Devices & Clinical Trials
Basic Science
Device documentation and clinical trial records are gathered under this heading. Because the area contains technical documents and registry data rather than peer-reviewed literature, it differs in character from the others.
Evidence Status by Regime
Reversible electroporation (RE-ECT)
Exploratory Evidence
2017–2021 · Early Research Stage
Irreversible electroporation (IRE-ECT)
Exploratory Evidence
2007–2017 · Early Research Stage
Mechanisms Reported in This Area
Terms were detected by automatic matching over publication abstracts; the figure gives the number of publications containing the term.
Study Type Distribution
Bar length is scaled to the most common study type; the percentage gives the share of the whole area. Colour marks the evidence tier of the study type, the same scale as the evidence map.
| Study type | Publications | Share within this area |
|---|---|---|
| Clinical Study | 1 | 12% |
| Review | 5 | 62% |
| Technical / Device Study | 1 | 12% |
| Protocol | 1 | 12% |
Literature Evidence Table
8 publications listed in order of evidence strength. Click a title to open the citation, mechanism and full abstract drawer.
| Regime | Publication | Year | Study type | Model | Mechanism | Abstract |
|---|---|---|---|---|---|---|
| Irreversible | Bertacchini et al · Technol Cancer Res Treat | 2007 | Clinical Study | Human | Reversible Membrane Permeabilisation, Irreversible Pore Formation and Cell Death | Irreversible electroporation is an ablation modality in which microseconds, high-voltage electrical pulses are applied to induce cell necrosis in a target tissue. To perform irreversible ele… |
| Reversible | Granata et al · Eur Rev Med Pharmacol Sci | 2021 | Review | Human | Irreversible Pore Formation and Cell Death, Reversible Membrane Permeabilisation | Electroporation (EP) techniques, used alone (Irreversible Electroporation, IRE) or in combination with anti-cancer drugs (Electrochemotherapy, ECT), have been shown to be effective in the tr… |
| Reversible | Bertacchini · Handbook of Electroporation | 2017 | Review | Literature Analysis | Gene Electrotransfer (Plasmid DNA) | The development of the medical device Cliniporator™ started in 2000 with the homonymous European project, and, at its end, the prototype of the device was ready to be certified. The work done… |
| Reversible | Brizio et al · Handbook of Electroporation | 2017 | Review | Literature Analysis | Gene Electrotransfer (Plasmid DNA) | In this chapter we will present the International Network for Sharing Practices on Electrochemotherapy group, founded to answer the need of discussing issues and share experience on the use … |
| Irreversible | Leveque et al · Handbook of Electroporation | 2017 | Review | Literature Analysis | – | This chapter summarizes the experimental dosimetry techniques developed for exposures to high-intensity, ultrashort pulses in the nanosecond domain. The dosimetry or characterization of the … |
| Irreversible | Mi et al · Handbook of Electroporation | 2017 | Review | Literature Analysis | Nanosecond Pulsed Electric Field (nsPEF) | In order to explore the biomedical application of nanosecond pulsed electric fields (nsPEFs), researchers have used numerous methods to develop nanosecond pulse generators. Transmission line-… |
| Reversible | IGEA S.p.A. · – | – | Technical / Device Study | – | – | TECHNICAL SHEET INDEX 1. DESCRIPTION AND INTENDED USE OF CLINIPORATOR VITAE .......................................................................... 2 2. ACCESSORIES ......................… |
| Reversible | Pirc et al · SlovMedJour | 2018 | Protocol | – | – | Final goal of the study is to estimate the cost-e ectiveness of electrochemotherapy for the tre- atment of basal-cell carcinoma and skin melanoma. Paper consists of two parts: the first part… |
Limitations
The counts on this page are bounded by the scope of the source PDF archive and are not a systematic review of the area's literature. Study type and mechanism labels are derived automatically; for critical decisions consult the full texts of the publications listed. The evidence level reflects the number of publications, not their methodological quality.