability of cell membranes in the tum… |
| Reversible | Bertino et al · http://isrctn.com/ | 2015 | Prospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | Electrochemotherapy is an effective and safe method for local treatment of cutaneous and subcutaneous tumours, where electric pulses cause increased permeability of cell membranes in the tum… |
| İrreversible | Li et al · J Clin Endocrinol Metab | 2026 | Klinik Çalışma | İnsan | Nanosaniye Darbeli Elektrik Alan (nsPEF), Reversible Membran Permeabilizasyonu | Context Nanosecond pulsed electric field (nsPEF) ablation has gradually been applied in clinical practice. However, no studies have reported its application in low-risk papillary thyroid mic… |
| Reversible | Latini et al · J Clin Med | 2025 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Elektrik Alan Dağılımı ve Modellemesi | Background : According to the ISSVA 2018 classification, arteriovenous malformations (AVMs) are high-flow vascular malformations, distinct from low-flow lesions. About 60% of extracranial AV… |
| Reversible | Bertino et al · Eur J Surg Oncol | 2024 | Klinik Çalışma | İnsan | – | The aim of this multicenter study was to evaluate the effectiveness and safety of electrochemotherapy (ECT) for the treatment of mucosal tumors in the head and neck. A total of 71 patients w… |
| Reversible | Barca et al · Oral and Maxillofacial Surgery Cases | 2023 | Klinik Çalışma | İnsan | – | Treatment of advanced-stage head and neck cutaneous squamous cell carcinoma is a challenge for maxillofacial surgeons, oncologists, and radiotherapists. These carcinomas respond with difficu… |
| Reversible | Groselj · Radiol Oncol | 2022 | Klinik Çalışma | İnsan | İnterlökin-12 Aracılı İmmün Uyarım, Gen Elektrotransferi (Plazmid DNA) | Background: Immune therapies are currently under intensive investigation providing in many cases excellent responses in different tumors. Other possible approach for immunotherapy is a targe… |
| Reversible | Krt et al · Front Oncol | 2022 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | Introduction: The study aims to demonstrate a combination of superselective catheterization and electrochemotherapy as a feasible and effective new technological approach in treating high-fl… |
| Reversible | Maglitto et al · Eur Rev Med Pharmacol Sci | 2022 | Klinik Çalışma | İnsan | – | Objective: The aim of this study was to identify features mainly involved in determining the partial response (PR) to the Electrochemotherapy (ECT) in patients with recurrent and/or metastat… |
| Reversible | Wolff et al · Biomedicines | 2022 | Klinik Çalışma | İnsan | Mitokondriyal Disfonksiyon ve Oksidatif Stres, İmmünojenik Hücre Ölümü (ICD) | In modern oncology, therapies are based on combining monotherapies to overcome treatment resistance and increase therapy precision. The application of microsecond-pulsed electric fields (PEF… |
| Reversible | Condello et al · Cancers (Basel) | 2021 | Klinik Çalışma | İnsan | Apoptoz İndüksiyonu, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | We investigated the chemosensitizing effect of electroporation (EP), which, using electrical pulses, permeabilizes cancer cells to drugs. The study involved two human hypopharyngeal and tong… |
| Reversible | Riva et al · J Clin Med | 2021 | Klinik Çalışma | İnsan | Hemostaz ve Kanama Kontrolü | Background: Primary or recurrent head and neck cancer of skin or mucosa represents a challenge for clinicians and could be debilitating for the patient. Electrochemotherapy (ECT) emerged as … |
| Reversible | Zimmermann et al · Acta Otolaryngol | 2021 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Hemostaz ve Kanama Kontrolü | Background: The role of electrochemotherapy (ECT) using intratumoral bleomycin and electroporation as a first line treatment for oral tongue carcinoma has not been defined. Aims/objectives: … |
| Reversible | Longo et al · Cancers (Basel) | 2020 | Klinik Çalışma | İnsan | – | Head and neck squamous cell carcinomas (SCCHN) are not rare malignancies and account for 7% of all solid tumors. Prognosis of SCCHN patients strongly depends on tumor extension, site of onse… |
| Reversible | Bonadies et al · Acta Derm Venereol | 2019 | Klinik Çalışma | İnsan | – | Skin malignancies of the head and neck inflict significant structural, functional, and cosmetic burdens upon those affected. We retrospectively addressed electrochemotherapy anti-tumour effi… |
| Reversible | Longo et al · Oral Oncol | 2019 | Klinik Çalışma | İnsan | – | Purpose: To describe outcomes of Electrochemotherapy as palliative treatment in patients with advanced head and neck (H&N) tumours. Methods: Ninety-three patients (120 treatment sessions) wi… |
| Reversible | Zakelj et al · Oncol Rep | 2019 | Klinik Çalışma | İnsan | Sisplatin Hücre İçi Birikiminin Artması, Bleomisin Hücre İçi Birikiminin Artması | Electrochemotherapy is an established local ablative method used for the treatment of different tumor types, including tumors of the head and neck area. Clinical studies have demonstrated a … |
| Reversible | Pichi et al · Acta Otorhinolaryngol Ital | 2018 | Klinik Çalışma | İnsan | – | Electrochemotherapy (ECT) is a well established treatment strategy for skin tumuors. The aim of this study was to evaluate the feasibility and efficacy of electrochemotherapy in the palliati… |
| Reversible | Plaschke et al · Head Neck | 2018 | Klinik Çalışma | İnsan | Kas Kasılması ve Anestezi Gereksinimi | Background: Electrochemotherapy is an established treatment for cutaneous tumors. This study aimed at determining efficacy of electrochemotherapy in recurrent head and neck cancer. Methods: … |
| Reversible | Plaschke et al · Eur J Cancer | 2017 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | Aim: Electrochemotherapy is an effective local treatment for cutaneous tumours and metastases. In this prospective trial, six European institutions investigated electrochemotherapy in recurr… |
| Reversible | Landström et al · Acta Otolaryngol | 2015 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | Conclusion: ECT can be a safe curative mono modality treatment, especially in tongue cancer. The future role for ECT in head and neck cancer needs to be further investigated. Introduction: E… |
| Reversible | Campana et al · Eur J Surg Oncol | 2014 | Klinik Çalışma | İnsan | – | Electrochemotherapy (ECT) holds promise as a minimally invasive palliative tool for selected patients with peristomal tumors. We present the favorable short-term outcome of three patients (t… |
| Reversible | Landström et al · Acta Otolaryngol | 2014 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Sistemik / Abskopal İmmün Yanıt | Conclusion: Electrochemotherapy (ECT) is an efficacious treatment. It should, however, be used with some caution in the treatment of head and neck cancer. Objectives: To assess local tumor c… |
| Reversible | Rossi et al · European Journal of Surgical Oncology (EJSO) | 2013 | Klinik Çalışma | İnsan | – | S56 2 Universita Insubria, Varese, Italy University Catholique de Louvian, Bruxelles, Italy * Corresponding author. Bellini Maria Irene ,Tor Vergata University, Roma, Italy. E-mail address:… |
| Reversible | Gargiulo et al · Ann Surg | 2012 | Klinik Çalışma | İnsan | Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu, Kas Kasılması ve Anestezi Gereksinimi | Objective: To evaluate and confirm the efficacy and safety of electrochemotherapy (ECT) using bleomicyn in a large series of non-melanoma head and neck cancers. Background: ECT combines chem… |
| Reversible | Grau et al · Annals of Oncology | 2012 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | ECT is the administration of electrical pulses in the tumour during perfusion of chemotherapy allowing the introduction of the drug in neoplastic cell. H&N regional relapse no suitable for l… |
| Reversible | Mevio et al · Tumori | 2012 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Reversible Membran Permeabilizasyonu | Aims and background: Electrochemotherapy is a tumor ablation modality providing delivery into the cell interior of impermeant or poorly permeant chemotherapeutic drugs such as cisplatin and … |
| Reversible | Gargiulo et al · Annals of Surgery | 2010 | Klinik Çalışma | İnsan | – | e read with great interest the article entitled, “Electrochemotherapy: Aspects of Preclinical Development and Early Clinical Experience” published in your esteemed journal in March 2007.1 An… |
| Reversible | Landström et al · Acta Otolaryngol | 2010 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | Conclusion: Electroporation therapy appears to be a safe treatment achieving excellent local tumor control and very good functional results in our study and it should be further clinically e… |
| Reversible | Vielsmeier et al · Biomedicines | 2025 | Retrospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | Background/Objectives: Bleomycin electrosclerotherapy (BEST), which combines intralesional bleomycin administration with electroporation, enhances drug uptake and has shown efficacy in treat… |
| Reversible | Barca et al · Int J Environ Res Public Health | 2023 | Retrospektif Klinik Çalışma | İnsan | – | Advanced oral squamous cell carcinomas represent a major challenge for maxillofacial surgeons, oncologists and radiation therapists. They also account for a large share of healthcare costs. … |
| Reversible | Campana et al · Br J Oral Maxillofac Surg | 2014 | Retrospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | Electrochemotherapy increases the permeability of tumours to drugs by electric voltages applied locally. Its value in tumours of the head and neck is unknown. We retrospectively reviewed a 2… |
| İrreversible | Khasanov et al · J Clin Med | 2026 | Vaka Serisi | İnsan | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | Background/Objectives: Irreversible electroporation (IRE) is a non-thermal tissue ablation technology, offering potential advantages such as reductions in pain, bleeding, and procedural time… |
| İrreversible | Sarafoleanu et al · Otolaryngol Head Neck Surg | 2026 | Vaka Serisi | İnsan | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | Objective: To evaluate the safety and efficacy of irreversible electroporation for non-thermal ablation of tonsils in adults. Study design: Prospective interventional case series of 24 adult… |
| Reversible | Sampate et al · IJARS | 2025 | Vaka Serisi | İnsan | – | Introduction: Head and Neck Carcinomas (HNC) are a significant cancer burden in India and worldwide, often necessitating palliative care due to their locoregional relapse. Electrochemotherap… |
| Reversible | Chiari et al · J Stomatol Oral Maxillofac Surg | 2026 | Vaka Raporu | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Nekroz ve Nekroptoz | Background: Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm arising from follicular dendritic cells, with a predilection for extranodal sites. FDCS of the tonsil is exceptionally… |
| Reversible | Bonadies et al · Biomedicines | 2023 | Vaka Raporu | İnsan | Bleomisin Hücre İçi Birikiminin Artması | Background: Brooke-Spiegler syndrome is a rare autosomal dominant disorder characterized by the continuous development of multiple benign skin appendage tumors. It is treated usually by repe… |
| İrreversible | Xu et al · QJM | 2022 | Vaka Raporu | İnsan | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | Irreversible electroporation (IRE) is a novel non-thermal ablation modality and has unique advantages for the treatment of tumors adjacent to vital structures. Our case highlights that IRE m… |
| Reversible | Landström et al · Anticancer Res | 2021 | Vaka Raporu | İnsan | Bleomisin Hücre İçi Birikiminin Artması | Background/aim: Electrochemotherapy (ECT) is a cancer treatment modality where the efficacy of a chemotherapeutic agent is enhanced by an electrical field. It is an established palliative tr… |
| Reversible | Pichi et al · JAMA Otolaryngol Head Neck Surg | 2020 | Vaka Raporu | İnsan | – | Response to Electrochemotherapy in a Patient With Advanced Oropharyngeal Squamous Cell Carcinoma Figure 1. Axial T1 With Gadolinium Sequence Magnetic Resonance Imaging Showing an Infiltrativ… |
| Reversible | Salehi et al · Vet Res Forum | 2018 | Vaka Raporu | İnsan | Bleomisin Hücre İçi Birikiminin Artması | A five-year-old female African hedgehog ( Atelerix albiventris ) was referred for a one month growing oral mass. The hedgehog was quiet, alert and responsive, with a 1.00 × 1.50 cm ulcerated… |
| Reversible | Vitfell-Rasmussen et al · Acta Oncol | 2017 | Vaka Raporu | İnsan | – | Aggressive fibromatosis also known as desmoid tumors constitute 3% of soft tissue tumors and 0.03% of all cancers [1]. They most commonly occur in women after childbirth and the gender ratio… |
| Reversible | Groselj et al · Biomed Eng Online | 2015 | Vaka Raporu | İnsan | Elektrot Geometrisi ve Yerleşimi, Elektrik Alan Dağılımı ve Modellemesi | Background: Electrochemotherapy provides highly effective local treatment for a variety of tumors. In deep-seated tumors of the head and neck, due to complex anatomy of the region or inabili… |
| Reversible | Holdsworth et al · JPRAS Open | 2015 | Vaka Raporu | İnsan | – | A 65-year-old man presented with an uncontrolled Merkel cell carcinoma on his chest that originated from his forearm. He previously had an amputation at the shoulder joint, but his disease r… |
| İrreversible | Meijerink et al · J Vasc Interv Radiol | 2015 | Vaka Raporu | İnsan | Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü | A 74-year-old man presented with a small locoregional, histopathologically proven, fluorodeoxyglucose positron emission tomography/computed tomography-avid recurrence of follicular thyroid c… |
| Reversible | Panje et al · Am J Rhinol | 2000 | Vaka Raporu | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Reversible Membran Permeabilizasyonu | The purpose of this article is to introduce the concept of endoscopic and electroporation therapy for the treatment of sinonasal carcinomas. Electroporation therapy is a technique that combi… |
| Reversible | Chiari et al · Eur Arch Otorhinolaryngol | 2025 | Sistematik Derleme / Meta-Analiz | İnsan | Sistemik / Abskopal İmmün Yanıt | Objective: The primary objective of this review is to assess the survival outcomes of patients affected by oral cavity and oropharyngeal squamous cell carcinoma (SCC) treated with electroche… |
| Reversible | Jiménez-Labaig et al · Cancer Treat Rev | 2024 | Sistematik Derleme / Meta-Analiz | İnsan | Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Hemostaz ve Kanama Kontrolü | Background: Head and neck squamous cell carcinoma (HNSCC) presents an ideal scenario for intratumoral therapies (IT), due to its local recurrence pattern and frequent superficial extension. … |
| Reversible | Lenzi et al · Eur Arch Otorhinolaryngol | 2017 | Sistematik Derleme / Meta-Analiz | İnsan | Nekroz ve Nekroptoz | Electroporation, also known as electrochemotherapy, combines an antineoplastic agent with electroporation, causing localized progressive necrosis in the treated area. Today it is primarily u… |
| Reversible | Plaschke et al · Acta Oncol | 2016 | Sistematik Derleme / Meta-Analiz | İnsan | – | Background: Electrochemotherapy, the combination of electroporation and chemotherapy, is mainly used in the palliative setting for treatment of cutaneous and subcutaneous metastases; however… |
| Reversible | Mahendra Prabu · – | 2026 | Derleme | Literatür Analizi | Reversible Membran Permeabilizasyonu, Bleomisin Hücre İçi Birikiminin Artması | Background: Head and Neck Cancer (HNC) is still considered a major global health problem because it usually presents itself with a high incidence of recurrence and associated disabilities [1… |
| Reversible | Cariti et al · Acta Otorhinolaryngol Ital | 2024 | Derleme | İnsan | – | Head and neck cancers are mostly represented by squamous cell carcinoma. Despite effective treatment of primary tumours, local recurrences and metastases are frequent, with up to a 60% risk … |
| Reversible | Morozas et al · Front Oncol | 2024 | Derleme | Literatür Analizi | Elektrik Alan Dağılımı ve Modellemesi, Bleomisin Hücre İçi Birikiminin Artması | Head and neck cancer continues to be among the most prevalent types of cancer globally, yet it can be managed with appropriate treatment approaches. Presently, chemotherapy and radiotherapy … |
| Reversible | Pisani et al · Cancers (Basel) | 2022 | Derleme | Literatür Analizi | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | Squamous cell carcinoma is the most common malignancy that arises in the head-and-neck district. Traditional treatment could be insufficient in case of recurrent and/or metastatic cancers; f… |
| Reversible | Enokida et al · Cancers (Basel) | 2021 | Derleme | Literatür Analizi | İmmün Kontrol Noktası İnhibitörü Kombinasyonu | Despite recent advances in the development of chemotherapeutic drug, treatment for advanced cancer of the head and neck cancer (HNC) is still challenging. Options are limited by multiple fac… |
| Reversible | de Bree et al · Curr Opin Otolaryngol Head Neck Surg | 2020 | Derleme | İnsan | Bleomisin Hücre İçi Birikiminin Artması | Purpose of review: Electrochemotherapy (ECT) is increasingly used in different settings in head and neck cancer patients when conventional treatment options are not available. Recent finding… |
| Reversible | De Virgilio et al · Oncol Lett | 2018 | Derleme | Literatür Analizi | – | Patients affected by aggressive neoplasms with a high propensity to metastasize to the skin, including some types of head and neck cancer, may benefit from electrochemotherapy, a modality th… |
| Reversible | Benazzo et al · Handbook of Electroporation | 2017 | Derleme | Literatür Analizi | Elektrot Geometrisi ve Yerleşimi, Bleomisin Hücre İçi Birikiminin Artması | In the head and neck area, electrochemotherapy (ECT) is currently implemented for the treatment of recurrent and/or metastatic cutaneous, subcutaneous, mucosal, or deep-seated tumors of any … |
| Reversible | Ribero et al · Radiol Oncol | 2016 | Derleme | Literatür Analizi | – | Background: Metastatic extraorbital sebaceous carcinoma is a rare event that could involve the head and neck. The treatment of choice for the initial stage of the disease is surgery and/or r… |
| Reversible | Landström FJ · – | 2015 | Derleme | Literatür Analizi | Bleomisin Hücre İçi Birikiminin Artması, Antivasküler Etki ve Damar Yıkımı | Fredrik Landström (2015): Curative Electrochemotherapy in the Head and Neck Area. Örebro Studies in Medicine 117. Electrochemotherapy (ECT) is a local cancer treatment modality in which the … |
| Reversible | Soni · Ecancermedicalscience | 2015 | Derleme | Literatür Analizi | – | Hidradenocarcinoma is a rare malignant adnexal tumour which arises from the intradermal duct of eccrine sweat glands. The head and neck are the most common sites of hidradenocarcinoma, but r… |
| İrreversible | Tao et al · Acta Otolaryngol | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | Background: Irreversible electroporation (IRE)/nanoknife is a nonthermal technique for ablating solid tumors. Objectives: To investigate the application of IRE for ablating tonsil tissues in… |
| İrreversible | Lv et al · Technol Cancer Res Treat | 2019 | Hayvan Çalışması | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü | Background: Nonthermal irreversible electroporation is a minimally invasive surgery technology that employs high and brief electric fields to ablate undesirable tissues. Nonthermal irreversi… |
| Reversible | Quaglino et al · Cancers (Basel) | 2011 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | DNA vaccination exploits a relatively simple and flexible technique to generate an immune response against microbial and tumor-associated antigens (TAAs). Its effectiveness is enhanced by th… |
| Reversible | Fujimoto et al · J Int Med Res | 2005 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | The aim of this study was to determine the effects of low-voltage electrochemotherapy with intraperitoneal cisplatin on hamster oral fibrosarcoma. Oral fibrosarcoma was transplanted submucos… |
| Reversible | Omura et al · International Journal of Oral and Maxillofacial Surgery | 2000 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Nekroz ve Nekroptoz | This study evaluated the effects of electrochemotherapy (ECT) with intratumoral injection of bleomycin (BLM) on the chemically induced tongue cancer model in the hamster. Intratumoral inject… |
| Reversible | Omura et al · J Oral Maxillofac Surg | 1999 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | Purpose: This study investigated the in vivo antitumor effects of electrochemotherapy (ECT) using electroporation and bleomycin in a hamster tongue cancer model to assess its clinical applic… |
| Reversible | Hasegawa et al · J Oral Pathol Med | 1998 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması | Electrochemotherapy (ECT) is a new technique that enhances the antitumor effect of various anticancer agents by delivering high-voltage electrical impulses to the tumor. A rat squamous cell … |
| Reversible | Lopes et al · IEEE Trans. Instrum. Meas. | 2026 | İn Siliko / Modelleme | Hesaplamalı Model | Doku İletkenliği ve Empedans Değişimi, Elektrik Alan Dağılımı ve Modellemesi | Electroporation (EP)–based cancer therapies, such as electrochemotherapy (ECT) and irreversible electroporation (IRE), require accurate characterization of tissue electrical properties to pr… |
| Reversible | De Virgilio et al · Tumori | 2013 | Editöryal / Mektup | İnsan | – | We would like to take the opportunity to comment on the paper by Mevio et al.1 in the May-June 2012 issue of Tumori titled “Electrochemotherapy for the treatment of recurrent head and neck c… |
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