Grup: Derin Organ Tümörleri
Meme Kanseri
Meme kanserinin göğüs duvarı nüksleri ve deri metastazları, korpusta elektrokemoterapi için en çok yayın bulunan endikasyonlar arasındadır. Bu lezyonlar sıklıkla ışınlanmış dokuda gelişir, kanamalı ve kokulu olabilir; lokal kontrol, kanama kontrolü ve yaşam kalitesi bu literatürde değerlendirilen klinik sonuçlar arasındadır.
Klinik yayın: randomize, prospektif ve retrospektif çalışma, vaka serisi ve vaka raporu. Preklinik yayın: hayvan, in vitro, modelleme ve deneysel biyofizik çalışmaları.
Yayınların Bildirdiği Klinik ve Teknik Veriler
Bu alandaki 120 yayının 119 tanesinde tam metinde bildirilen alanların toplamı. Sayılar toplanır, yorumlanmaz.
Toplamlar benzersiz hasta sayısı değildir: aynı kohort birden fazla yayında raporlanmış olabilir.
Yönteme Göre Literatür Durumu
Klinik yöntem başına yayın sayısı, klinik ve preklinik dağılım, literatür hacmi ve yayın aralığı. Sayfa girişindeki rozet yalnızca ECT kaydını özetler; yöntem ayrımının tamamı buradadır.
Elektrokemoterapi (ECT)
Sınırlı klinik yayın hacmieşik 10/87 kayıt
Bu sayının klinik ve preklinik dağılımı: klinik 6, preklinik 1.
1991–2026
İrreversible elektroporasyon (IRE)
Keşifsel / düşük hacimli literatüreşik 1/8 kayıt
Bu sayının klinik ve preklinik dağılımı: klinik 0, preklinik 1.
2009–2022
Kalsiyum elektroporasyonu
Keşifsel / düşük hacimli literatüreşik 0/3 kayıt
Bu yöntemin hiçbir kaydı hacim etiketine girmemiştir.
2019–2025
Gen elektrotransferi
Keşifsel / düşük hacimli literatüreşik 0/7 kayıt
Bu yöntemin hiçbir kaydı hacim etiketine girmemiştir.
2007–2020
Diğer elektroporasyon uygulamaları
Bu küme tek bir klinik yöntemi adlandırmaz; literatür hacmi atanmaz.
2000–2026
Özetlerde Anılan Mekanizmalar
Rakam, mekanizma adının geçtiği özet sayısıdır. Bir mekanizmanın anılması, o çalışmada gösterildiği anlamına gelmez.
Çalışma Tipi Dağılımı
Yüzde, alanın tamamındaki payı verir.
| Çalışma tipi | Yayın | Bu alandaki payı |
|---|---|---|
| Randomize Klinik Çalışma | 1 | <%1 |
| Prospektif Klinik Çalışma | 6 | %5 |
| Klinik Çalışma | 25 | %21 |
| Retrospektif Klinik Çalışma | 4 | %3 |
| Vaka Serisi | 1 | <%1 |
| Vaka Raporu | 12 | %10 |
| Sistematik Derleme / Meta-Analiz | 1 | <%1 |
| Derleme | 7 | %6 |
| Hayvan Çalışması | 23 | %19 |
| İn Vitro Çalışma | 29 | %24 |
| İn Siliko / Modelleme | 1 | <%1 |
| Editöryal / Mektup | 3 | %2 |
| Düzeltme / Erratum | 3 | %2 |
| Belirtilmemiş | 3 | %2 |
| Protokol | 1 | <%1 |
Yayın Tablosu
120 yayın kaydı, çalışma tasarımına göre sıralanmıştır. Başlığa tıklayarak künye, mekanizma ve tam özet çekmecesini açabilirsiniz.
Sınıflandırmalar otomatik üretilir ve tekil kayıtlarda hata içerebilir. Metodoloji
| Rejim | Yayın | Yıl | Çalışma tipi | Model | Mekanizma | Hasta / lezyon | Cihaz | Ajan ve yol | Bildirilen sonuç | Özet |
|---|---|---|---|---|---|---|---|---|---|---|
| ECT | Tahvildari et al · Int J Cancer Manag | 2025 | Randomize Klinik Çalışma | İnsan | Kas Kasılması ve Anestezi Gereksinimi, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | 64 | – | bleomisin · hem intravenöz hem intratümöral | – | Background: Skin metastases occur in 5% - 30% of breast cancer patients, highlighting the need for effective treatments. Electrochemotherapy, which combines electric pulses with chemotherapy… |
| ECT | Russano et al · Clin Exp Metastasis | 2025 | Prospektif Klinik Çalışma | İnsan | Sistemik / Abskopal İmmün Yanıt | 195 / 593 | – | bleomisin · hem intravenöz hem intratümöral | nesnel yanıt 82% (195 hasta) | Electrochemotherapy (ECT) is a local treatment combining chemotherapy with electroporation. This prospective multicentre study aimed to evaluate the efficacy of ECT in the treatment of patie… |
| Diğer EP | Aigner et al · European Journal of Surgical Oncology | 2023 | Prospektif Klinik Çalışma | İnsan | Reversible Membran Permeabilizasyonu, Bleomisin Hücre İçi Birikiminin Artması | 11 | – | bleomisin · intraarteryel | – | Relapsed unresectable triple negative breast cancer is a demanding disease with currently no standard treatment option. Especially for patients with huge tumor masses a treatment that offers… |
| ECT | Matthiessen et al · Clin Breast Cancer | 2018 | Prospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Kas Kasılması ve Anestezi Gereksinimi | 119 / 244 | – | bleomisin · hem intravenöz hem intratümöral | tam yanıt 50% (90 hasta) | Background: Cutaneous recurrence from breast cancer can pose a clinical challenge. It might be the only disease site, or could be part of disseminated disease, and often profoundly affects q… |
| ECT | Matthiessen et al · Annals of Oncology | 2016 | Prospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Kas Kasılması ve Anestezi Gereksinimi | 104 | IGEA electroporation system | bleomisin · hem intravenöz hem intratümöral | tam yanıt 51% (75 hasta) | Cutaneous recurrence from breast cancer can pose a clinical challenge. It may be the only disease site, or be part of disseminated disease, and often profoundly impacts quality of life. Elec… |
| ECT | Benevento et al · Int J Surg Case Rep | 2015 | Prospektif Klinik Çalışma | İnsan | – | 1 / 51 | IGEA square wave electroporator | bleomisin · intravenöz | tam yanıt 100% (51 lezyon) | Introduction: Angiosarcomas are highly malignant endothelial cell tumors with poor prognosis. These can be due to breast cancer itself or to subsequent therapeutic modalities. No evidence-ba… |
| ECT | Cabula · European Journal of Surgical Oncology (EJSO) | 2013 | Prospektif Klinik Çalışma | İnsan | – | 5 | – | bleomisin | lokal nüks 0 adet (5 hasta) | C. Cabula* Ospedale Oncologico, Cagliari, Italy * Corresponding author. Cabula C. Cagliari, Italy. E-mail address: carlocabula@oncologiachirurgica.it. ABSTRACTS 5 patients with breast cancer… |
| Diğer EP | Aigner et al · Cancers (Basel) | 2024 | Klinik Çalışma | İnsan | Reversible Membran Permeabilizasyonu, Bleomisin Hücre İçi Birikiminin Artması | 14 | Cliniporator | sisplatin · intraarteryel | tam yanıt 2 adet (14 hasta) | Background: Relapsed unresectable triple-negative breast cancer is a demanding disease with only a few treatment options. Especially for patients with unresectable tumor masses, a treatment … |
| Diğer EP | Bieżuńska-Kusiak et al · Pharmaceuticals (Basel) | 2023 | Klinik Çalışma | İnsan | – | – | BTX ECM830 | kalsiyum klorür | – | Breast cancer ranks among the top three most common malignant neoplasms in Poland. The use of calcium ion-assisted electroporation is an alternative approach to the classic treatment of this… |
| ECT | Di Prata et al · Cancers (Basel) | 2023 | Klinik Çalışma | İnsan | – | 171 | Cliniporator | bleomisin · intravenöz | tam yanıt 49% (171 hasta) | Electrochemotherapy has been proven to be an efficient treatment for cutaneous metastases of various cancers. Data on breast cancer (BC) patients with cutaneous metastases were retrieved fro… |
| ECT | Bartolo et al · The Breast | 2019 | Klinik Çalışma | İnsan | – | 30 | – | bleomisin · intravenöz | genel sağkalım 100% (30 hasta) | Surgery of the primary tumor and the axilla is a mandatory part of the treatment in early breast cancer (BC). In the metastatic setting, surgery may be discussed as a procedure, improving lo… |
| ECT | Wichtowski et al · Oncol Res Treat | 2018 | Klinik Çalışma | İnsan | – | 38 | Cliniporator | bleomisin · intravenöz | tam yanıt 42% (38 hasta) | Introduction: Breast cancer is responsible for more than 50% of cutaneous metastases. One of the treatment options is electrochemotherapy (ECT). It is an effective method of local tumor abla… |
| ECT | Grischke et al · Radiol Oncol | 2017 | Klinik Çalışma | İnsan | Nekroz ve Nekroptoz | 33 | Cliniporator | bleomisin · intravenöz | nesnel yanıt 90% | Background: Electrochemotherapy (ECT) is an established procedure for treating breast cancer loco-regional recurrences following surgical intervention and/or radiotherapy. Limited informatio… |
| ECT | Guida et al · Annals of Oncology | 2017 | Klinik Çalışma | İnsan | – | 125 / 214 | – | bleomisin | tam yanıt 58.4% (113 hasta) | Bu yayında özet bulunmuyor. |
| ECT | Bourke et al · Breast Cancer Res Treat | 2016 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | – | Cliniporator | bleomisin · intravenöz | – | Purpose: Electrochemotherapy (ECT) is the application of electric pulses to tumour tissue to render the cell membranes permeable to usually impermeant hydrophilic anti-cancer drugs, thereby … |
| ECT | Piechocki et al · Curr. Gynecol. Oncol. | 2016 | Klinik Çalışma | İnsan | Hemostaz ve Kanama Kontrolü | 13 | Cliniporator | bleomisin · intravenöz | tam yanıt 1 adet (13 hasta) | Electrochemotherapy is a local therapy method reserved for cases not subject to surgery in advanced surface-localized cancers in the integuments. It may be applied in treating primary skin n… |
| ECT | Denzi et al · Biomed Eng Online | 2015 | Klinik Çalışma | İnsan | Nekroz ve Nekroptoz, Elektrot Geometrisi ve Yerleşimi | 1 / 1 | Cliniporator VITAE | bleomisin · intravenöz | – | Background: Breast cancer is the most common cancer in women worldwide and is the second most common cause of cancer death in women. Electrochemotherapy (ECT) used in early-phase clinical tr… |
| ECT | Kalavathy et al · JCPCR | 2015 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | 2 | – | bleomisin · hem intravenöz hem intratümöral | nesnel yanıt 90% (1 hasta) | Electrochemotherapy (ECT) is a local cancer treatment modality where the intracellular accumulation of a chemotherapeutic agent is enhanced in the presence of an electrical field by the phen… |
| ECT | Mercantini et al · The American Surgeon™ | 2015 | Klinik Çalışma | İnsan | – | 2 | Cliniporator | bleomisin · intravenöz | tam yanıt 100% (2 hasta) | Bu yayında özet bulunmuyor. |
| ECT | Sundararajan · JCPCR | 2015 | Klinik Çalışma | İnsan | Sisplatin Hücre İçi Birikiminin Artması, Bleomisin Hücre İçi Birikiminin Artması | – | BTX ECM830 | diğer | hücre canlılığı 44% | Triple negative breast cancer (TNBC) has poor prognosis. This is due to lack of estrogen, progesterone and HER-2 receptors. About 15% of all breast cancers are TNBC. This year in the US alon… |
| ECT | Wichmann Matthiessen et al · Radiol Oncol | 2013 | Klinik Çalışma | İnsan | – | 11 / 16 | – | bleomisin · intravenöz | nesnel yanıt 31% (16 lezyon) | Background: Electrochemotherapy is a local anticancer treatment very efficient for treatment of small cutaneous metastases. The method is now being investigated for large cutaneous recurrenc… |
| ECT | Campana et al · European Journal of Surgical Oncology (EJSO) | 2013 | Klinik Çalışma | İnsan | – | 60 / 242 | – | – | tam yanıt 36.7% (60 hasta) | Bu yayında özet bulunmuyor. |
| ECT | Nizar et al · The Breast | 2013 | Klinik Çalışma | İnsan | – | 18 | – | bleomisin | nesnel yanıt 80.5% | Locally advanced breast cancer (LABC) remains a common daily clinical encounter in many parts of the world including the Middle East. Improvement in the outcome of patients with breast cance… |
| ECT | Oom et al · The Breast | 2013 | Klinik Çalışma | İnsan | – | 10 | – | bleomisin | tam yanıt 53% (17 seans) | The presence of HER2 overexpression predicts a poor prognosis for patients. It is associated with a high rate of disease progression despite the widespread use of HER2-targeted therapies. Th… |
| ECT | Benevento et al · BMC Surg | 2012 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | 12 / 142 | Cliniporator | bleomisin · intravenöz | tam yanıt 75.3% (142 lezyon) | Background: The management of cutaneous metastases often represents a challenge because they may be widespread and may recur after radiotherapy or chemotherapy; breast cancer accounts for 51… |
| ECT | Cabula · European Journal of Surgical Oncology (EJSO) | 2012 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | 1 | – | bleomisin · intravenöz | – | Electrochemotherapy (ECT), a new palliative treatment for cutaneous metastases, involves the delivery of electrical pulses to lesions several minutes after intravenous or intratumor injectio… |
| ECT | Campana et al · Breast Cancer Res Treat | 2012 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | 35 / 196 | – | bleomisin · intravenöz | nesnel yanıt 91.4% (35 hasta) | Electrochemotherapy (ECT) represents an attractive locoregional therapy for unresectable chest wall recurrence (CWR) from breast cancer. Thirty-five patients with cutaneous CWR after mastect… |
| ECT | Matthiessen et al · Acta Oncol | 2012 | Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | 17 / 25 | Cliniporator | bleomisin · intravenöz | nesnel yanıt 0.17 oran (12 hasta) | Background: Cutaneous recurrences of breast cancer may cause considerable discomfort due to ulceration, oozing, and pain and can also be difficult to treat. Electrochemotherapy is a localise… |
| ECT | Sersa et al · Radiotherapy and Oncology | 2012 | Klinik Çalışma | Hayvan (İn Vivo) | – | – | – | bleomisin · intravenöz | – | Bu yayında özet bulunmuyor. |
| ECT | Matthiessen et al · European Journal of Cancer Supplements | 2009 | Klinik Çalışma | İnsan | – | 5 | square wave electroporator | bleomisin · intravenöz | – | Bu yayında özet bulunmuyor. |
| ECT | Whelan et al · European Journal of Cancer Supplements | 2006 | Klinik Çalışma | İnsan | – | 1 | – | bleomisin · hem intravenöz hem intratümöral | – | The application of combined chemotherapy and cancer cell permeabilising electric pulses (electrochemotherapy) has been demonstrated here to be clinically effective in the treatment and contr… |
| ECT | Rebersek et al · Anticancer Drugs | 2004 | Klinik Çalışma | İnsan | Sisplatin Hücre İçi Birikiminin Artması | – | – | – | – | We have evaluated the efficiency of electrochemotherapy with cisplatin on cutaneous tumor lesions of breast cancer and have compared its efficiency with the efficiency of intratumoral (i.t.)… |
| ECT | Sena et al · Eur J Surg Oncol | 2026 | Retrospektif Klinik Çalışma | İnsan | – | 19 | Cliniporator | bleomisin · intravenöz | tam yanıt 11 adet (11 hasta) | Background: Cutaneous and subcutaneous recurrence of breast cancer represents a challenging clinical scenario, particularly in patients previously treated with surgery, radiotherapy, and sys… |
| ECT | Russano et al · Front Oncol | 2021 | Retrospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | 55 | Cliniporator | bleomisin · hem intravenöz hem intratümöral | tam yanıt 64% (55 hasta) | The treatment of cutaneous and subcutaneous localizations from breast cancer (BC) is still a therapeutic challenge. Electrochemotherapy (ECT) is one of the available options, and it is chara… |
| ECT | Cabula et al · Ann Surg Oncol | 2015 | Retrospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | 125 / 239 | – | bleomisin · intravenöz | nesnel yanıt 90.2% (113 hasta) | Background: The management of breast cancer (BC) skin metastases represents a therapeutic challenge. Electrochemotherapy (ECT) combines the administration of bleomycin with temporary permeab… |
| ECT | Campana et al · J Cancer Res Clin Oncol | 2014 | Retrospektif Klinik Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması | 55 / 212 | – | bleomisin · hem intravenöz hem intratümöral | nesnel yanıt 40% (55 hasta) | Purpose: To evaluate the efficacy and toxicity of electrochemotherapy (ECT) in elderly metastatic breast cancer (BC) patients. Methods: Retrospective analysis of 55 patients with superficial… |
| ECT | Shahverdi et al · Int J Cancer Manag | 2026 | Vaka Serisi | İnsan | – | 10 | – | bleomisin · intravenöz | tam yanıt 2 adet (10 hasta) | Background and Objective: Breast cancer (BC), the second most prevalent cancer worldwide, poses a significant health challenge. Despite major advances in therapeutic modalities for BC, patie… |
| ECT | Mazzotti · IJCCR | 2024 | Vaka Raporu | İnsan | – | 1 / 1 | Cliniporator | bleomisin · intratümöral | – | Electrochemotherapy represents one of the therapeutic breakthroughs in the oncology field. In this case report, we describe a woman diagnosed with breast cancer in 2005. The case was treated… |
| ECT | Corrado et al · Anticancer Res | 2023 | Vaka Raporu | İnsan | – | 1 | – | bleomisin · intravenöz | lokal nüks 0 adet (1 hasta) | Background: We present the case of a recurrent malignant phyllodes tumor of the breast, after mastectomy and radiotherapy, in which electrochemotherapy (ECT) was applied to the tumor bed, to… |
| ECT | Campana et al · J Surg Case Rep | 2022 | Vaka Raporu | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Elektrot Geometrisi ve Yerleşimi | 1 / 1 | – | bleomisin · intravenöz | – | A 55-year-old woman with previous skin-sparing mastectomy and prosthetic reconstruction for multifocal ductal carcinoma developed homolateral axillary recurrence. Following nodal dissection,… |
| Kalsiyum EP | Jensen · Case Rep Dermatol | 2022 | Vaka Raporu | İnsan | Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Kalsiyum Homeostazının Bozulması | 1 | Cliniporator | kalsiyum klorür · intratümöral | tam yanıt 1 adet (1 hasta) | We report a case of successful treatment of cutaneous metastases in HER2-positive breast cancer with calcium electroporation (CaEP), in addition to trastuzumab, over a period of 5 years. CaE… |
| ECT | Esposito et al · Transl Cancer Res | 2021 | Vaka Raporu | İnsan | Nekroz ve Nekroptoz, Bleomisin Hücre İçi Birikiminin Artması | 1 | Cliniporator | bleomisin · intravenöz | tam yanıt 1 adet (1 hasta) | Electrochemotherapy has been shown to be safe, effective and non-invasive loco-regional treatment for chest wall breast cancer recurrence. Electrochemotherapy is a palliative treatment offer… |
| ECT | Cencelj-Arnez et al · Radiol Oncol | 2020 | Vaka Raporu | İnsan | – | 1 / 40 | Cliniporator | bleomisin · intravenöz | tam yanıt 100% (6 lezyon) | Background: Radiotherapy-associated angiosarcoma (RAA) of the breast is a rare complication of radiotherapy, which is often difficult to identify and has poor prognosis. It usually presents … |
| ECT | Esposito et al · – | 2020 | Vaka Raporu | – | Nekroz ve Nekroptoz, Darbe Parametrelerinin Optimizasyonu | – | Cliniporator | bleomisin · intravenöz | – | Background Electrochemotherapy has been shown to be safe, effective and non-invasive loco-regional treatment for chest wall breast cancer recurrence. Electrochemotherapy is the gold standard… |
| ECT | Radica et al · AME Case Rep | 2020 | Vaka Raporu | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Nekroz ve Nekroptoz | 1 / 1 | Cliniporator | bleomisin · intravenöz | lokal kontrol 30 gün (1 hasta) | Breast cancer is the most common cause of chest wall recurrence, skin, and subcutaneous tissue metastases which mainly occur as multiple nodes in the skin and subcutaneous tissue. When it oc… |
| ECT | Di Meo et al · J Eur Acad Dermatol Venereol | 2019 | Vaka Raporu | İnsan | – | 1 / 5 | – | bleomisin · intravenöz | tam yanıt 1 adet (1 hasta) | N/A |
| ECT | Mofid et al · Acta Med Iran | 2017 | Vaka Raporu | İnsan | Kas Kasılması ve Anestezi Gereksinimi | 1 / 1 | ECT-SBDC | bleomisin · intravenöz | tümör hacmi değişimi 47% (1 hasta) | Electrochemotherapy (ECT) is a new local treatment method for solid and superficial tumors. During this new technique, patients experience an unpleasant sensation and slight edema. Most unpl… |
| ECT | Wichtowski et al · Breast Care (Basel) | 2016 | Vaka Raporu | İnsan | – | 1 | – | – · intravenöz | – | Background: Chest wall recurrence (CWR) from breast cancer after mastectomy is a difficult to treat disease. Electrochemotherapy (ECT) provides a safe, efficient, and non-invasive locoregion… |
| ECT | Cabula · Updates Surg | 2012 | Vaka Raporu | İnsan | – | 1 / 1 | Cliniporator | bleomisin · intravenöz | tam yanıt 0 ay (1 hasta) | Neoadjuvant electrochemotherapy of breast cancer: our experience on first case treated in Italy Carlo Cabula Received: 29 December 2010 / Accepted: 17 July 2012 / Published online: 12 August… |
| ECT | Ferioli et al · Clin Exp Metastasis | 2020 | Sistematik Derleme / Meta-Analiz | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | – | bleomisin · intravenöz | – | Skin metastases occur in 5-30% of breast cancer (BC) patients. Standard treatments include systemic therapies (chemotherapy, endocrine therapy, and immunotherapy) and local treatments (surge… |
| Diğer EP | Russano et al · Ther Adv Med Oncol | 2025 | Derleme | Literatür Analizi | – | – | – | bleomisin · intravenöz | tam yanıt 81.5% | Cutaneous metastases from breast cancer, although relatively uncommon, represent the most frequent form of skin metastases overall and pose a significant clinical and therapeutic challenge. … |
| ECT | Russano et al · Biomedicines | 2025 | Derleme | Literatür Analizi | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | – | bleomisin · intravenöz | nesnel yanıt 87% (55 hasta) | Cutaneous metastases from breast carcinoma represent a debilitating complication of advanced disease progression, significantly impacting patients' quality of life. Electrochemotherapy (ECT)… |
| ECT | Campana et al · Handbook of Electroporation | 2017 | Derleme | Literatür Analizi | – | – | – | bleomisin · intravenöz | nesnel yanıt 90.2% (125 hasta) | Skin metastases occur more commonly in breast cancer (BC) than in any other malignancy in women, exceeding 20% of all cutaneous metastases. They most commonly present on the chest wall (CW),… |
| ECT | Wichtowski et al · Breast Care (Basel) | 2017 | Derleme | Literatür Analizi | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – | – | diğer · hem intravenöz hem intratümöral | – | Breast cancer is the most common cause of skin metastases in women. The probability of their occurrence ranges from about 5% in the entire population to as much as 30% in the late stages of … |
| IRE | Thomson et al · Tech Vasc Interv Radiol | 2015 | Derleme | İnsan | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | – | – | – | – | Irreversible electroporation (IRE) is a novel nonthermal focal ablation technique that uses a series of brief but intense electric pulses delivered by paired electrodes into a targeted regio… |
| ECT | Schmidt et al · Geburtshilfe Frauenheilkd | 2014 | Derleme | Literatür Analizi | – | – | – | bleomisin · intravenöz | nesnel yanıt 84.1% (1894 lezyon) | Electrochemotherapy is a new method for the local treatment of cutaneous and subcutaneous metastases. If surgery and/or radiotherapy are no longer possible, this innovative technology can be… |
| ECT | Sersa et al · Cancer Treat Rev | 2012 | Derleme | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Sisplatin Hücre İçi Birikiminin Artması | – / 171 | – | bleomisin · intravenöz | nesnel yanıt 95% (58 lezyon) | Chest wall breast cancer recurrence after mastectomy is a disease difficult to treat. Its incidence varies between 5% and 30% in different subset of patients. When possible, radical surgical… |
| ECT | Radzevičiūtė-Valčiukė et al · Front Immunol | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Doku İletkenliği ve Empedans Değişimi, Darbe Parametrelerinin Optimizasyonu | – | square-wave unipolar and bipolar pulse generator developed a | kalsiyum klorür · intratümöral | tam yanıt 70% (13 hayvan) | Calcium electrochemotherapy (CaECT) is an effective alternative to standard chemotherapeutic treatments, utilizing intracellular delivery of supraphysiological calcium concentrations to indu… |
| ECT | YazdanParast et al · Biomedicines | 2026 | Hayvan Çalışması | Hayvan (İn Vivo) | Reversible Membran Permeabilizasyonu, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | Oncopore | diğer · intratümöral | tümör hacmi değişimi 0.5 oran (5 hayvan) | Background : Electrochemotherapy enhances the intracellular delivery of anticancer agents through electroporation but is traditionally limited to cytotoxic drugs associated with significant … |
| Kalsiyum EP | Barauskaitė-Šarkinienė et al · Int J Mol Sci | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, İrreversible Por Oluşumu ve Hücre Ölümü | – | Amber Charge pulse generator | bleomisin · diğer yol | – | Electrochemotherapy (ECT) uses electroporation to enhance drug delivery into tumor cells, triggering bystander effects like immunogenicity and cell death. This study investigated bystander e… |
| ECT | Omerzel et al · Cancers (Basel) | 2025 | Hayvan Çalışması | Hayvan (İn Vivo) | İmmün Kontrol Noktası İnhibitörü Kombinasyonu, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | GT-01, ELECTRO cell B10 | bleomisin · intravenöz | tam yanıt 100% (12 hayvan) | Background : Electrochemotherapy (ECT) is a clinically validated local ablative treatment increasingly recognized for its ability to induce immunogenic cell death and stimulate antitumor imm… |
| Diğer EP | Pastori et al · J Vasc Interv Radiol | 2024 | Hayvan Çalışması | Hayvan (İn Vivo) | Sistemik / Abskopal İmmün Yanıt, Nekroz ve Nekroptoz | – | Aliya, RF3000 | – | – | Purpose: To compare the immune response and survival after size-matched radiofrequency (RF) ablation and a proprietary form of pulsed electric field (PEF) ablation in murine tumors. Material… |
| ECT | Bosnjak et al · Bioelectrochemistry | 2021 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, DNA Hasarı ve Çift Zincir Kırıkları | – | ELECTRO Cell B10 | bleomisin · intravenöz | – | Electrochemotherapy (ECT), a local therapy, has different effectiveness among tumor types. In breast cancer, its effectiveness is low; therefore, combined therapies are needed. The aim of ou… |
| Gen ET | Guo · Front Immunol | 2020 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | – | BTX ECM830 | plazmid DNA · intratümöral | tam yanıt 25% (8 hayvan) | Interleukin 15 (IL-15) has been evaluated as a potential treatment for solid tumors in clinical trials, but the effectiveness of systemic IL-15 administration as a monotherapy has not been r… |
| ECT | Sundararajan et al · Biomedicines | 2020 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | BTX ECM830, needle array electrodes | diğer · intratümöral | tümör hacmi değişimi 16.67% (6 hayvan) | In the US, every 12 min, six women are diagnosed with breast cancer and one dies. This highlights a critical need for developing alternate therapies using natural compounds, which are cost e… |
| Gen ET | Savarin · Technol Cancer Res Treat | 2018 | Hayvan Çalışması | Hayvan (İn Vivo) | Antivasküler Etki ve Damar Yıkımı, Gen Elektrotransferi (Plazmid DNA) | – | ELECTRO cell B10 | – · intratümöral | – | Vascular-targeted therapies exhibit radiosensitizing effects by remodeling tumor vasculature, thus facilitating the increased oxygenation of the remaining tumor tissue. To examine these phen… |
| ECT | Lanza et al · J Vet Med Sci | 2017 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – / 2 | Onkodisruptor | sisplatin · intratümöral | hastalıksız sağkalım 10 ay (2 hasta) | Two male rats (Rattus norvegicus; 18 and 24 months old), were referred for treatment of large masses located in the axillary area. Following total body radiography and hematological and seru… |
| IRE | Zhang et al · PLoS One | 2017 | Hayvan Çalışması | Hayvan (İn Vivo) | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | – | NanoKnife | – | – | Background and aim: Irreversible electroporation (IRE) was confirmed to control several solid tumors effectively in vivo. Our preclinical study aimed to assess the feasibility and safety of … |
| IRE | Zhang et al · Biomed Microdevices | 2017 | Hayvan Çalışması | Hayvan (İn Vivo) | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | – | NanoKnife | – | – | Irreversible electroporation (IRE) is considered predominantly as a non-thermal ablative technique that uses electrical fields to permeabilize cell membranes and lead to cell death. In this … |
| Gen ET | Stimac · PLoS One | 2015 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA), Antivasküler Etki ve Damar Yıkımı | – | GT-01, ELECTRO cell B10 HVLV | plazmid DNA · intratümöral | – | Vascular targeted therapies, targeting specific endothelial cell markers, are promising approaches for the treatment of cancer. One of the targets is endoglin, transforming growth factor-β (… |
| ECT | Mahna et al · J Membr Biol | 2013 | Hayvan Çalışması | Hayvan (İn Vivo) | Darbe Parametrelerinin Optimizasyonu, Bleomisin Hücre İçi Birikiminin Artması | – | ECTS-BDC | bleomisin · intratümöral | – | From a fundamental point of view, chemotherapy is the most widely used treatment for cancers despite its side effects on normal cells and tissues. Electrochemotherapy (ECT) is a method for i… |
| ECT | Raeisi et al · Radiol Oncol | 2012 | Hayvan Çalışması | Hayvan (İn Vivo) | Sisplatin Hücre İçi Birikiminin Artması | – | – | sisplatin · intratümöral | – | Background: The aim of this study was to investigate the antitumor effectiveness of electrochemotherapy with cisplatin combined with suboptimal radiotherapy doses. Tumor radiosensitization w… |
| Diğer EP | Haller et al · Oncogene | 2010 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | – | Derma Vax | plazmid DNA · intratümöral | tümör hacmi değişimi 64% (8 hayvan) | The Notch ligand delta-like ligand 4 (DLL4) is an essential component expressed by endothelial tip cells during angiogenic sprouting. We have described a conceptually novel therapeutic strat… |
| Gen ET | Shibata · BMC Med | 2010 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA), Apoptoz İndüksiyonu | – | CUY21EDIT square-wave electropulser | plazmid DNA · intratümöral | – | Background: Cancer metastasis contributes significantly to cancer mortality and is facilitated by lymphangiogenesis and angiogenesis. A new splicing variant, endogenous soluble vascular endo… |
| IRE | Neal et al · Breast Cancer Res Treat | 2010 | Hayvan Çalışması | Hayvan (İn Vivo) | İrreversible Por Oluşumu ve Hücre Ölümü, Elektrik Alan Dağılımı ve Modellemesi | – | – | – | tümör hacmi değişimi 0.714286 oran (7 lezyon) | Irreversible electroporation (IRE) is a therapeutic technology for the ablation of soft tissues using electrodes to deliver intense but short electric pulses across a cell membrane, creating… |
| Gen ET | Shibata et al · Cancer Gene Ther | 2008 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | – | CUY21EDIT square-wave electropulser | – | – | Cancer metastasis contributes significantly to cancer mortality and is facilitated by lymphangiogenesis and angiogenesis. Vascular endothelial growth factor-C (VEGF-C) and VEGF-A are involve… |
| Diğer EP | Anon · Molecular Therapy | 2007 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA) | – | – | plazmid DNA · intratümöral | – | Earlierstudies by our group have demonstrated the potential of branched Polyethyleneimine (PEl, 70Kd) conjugated poly(lactide-co-glycolide)PLGAmicroparticles forenhanced in vitro transfectio… |
| Gen ET | Curcio et al · Cancer Gene Ther | 2007 | Hayvan Çalışması | Hayvan (İn Vivo) | – | – | – | plazmid DNA · intratümöral | – | A recently developed, adaptive constant-current electroporation technique was used to immunize mice with an intramuscular injection of plasmid coding for the extracellular and transmembrane … |
| Diğer EP | Wells et al · Gene Ther | 2000 | Hayvan Çalışması | Hayvan (İn Vivo) | Gen Elektrotransferi (Plazmid DNA), Elektrik Alan Dağılımı ve Modellemesi | – | Velonex model 345 pulse generator | plazmid DNA · intratümöral | – | Electroporation was applied to enhance gene transfer into subcutaneous MC2 murine breast tumors. Cultured MC2 cells were also transfected by electroporation or by cationic liposomes in the p… |
| ECT | Belehradek et al · Eur J Cancer | 1991 | Hayvan Çalışması | Hayvan (İn Vivo) | Bleomisin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – / 38 | Bioblock | bleomisin · diğer yol | tam yanıt 10 adet (18 lezyon) | Electrochemotherapy delivers external electric pulses to the tumour site to induce local potentiation of the antitumour activity of intramuscular injections of bleomycin. C3H/Bi mice with sp… |
| ECT | Rembiałkowska et al · Bioelectrochemistry | 2026 | İn Vitro Çalışma | Hücre Kültürü | Bleomisin Hücre İçi Birikiminin Artması, Mitokondriyal Disfonksiyon ve Oksidatif Stres | – | BTX ECM830 | bleomisin | – | Electrochemotherapy (ECT), combining pulsed electric fields (PEFs) with cytotoxic drugs, enhances intracellular drug delivery and tumor control; however, cellular stress responses determinin… |
| Diğer EP | Wei et al · Bioelectrochemistry | 2026 | İn Vitro Çalışma | Hücre Kültürü | Mitokondriyal Disfonksiyon ve Oksidatif Stres, İmmünojenik Hücre Ölümü (ICD) | – | – | – | hücre canlılığı 16.3% | This study aimed to investigate the synergistic effect of cold atmospheric plasma (CAP) and pulsed electric field (PEF) in inducing immunogenic cell death (ICD) in triple-negative breast can… |
| ECT | Yetişsin et al · Artvin Çoruh Üniversitesi Orman Fakültesi Dergisi | 2025 | İn Vitro Çalışma | Hücre Kültürü | – | – | BTX Gemini X2 | – | – | The aim of the current study was to determine the phenolic substances in the stem of Asparagus officinalis L, leaves of Arum elongatum Steven and Urtica dioica L. plants collected from diffe… |
| ECT | Michel et al · Front Oncol | 2025 | İn Vitro Çalışma | Hücre Kültürü | Reversible Membran Permeabilizasyonu, Nanosaniye Darbeli Elektrik Alan (nsPEF) | – | custom-made square-wave high-voltage pulse generator | diğer · diğer yol | hücre canlılığı 5.6% | Introduction: Electroporation (EP) is a technique that transiently increases the permeability of the cell membrane through the application of high-voltage electric pulses, facilitating the i… |
| Diğer EP | Safaei et al · Bioelectromagnetics | 2025 | İn Vitro Çalışma | Hücre Kültürü | Apoptoz İndüksiyonu, Reversible Membran Permeabilizasyonu | – | BTX Gemini X2 | – | – | Breast cancer is the second-leading cancer-related death among women. Survival rates decrease from 99% for localized stages of breast tumors to only 27% when distant metastases develop. Incr… |
| ECT | Lekešytė et al · Pharmaceutics | 2024 | İn Vitro Çalışma | İnsan | Bleomisin Hücre İçi Birikiminin Artması, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | VilniusTECH pulse generator | bleomisin | hücre canlılığı 80% | Background/Objectives: Electrochemotherapy (ECT) is a safe and efficient method of targeted drug delivery using pulsed electric fields (PEF), one that is based on the phenomenon of electropo… |
| ECT | Cvetkovic et al · Experimental and Applied Biomedical Research (EABR) | 2023 | İn Vitro Çalışma | Hücre Kültürü | Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü | – | ECM 399 Generator, BTX-Harvard Apparatus ECM 399 Generator | diğer | – | Despite advances in treatment, breast cancer remains one of the leading causes of death, and obviously new approaches to the treatment are needed. Due to minimal side effects, unlike more ag… |
| ECT | Giri et al · Explor Target Antitumor Ther | 2023 | İn Vitro Çalışma | Hücre Kültürü | Mitokondriyal Disfonksiyon ve Oksidatif Stres, Apoptoz İndüksiyonu | – | BTX ECM830 | diğer · diğer yol | – | Aim: Triple negative breast cancer (TNBC) is difficult to treat since it lacks all the three most commonly targeted hormone receptors. Patients afflicted with TNBC are treated with platinum … |
| ECT | Bute et al · Med Oncol | 2022 | İn Vitro Çalışma | Hücre Kültürü | Darbe Parametrelerinin Optimizasyonu | – | – | diğer | – | Traditional cancer treatments, such as chemotherapy and radiotherapy have several limitations. Therefore, their performance must be enhanced with combined methods. The purpose of this study … |
| ECT | Rembiałkowska et al · Molecules | 2022 | İn Vitro Çalışma | Hücre Kültürü | Mitokondriyal Disfonksiyon ve Oksidatif Stres, Darbe Parametrelerinin Optimizasyonu | – | PPG-20 | diğer | – | (1) Background: Pulsed electric field (PEF) techniques are commonly used to support the delivery of various molecules. A PEF seems a promising method for low permeability drugs or when cells… |
| ECT | Varadarajan et al · Appl Biochem Biotechnol | 2022 | İn Vitro Çalışma | Hücre Kültürü | – | – | BTX ECM830 | diğer | – | With the absence of the three most common receptor targets, and with high vascularity and higher-grade tumors, triple-negative breast cancer (TNBC) is the most aggressive of all breast cance… |
| IRE | Jiang et al · Biosensors (Basel) | 2022 | İn Vitro Çalışma | Hücre Kültürü | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | – | BTX ECM830 | – | – | Irreversible electroporation (IRE) is a non-thermal tumor ablation technique that delivers short pulses of strong electric fields to cancer tissues and induces cell death through the destruc… |
| ECT | Abd-Elghany · Electromagn Biol Med | 2021 | İn Vitro Çalışma | Hücre Kültürü | Nanosaniye Darbeli Elektrik Alan (nsPEF), Reversible Membran Permeabilizasyonu | – | Grass S44 Stimulator, FID Technologies pulsar | bleomisin | – | The study aimed to evaluate the possibility to perform electrochemotherapy using nanosecond pulsed electric field (nsPEF) and low electric field (LEF) monopolar electrical impulses to allevi… |
| ECT | Sundararajan et al · Appl Biochem Biotechnol | 2021 | İn Vitro Çalışma | Hücre Kültürü | Sisplatin Hücre İçi Birikiminin Artması, Apoptoz İndüksiyonu | – | BTX ECM830 | sisplatin | – | Heat shock proteins (HSPs) are available and/or induced for the survival of all organisms, including eukaryotic, prokaryotic, and plants, from higher temperature stresses. They are the chape… |
| ECT | Mittal et al · Bioelectrochemistry | 2020 | İn Vitro Çalışma | Hücre Kültürü | Apoptoz İndüksiyonu | – | BTX ECM830 | diğer | – | Curcumin (Cur), the yellow pigment of well-known turmeric (Curcuma longa L.) is effective in multiple cancers including triple negative breast cancer (TNBC). In combination with electrical p… |
| ECT | Mittal et al · Sci Rep | 2020 | İn Vitro Çalışma | Hücre Kültürü | Mitokondriyal Disfonksiyon ve Oksidatif Stres | – | BTX ECM830 | diğer · intratümöral | hücre canlılığı 9% (4 örnek) | Triple negative breast cancer (TNBC) represents 15-20% of the over one million new breast cancer cases occurring each year. TNBC is an aggressive cancer phenotype, with low 5-year survival r… |
| Diğer EP | Rembiałkowska et al · Applied Sciences | 2020 | İn Vitro Çalışma | Hücre Kültürü | Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | BTX ECM830 | diğer | – | Electroporation increases the transmembrane transport of molecules. The combination of electric pulses with cytostatic compounds is beneficial for cancer treatment. Doxorubicin (DOX) is a co… |
| Gen ET | Sieni · Cancers (Basel) | 2020 | İn Vitro Çalışma | Hücre Kültürü | Gen Elektrotransferi (Plazmid DNA), Ekstraselüler Matriks ve Doku İskeletinin Korunması | – | EPS-01 | plazmid DNA | – | Gene Electro-Transfer (GET) is a powerful method of DNA delivery with great potential for medical applications. Although GET has been extensively studied in vitro and in vivo, the optimal pa… |
| Diğer EP | Sieni et al · Bioelectrochemistry | 2020 | İn Vitro Çalışma | Hücre Kültürü | Reversible Membran Permeabilizasyonu, Ekstraselüler Matriks ve Doku İskeletinin Korunması | – | EPS-01 | – | – | Nowadays, electroporation (EP) represents a promising method for the intracellular delivery of anticancer drugs. To setting up the process, the EP efficiency is usually evaluated by using ce… |
| IRE | Vera-Tizatl et al · Electromagn Biol Med | 2020 | İn Vitro Çalışma | Hücre Kültürü | Reversible Membran Permeabilizasyonu, İrreversible Por Oluşumu ve Hücre Ölümü | – | BTX830 Square Wave Electroporation System, Gene Pulser | – | – | In order to establish cancer-type-specific electroporation protocols for breast cancer, electroporation was performed in vitro in two modalities: in-suspension and adhered cells. Electropora… |
| ECT | Aslam et al · RSC Adv | 2019 | İn Vitro Çalışma | Hücre Kültürü | Transmembran Potansiyel Değişimi, Elektrik Alan Dağılımı ve Modellemesi | – | – | – | – | Electroporation has offered important biomedical applications in electrochemotherapy, tissue ablation and gene editing recently. Time and computation efficient analytical and numerical model… |
| Kalsiyum EP | Hoejholt et al · Sci Rep | 2019 | İn Vitro Çalışma | Hücre Kültürü | Kalsiyum Elektroporasyonu ve ATP Tükenmesi, Bleomisin Hücre İçi Birikiminin Artması | – | BTX T820 | kalsiyum klorür · intratümöral | – | Calcium electroporation is a novel anti-cancer treatment investigated in clinical trials. We explored cell sensitivity to calcium electroporation and electroporation with bleomycin, using vi… |
| ECT | Mittal et al · Sci Rep | 2019 | İn Vitro Çalışma | Hücre Kültürü | Sisplatin Hücre İçi Birikiminin Artması, Apoptoz İndüksiyonu | – | BTX ECM830 | sisplatin | progresif hastalık 507 adet | Due to the lack of the three main receptors, triple negative breast cancer (TNBC) is refractive to standard chemotherapy. Hence, alternate therapies are needed. TNBCs utilize glycolysis, whi… |
| ECT | Weżgowiec et al · Bioelectrochemistry | 2018 | İn Vitro Çalışma | Hücre Kültürü | Reversible Membran Permeabilizasyonu, Apoptoz İndüksiyonu | – | BTX ECM830 | diğer | – | Electrochemotherapy became one of the therapeutic protocols successfully used in oncology. However, biological effects occurring in cells, especially those which are drug resistant, have not… |
| IRE | Goswami et al · Bioelectrochemistry | 2017 | İn Vitro Çalışma | Hücre Kültürü | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | – | Harvard Apparatus electroporation unit | – | – | Low-level electric fields have been demonstrated to induce spatial re-distribution of cell membrane receptors when applied for minutes or hours. However, there is limited literature on the i… |
| Diğer EP | Wezgowiec et al · Photodiagnosis Photodyn Ther | 2013 | İn Vitro Çalışma | Hücre Kültürü | Reversible Membran Permeabilizasyonu, Sitotoksik İlaç Geçirgenliğinin Potansiyalizasyonu | – | BTX ECM830, BetaTech, Petri Pulser applicator | diğer | – | Background: Ineffective drug delivery is a vast problem of anticancer therapies. The aim of this study was to investigate the possibility of enhancement of cyanines transport through the cel… |
| Diğer EP | Pehlivanova et al · Cancer Cell Int | 2012 | İn Vitro Çalışma | Hücre Kültürü | Reversible Membran Permeabilizasyonu | – | Chemipulse III | – | – | Background: Recently electroporation using biphasic pulses was successfully applied in clinical developments for treating tumours in humans and animals. We evaluated the effects of electrica… |
| Diğer EP | Kulbacka et al · Folia Biol (Praha) | 2011 | İn Vitro Çalışma | Hücre Kültürü | – | – | BTX ECM830 | diğer · diğer yol | – | Phototoxicity of drugs used in cancer photodynamic therapy could be augmented by increased accumulation of a photosensitizer in target cells. The intracellular delivery mode that enhances dr… |
| IRE | Neal et al · Ann Biomed Eng | 2009 | İn Vitro Çalışma | Hücre Kültürü | İrreversible Por Oluşumu ve Hücre Ölümü, Reversible Membran Permeabilizasyonu | – | 96-Well Electroporation Plate System, Vi-Cell Cell Viability Analyzer | – | hücre canlılığı 5% (12 örnek) | Developments in breast cancer therapies show potential for replacing simple and radical mastectomies with less invasive techniques. Localized thermal techniques encounter difficulties, preve… |
| ECT | Vera-Tizatl et al · Technol Cancer Res Treat | 2018 | İn Siliko / Modelleme | İnsan | Elektrot Geometrisi ve Yerleşimi, Elektrik Alan Dağılımı ve Modellemesi | – / 3 | – | – | – | Breast cancer represents a rising problem concerning public health worldwide. Current efforts are aimed to the development of new minimally invasive and conservative treatment procedures for… |
| ECT | Łapińska et al · Adv Clin Exp Med | 2022 | Editöryal / Mektup | İnsan | – | – | – | – | – | Breast cancer (BC) is the most common cancer in women, and its incidence is increasing every year. Current treatment is based on surgical resection, chemotherapy (CT), radiotherapy, and horm… |
| ECT | Bourke et al · Breast Cancer Res Treat | 2017 | Editöryal / Mektup | İnsan | – | – | – | bleomisin | – | , We read with interest Bourke et al.’s paper on the treatment of cutaneous metastases from breast cancer (BC) with electrochemotherapy (ECT) [1]. In a highly pretreated population—whose sur… |
| ECT | Campana et al · Breast Cancer Res Treat | 2017 | Editöryal / Mektup | İnsan | – | – | – | bleomisin · hem intravenöz hem intratümöral | nesnel yanıt 68.6% (236 lezyon) | Breast Cancer Res Treat (2017) 163:403–405 DOI 10.1007/s10549-017-4187-7 REBUTTAL LETTER Effective treatment of intractable cutaneous metastases of breast cancer with electrochemotherapy: a … |
| ECT | Bosnjak et al · Bioelectrochemistry | 2021 | Düzeltme / Erratum | Hayvan (İn Vivo) | – | – | – | bleomisin | – | Bioelectrochemistry 141 (2021) 107865 Contents lists available at ScienceDirect Bioelectrochemistry journal homepage: www.elsevier.com/locate/bioelechem Corrigendum Corrigendum to ‘‘PARP inh… |
| ECT | Mittal et al · Sci Rep | 2019 | Düzeltme / Erratum | Hücre Kültürü | Sisplatin Hücre İçi Birikiminin Artması | – | – | sisplatin | – | An amendment to this paper has been published and can be accessed via a link at the top of the paper. |
| ECT | Bourke et al · Breast Cancer Res Treat | 2017 | Düzeltme / Erratum | – | – | – | – | – | – | Bu yayında özet bulunmuyor. |
| ECT | Poompavai et al · IEEE Trans. Radiat. Plasma Med. Sci. | 2020 | Belirtilmemiş | – | Termal Etki ve Joule Isınması | – | – | – | – | Short intense electric pulses surpass the capacitance of the cell membrane and leads to permeabilization [electroporation (EP)]. EP can be reversible [electrochemotherapy (ECT)] or irreversi… |
| ECT | Agresti et al · The Breast | 2017 | Protokol | İnsan | – | 500 | – | bleomisin | – | The multicentre cohort analysis conducted by GISEL (Italian Senological Group for Electrochemotherapy) confirmed that Electrochemotherapy (ECT) has high antitumor activity (> 90% ORR) on ski… |
| ECT | Banerjee et al · European Journal of Surgical Oncology (EJSO) | 2016 | Belirtilmemiş | – | – | – | – | bleomisin · intravenöz | – | Bu yayında özet bulunmuyor. |
| ECT | Zheng et al · Gland Surg | 2012 | Belirtilmemiş | – | – | 35 | – | – | – | Luca G. Campana, MD, PhD, Sarcoma and Melanoma Unit, Veneto Region Oncology Research Institute (IOVIRCCS) (Figure 1). |
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Sınırlılıklar
Yayın hacmi klinik etkinlik ya da kanıt kalitesi değildir. Alanda ne kadar ve hangi türde literatür bulunduğunu tarif eder; tedavinin ne kadar kanıtlandığını, kılavuz onayını ya da regülasyon durumunu göstermez.
Hasta toplamları benzersiz hasta sayısı değildir. Aynı kohort birden fazla yayında raporlanmış olabilir; toplamlar bir meta-analiz değildir.
Korpusun nasıl derlendiği, kademe eşikleri, klinik yayın tanımı ve yöntemlerin birbirinden ayrı sayılması: Literatür Haritası.